Material Safety Data Sheet: Dipyrido[3,2-a:2',3'-c]phenazine

Identification

Product Name: Dipyrido[3,2-a:2',3'-c]phenazine
Chemical Formula: C18H10N4
Synonyms: DPPZ, Phenazine derivative
CAS Number: 220533-97-1
Recommended Use: Laboratory chemical, molecular probe
Manufacturer Information: Supplier and address as available on purchase documentation
Emergency Phone Number: Listed by supplier on purchase documentation

Hazard Identification

GHS Classification: Acute oral toxicity (Category 4), Skin and eye irritant (Category 2), Sensitization (Category 1)
Hazard Statements: Harmful if swallowed; causes skin, eye irritation; may cause allergic reaction
Pictograms: Exclamation mark
Signal Word: Warning
Precautionary Statements: Avoid inhalation, contact with skin and eyes; wear appropriate PPE; wash hands thoroughly after handling; eat and drink away from sample
Potential Health Effects: May cause headache, dizziness, nausea, and gastrointestinal discomfort; skin rash or asthma-like symptoms possible upon exposure
Environmental Hazards: Toxic to aquatic organisms by potential leaching or improper disposal

Composition / Information on Ingredients

Chemical Name: Dipyrido[3,2-a:2',3'-c]phenazine
Concentration: 98-100%
CAS Number: 220533-97-1
Molecular Weight: 282.30 g/mol
Impurities or Stabilizing Additives: No known additives; minor unidentified impurities can be present up to 2%

First Aid Measures

Inhalation: Move person to fresh air; seek medical attention if symptoms persist; monitor for delayed symptoms such as chest tightness or coughing
Skin Contact: Remove contaminated clothing; wash affected area thoroughly with soap and water for at least fifteen minutes; use emollient for irritation; medical attention for persistent symptoms
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and it is easy to do; seek immediate medical advice for persistent pain, redness, or vision changes
Ingestion: Rinse mouth thoroughly; do not induce vomiting unless told by a healthcare provider; seek medical help if feeling unwell
Symptoms and Effects: Nausea, drowsiness, irritation, or allergic reactions such as sneezing and shortness of breath
Medical Attention and Special Treatment: No specific antidote, treat symptomatically

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, or carbon dioxide
Unsuitable Extinguishing Media: Direct water jet may spread contaminant
Specific Hazards Arising: Thermal decomposition can release toxic or irritating fumes containing nitrogen oxides and carbon monoxide
Protective Equipment: Firefighters use chemical-resistant suit with self-contained breathing apparatus
Special Procedures: Avoid run-off into drains or waterways; cool containers with water fog under fire conditions

Accidental Release Measures

Personal Precautions: Wear nitrile gloves, lab coat, eye protection, and dust mask or respirator
Environmental Precautions: Prevent entry into drains, sewers, and natural water courses; notify authorities if large quantities escape
Methods for Clean-Up: Sweep or scoop spilled solid into suitable closed containers; use damp cloth or absorbent material for final wipe; ventilate affected area thoroughly; dispose via approved chemical waste route
Decontamination Procedures: Wash area with soap and water after spill clean-up; dispose rinsate safely

Handling and Storage

Precautions for Safe Handling: Use only in well-ventilated laboratory with chemical fume hood; avoid exposure to skin, eyes, and clothing; wear appropriate PPE at all times; do not eat, drink, or smoke in area
Conditions for Safe Storage: Store container tightly sealed in cool, dry place away from direct sunlight, incompatible materials such as strong oxidizing agents or acids
Incompatibilities: Strong oxidizers, strong acids, reducing agents
Storage Class: Chemical reagent/non-specific hazardous, based on lab policy

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established exposure limits for this compound
Engineering Controls: Local exhaust ventilation, chemical fume hood recommended
Personal Protective Equipment: Safety goggles, impermeable gloves such as nitrile or neoprene, buttoned lab coat, closed footwear; NIOSH-approved dust respirator for bulk handling
Hygiene Measures: Wash hands, face thoroughly after handling; take off contaminated clothing and wash before reuse
Environmental Controls: Avoid release to environment; monitor air and effluent for accidental contamination

Physical and Chemical Properties

Appearance: Orange to red crystalline powder
Odor: None detectable
Melting Point: Approx. 350°C (decomposes)
Boiling Point: Not applicable, decomposes before boiling
Solubility: Poorly soluble in water; soluble in DMSO, ethanol, methanol, chloroform
Density: 1.43 g/cm³ (approximate)
pH (solution): No reliable data; expect neutral to slightly acidic in suspension
Vapor Pressure: Negligible at standard conditions
Flash Point: Not readily flammable based on structure
Partition Coefficient (log Kow): Data limited; expect moderate hydrophobicity
Other Properties: Non-volatile; stable at room temperature

Stability and Reactivity

Chemical Stability: Stable under standard laboratory conditions, powder or solution form
Hazardous Reactions: May react with strong oxidizing or reducing agents to produce hazardous byproducts
Conditions to Avoid: Excessive heat, direct UV light, moisture, incompatible substances
Decomposition Products: Combustion or thermal decomposition produces carbon monoxide, nitrogen oxides, and other potential irritants
Polymerization: No known hazardous polymerization

Toxicological Information

Likely Routes of Exposure: Skin, eyes, inhalation, ingestion
Acute Effects: Harmful if swallowed, irritating to eyes or skin
Chronic Effects: No comprehensive chronic toxicity data; repeated exposure may sensitize or trigger allergies
LD50 (Oral, Rat): No published data; handle as toxic in the absence of evidence
Carcinogenicity: Not evaluated by IARC, NTP, or OSHA
Mutagenicity: No data; handle with standard lab precautions
Reproductive Toxicity: Not tested
Other Effects: Possible respiratory irritation with dust exposure, risk of contact dermatitis

Ecological Information

Aquatic Toxicity: Toxic to aquatic life in concentrated form; avoid discharge into environment
Persistence and Degradability: Structurally resistant to biodegradation; may persist in environment if released
Bioaccumulation Potential: Unknown, but parent compound features suggest low to moderate bioaccumulation
Mobility in Soil: Limited mobility due to low water solubility
Other Adverse Effects: Can contribute to chemical pollution if mismanaged; report or mitigate any accidental releases

Disposal Considerations

Waste Treatment Methods: Dispose as hazardous laboratory waste in accordance with official regulations
Container Disposal: Cleared containers to be triple-rinsed and sent for hazardous waste treatment; do not reuse containers for food, drink, or personal use
Additional Precautions: Incinerate with controlled emissions or handle according to institutional hazardous chemical policy
Relevant Regulations: Local and national waste management codes apply

Transport Information

UN Number: Not assigned for this specific compound
Transport Hazard Class: Not classified as dangerous under most transport rules
Packing Group: Not assigned
Special Precautions: Ensure secondary containment, protection from moisture during shipping; label as laboratory chemical, handle by trained personnel
Shipping Methods: Standard ground or air, provided container integrity and hazard communication
Environmental Hazards for Transport: Avoid uncontrolled release; immediately report and contain accidental spills

Regulatory Information

Applicable Regulations: Subject to general laboratory safety laws (OSHA Laboratory Standard, Chemical Hygiene Plan)
SARA Title III: Not listed as a specific substance
TSCA Status: May be subject to reporting, see supplier information
DSL/NDSL (Canada): Check with Canadian authorities for import or usage
WHMIS Classification: Laboratory chemical – hazard class based on irritation and sensitization
Restriction on Use: Research only, not for drug, food, or cosmetic use
Additional Information: Follow institutional chemical safety guidelines and reporting practices