Product Name: Cyanocobalamin
Synonyms: Vitamin B12, CNCbl
CAS Number: 68-19-9
Molecular Formula: C63H88CoN14O14P
Molecular Weight: 1355.37 g/mol
Recommended Use: Pharmaceutical ingredient, nutritional supplement, food additive
Supplier Information: Manufacturer or distributor details including emergency contact number, address, email for safety queries
Emergency Contact: Local poison control or manufacturer's emergency line
Classification: Cyanocobalamin does not fall under hazardous chemical categories for health or physicochemical risk according to GHS
Signal Word: None required by GHS
Hazard Statements: May cause mild irritation if inhaled, ingested or upon eye or skin contact in some sensitive individuals
Precautionary Statements: Avoid dust formation; prevent inhalation and contact with eyes and skin
Hazard Symbol: No pictogram assigned
Health Hazards: Allergic reactions in rare cases, minor respiratory tract irritation possible with excessive dust
Environmental Hazards: No major environmental risk under normal conditions
Chemical Name: Cyanocobalamin
Purity: ≥98.5%
Other Ingredients: May include minor stabilizers or excipients, depending on manufacturer
Chemical Family: Water-soluble vitamin
Impurities or Stabilizing Additives: Typically not above reporting thresholds or considered hazardous
Eye Contact: Rinse thoroughly with plenty of clean water for at least 10-15 minutes, lift eyelids, remove contact lenses
Skin Contact: Wash with soap and water, remove contaminated clothing
Inhalation: Move to fresh air, seek medical attention if persistent symptoms
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice if unusually high quantities are ingested
Note to Physicians: Treat symptomatically, no known antidote required
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or foam
Unsuitable Media: None specifically identified
Special Hazards arising from Substance: May produce toxic fumes of carbon oxides and nitrogen oxides if combusted
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective clothing
Fire/Explosion Hazard: Powder may form explosive dust-air mixtures in rare cases
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, oxides of nitrogen, cobalt oxides, hydrogen cyanide under high temperatures
Personal Precautions: Use personal protective equipment to prevent inhalation and contact with eyes and skin
Protective Equipment: Gloves, safety goggles, dust mask or respirator (if excessive dust)
Environmental Precautions: Prevent from entering drains, waterways, soil
Methods for Cleanup: Sweep or vacuum spilled powder carefully to avoid dust generation, clean up with damp cloth, store for disposal in closed container
Reference to Other Sections: Refer to Exposure Controls and Disposal Considerations for further handling instructions
Handling: Avoid contact with skin, eyes, and clothing. Work in ventilated area. Minimize dust generation and accumulation. Wash hands after handling.
Hygienic Practices: Do not eat, drink, or smoke in work area. Remove contaminated clothing promptly.
Storage: Keep tightly closed in original container, store in cool, dry, well-ventilated area away from direct sunlight, heat, and incompatible substances (strong oxidizers). Protect from moisture.
Incompatibilities: Avoid storing with strong acids, bases, or oxidizing agents.
Occupational Exposure Limits: No regulatory occupational exposure limit established for cyanocobalamin.
Engineering Controls: Use local exhaust ventilation, or general ventilation if significant dust forms.
Respiratory Protection: Use a suitable dust mask (EN 149 FFP2 or NIOSH N95) if dust is generated.
Eye Protection: Safety glasses with side shields.
Hand Protection: Disposable nitrile or latex gloves.
Other Protective Equipment: Laboratory coat or workwear to prevent skin contact.
Environmental Exposure Controls: Prevent from being released into large quantities in drains or natural water systems.
Appearance: Crystalline red or dark purple powder
Odor: Odorless
Melting Point: Decomposes at 230 – 240°C
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Freely soluble in water; slightly soluble in ethanol; practically insoluble in chloroform, ether, acetone
pH: Typically 4.5 – 7.0 (1% solution)
Vapor Pressure: Not applicable
Relative Density: About 1.44 g/cm³
Flash Point: Not applicable
Partition Coefficient (log Kow): Not available
Decomposition Temperature: Above 230°C
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions
Thermal Decomposition: Decomposes on strong heating, releases toxic fumes
Conditions to Avoid: Excess heat, moisture, direct sunlight, incompatible chemicals
Incompatible Materials: Strong acids, bases, oxidizers, reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, cobalt oxides if burned
Polymerization: Does not undergo dangerous polymerization
Acute Toxicity: Low acute toxicity; oral LD50 (rat) reported > 20 g/kg
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Health Effects: May cause mild respiratory or skin irritation; ingestion of high doses may produce allergic reactions in rare cases
Skin: Unlikely to cause long-lasting irritation
Eye: Dust may cause mechanical irritation and redness
Inhalation: Overexposure to dust may lead to transient respiratory irritation
Ingestion: High doses may cause mild gastrointestinal discomfort
Chronic Effects: No data suggesting harmful chronic effects; safe with standard supplementation practices
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity/Reproductive Toxicity: No data indicating significant hazard
Medical Conditions Aggravated: Hypersensitivity to cobalamin or cobalt
Ecotoxicity: Data on aquatic or terrestrial toxicity remains limited; considered low hazard to environment in dilute solutions
Persistence and Degradability: Not rapidly biodegradable, but expected to degrade slowly
Bioaccumulative Potential: No significant bioaccumulation anticipated owing to high water-solubility
Mobility in Soil: Mobility expected due to solubility in water
Other Adverse Effects: Large spills may cause oxygen depletion if released to natural waters due to high organic content
Waste Treatment Methods: Dispose of contents in accordance with local, regional, national, and international regulations
Unused Material: Can be sent to a licensed chemical disposal company, avoid landfill and sewage
Packing Materials: Decontaminate or discard according to applicable regulations
Special Precautions: Non-hazardous waste, but minimize release to environment
UN Number: Not regulated
Transport Hazard Class: Not classified as dangerous for transport
Proper Shipping Name: Cyanocobalamin
Packing Group: None assigned
Marine Pollutant: No
Special Precautions: Transport in compliance with regulatory requirements, secure packaging to prevent spillage and dust formation
Safety, Health and Environmental Regulations: Cyanocobalamin not subject to special hazard labeling under EU, US, or Canadian GHS criteria
TSCA: Listed
EINECS/ELINCS: Listed
DSL/NDSL: Listed
REACH: Exempt as a vitamin/nutrient product
Other Inventory Listings: Included in most national inventories, check country-specific compliance
Workplace Regulation: No mandatory exposure controls, though standard hygiene measures apply
Labeling Requirements: Standard chemical labeling with product name and manufacturer is advised
