Product Name: Cefoperazone
Chemical Formula: C25H27N9O8S2
CAS Number: 62893-19-0
Synonyms: Cefoperazone sodium, CPZ
Manufacturer: [Manufacturer details as per sourcing label]
Recommended Use: Antibiotic for bacterial infections
Emergency Phone Contact: Refer to local country poison control or manufacturer’s emergency contact
Hazard Class: Harmful if inhaled, swallowed, or absorbed through skin
Symbol: GHS07 (Exclamation mark), GHS08 (Health hazard)
Risk Phrases: R22 - Harmful if swallowed, R36/37/38 - Irritating to eyes, respiratory system, and skin
Target Organs: Kidneys, liver, gastrointestinal tract
Effects of Overexposure: Allergy-like reactions, rash, shortness of breath, nausea, gastrointestinal upset
Ingredient Name: Cefoperazone Sodium
Concentration: 100% (pharmaceutical grade may differ with buffer agents up to 10%)
CAS Number: 62893-19-0
Impurities: Trace amounts of buffer salts, sodium ions, manufacturing byproducts (specific identity by manufacturer data)
Inhalation: Move person to fresh air, seek medical attention if breathing issues occur
Skin Contact: Remove contaminated clothing, wash with water and soap thoroughly
Eye Contact: Rinse eyes with large volumes of water for 15 minutes, acquire medical help if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, seek physician advice immediately
Suitable Extinguishing Agents: Dry chemical powder, carbon dioxide, foam
Hazards from Combustion: Emits toxic fumes including oxides of nitrogen, sulfur, and carbon
Protective Equipment: Firefighters use NIOSH-approved self-contained breathing apparatus and protective clothing
Additional Information: Avoid breathing fumes, keep upwind of fire, prevent fire runoff from entering waterways
Personal Precautions: Wear gloves, safety goggles, lab coat; avoid inhalation of dust
Environmental Precautions: Do not discharge into sewers, surface, or groundwater
Clean-Up Methods: Sweep up material carefully, place in sealable appropriate waste containers, clean area with detergent and water
Disposal: Dispose as per hazardous pharmaceutical waste protocols
Handling: Use in well-ventilated area, avoid contact with skin, eyes, and clothing, keep containers tightly closed between uses
Storage: Store at 2–8°C, keep dry, protect from light, keep away from incompatible materials including strong oxidizing agents
Special Instructions: Avoid repeated exposure, record storage temperatures regularly for audit compliance
Workplace Exposure Limits: No official threshold set, limit airborne levels to minimum
Engineering Controls: Use local ventilation, biological safety cabinets where necessary
Personal Protective Equipment: Nitrile gloves, lab coat, chemical splash goggles, dust mask or respirator with HEPA filter for powder forms
Hygienic Practices: Wash hands after handling, avoid eating, drinking, or smoking in work area, decontaminate tools and surfaces after use
Appearance: White to off-white crystalline powder
Odor: Odorless
Molecular Weight: 667.7 g/mol
Solubility: Freely soluble in water, insoluble in ether
pH (1% solution): 4.0–6.0
Melting Point: Data not clearly established, decomposes at high temperatures
Stability: Stable at recommended storage conditions, hydrolyzes when mixed in aqueous solution for extended periods
Chemical Stability: Stable under recommended storage, sensitive to light and moisture
Conditions to Avoid: Strong oxidizers, alkaline conditions, excess heat, direct sunlight
Hazardous Decomposition: Degradation products include nitrogen oxides, sulfur oxides, carbon monoxide
Reactivity: No dangerous polymerization, incompatible with strong reducing agents or acids
Acute Toxicity: Oral LD50 (rat): >2000 mg/kg
Potential Effects: Allergic responses such as rash, asthma-like symptoms, gastrointestinal distress
Chronic Exposure: Prolonged contact may contribute to liver, kidney stress in animal data
Carcinogenicity: Not listed by IARC, NTP, OSHA
Reproductive Toxicity: Limited animal data, use with caution during pregnancy
Aquatic Toxicity: May be toxic to aquatic organisms in high concentrations, disrupts microbial balance
Persistence: Does not readily degrade in soil or water, stable under normal environmental conditions
Bioaccumulative Potential: Low; little evidence for significant accumulation
Mobility in Soil: Water-soluble, leaches through substrate, may reach groundwater with improper disposal
Precautions: Do not flush to surface water or drains, minimize environmental discharge overall
Waste Disposal: Collect and hand over to hazardous material authorities for incineration or controlled landfill
Contaminated Packaging: Rinse with water, dispose according to local hazardous waste regulations
Precautions: Do not reuse empty containers, avoid dispersal into environment, record all waste movements for compliance
UN Number: Not classified as dangerous for transport
Proper Shipping Name: Cefoperazone
Transport Hazard Class: Not regulated
Packaging Group: Not assigned
Special Precautions: Protect from moisture, physical damage, maintain packaging integrity
OSHA Status: Not specifically regulated; treat as hazardous chemical
TSCA Inventory: Cefoperazone as an active pharmaceutical ingredient exempt
EINECS/ELINCS: Listed as per European chemical regulations
Other Regulations: Follow workplace safety guidance for pharmaceuticals; ensure compliance with local, regional, and national medical waste protocols
