Product Name: Bronopol
Chemical Name: 2-Bromo-2-nitropropane-1,3-diol
CAS Number: 52-51-7
Use: Preservative, antimicrobial agent in industrial water systems, oilfields, personal care products
Synonyms: Bronosol, BNPD, Myacide, Bronidox, Onyxide 20
Manufacturer: Chemical suppliers specializing in industrial biocides
Contact for Emergency: National Poison Center, local emergency services, supplier emergency hotline
GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation) Category 4, Skin Irritation Category 2, Eye Damage Category 1, Aquatic Acute Category 1
Signal Word: Danger
Hazard Statements: Harmful if swallowed or in contact with skin, causes serious eye damage, causes skin irritation, very toxic to aquatic life
Pictograms: Exclamation mark, corrosion, environment
Precautionary Statements: Avoid breathing dust or mist, wash hands thoroughly after handling, avoid release to environment, wear protective gloves/eye protection/face protection, do not eat/drink/smoke when using
Other Dangers: May cause allergic skin reaction, possible mutagenic effects with chronic exposure
Substance: Bronopol
Concentration: 99% (technical grade), variable in diluted products
Other Ingredients: Trace impurities (less than 1%) may include unreacted starting materials or byproducts
Molecular Formula: C3H6BrNO4
Molecular Weight: 199 g/mol
If Inhaled: Move to fresh air, provide oxygen by trained personnel if breathing is difficult, seek medical attention if symptoms develop
If on Skin: Remove contaminated clothing, wash skin with plenty of soap and water, consult a physician for persistent irritation
If in Eyes: Rinse cautiously with water for several minutes, remove contact lenses if present and easy, continue rinsing, get immediate medical advice
If Swallowed: Rinse mouth, do not induce vomiting, get medical help
Most Important Symptoms: Severe eye irritation, redness, pain, skin irritation, headache, nausea if ingested or inhaled
Advice to Physicians: Treat symptomatically, consider chemical burns to eyes or mucous membranes, support respiratory and cardiovascular functions if necessary
Suitable Extinguishing Media: Dry chemical, CO₂, foam, water spray
Unsuitable Media: High-pressure water jet (may spread product)
Hazards from Combustion: Toxic gases such as hydrogen bromide, nitrogen oxides, carbon monoxide, carbon dioxide
Firefighter Protection: Self-contained breathing apparatus, chemical impermeable gloves, protective clothing
Special Tactics: Move containers from fire area if safe, use water spray to cool containers
Personal Precautions: Avoid direct contact, ventilate area, wear protective gloves, goggles, respiratory protection
Environmental Precautions: Prevent run-off into drains, waterways, soil
Methods for Cleanup: Contain spill with inert absorbent (sand, earth), collect into labeled containers for disposal, clean area with water, ventilate
Disposal: Manage as hazardous waste, follow local regulations
Handling: Use only with adequate ventilation, avoid dust generation, keep container tightly closed, do not eat, drink, or smoke near product
Storage: Store in cool, dry, well-ventilated space, original container preferred, keep away from incompatible substances such as strong acids, bases, and oxidizers
Special Notes: Avoid prolonged exposure to air and sunlight, store away from food and beverages, maintain temperature below 30°C
Occupational Exposure Limits: No established specific exposure limits; minimize workplace concentrations as low as practicable
Engineering Controls: Local exhaust ventilation, use in closed systems, emergency eyewash stations and showers
Personal Protection: Chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, laboratory coat or coveralls, NIOSH-approved respirator if dust is generated
Hygiene Measures: Wash hands and face before eating or drinking, remove contaminated clothing, wash before reuse
Appearance: White or off-white crystalline powder
Odor: Slight characteristic odor
Melting Point: 123–130°C
Boiling Point: Decomposes before boiling
Solubility: Readily soluble in water (25 g/100 mL at 25°C)
Vapor Pressure: Negligible at room temperature
Density: About 1.5 g/cm³
pH (aqueous solution): 5.0–7.0 (1% solution)
Partition Coefficient (log Kow): -0.6
Flammability: Not classified as flammable
Explosive Properties: Not explosive
Auto-Ignition Temperature: Not self-igniting
Chemical Stability: Stable under recommended storage and use conditions
Conditions to Avoid: Excessive heat, sunlight, moisture
Incompatible Materials: Strong acids, bases, oxidizers, reducing agents, strong alkalis
Hazardous Decomposition: Bromine, nitric oxide, hydrogen bromide, nitrous gases, carbon monoxide
Hazardous Reactions: No hazardous polymerization expected
Acute Toxicity: Oral LD50 (rat): 305 mg/kg, Dermal LD50 (rabbit): 1600 mg/kg
Inhalation: May cause respiratory tract irritation, based on dust or mist exposure
Skin Contact: Moderately irritating, may cause allergic reaction on prolonged or repeated contact
Eye Contact: Causes severe eye irritation or damage
Chronic Effects: Possible mutagenicity based on in vitro tests, repeated exposure may damage skin and mucous membranes
Sensitization: May trigger allergic response based on repeated skin contact
Carcinogenicity: Not classified as a carcinogen by ACGIH, IARC, NTP
Ecotoxicity: Very toxic to aquatic organisms (LC50 1.6 mg/L Daphnia magna 48hr, EC50 0.4 mg/L algae 72hr, LC50 0.1 mg/L fish 96hr)
Persistence and Degradability: Biodegradable in water, but slows down under anaerobic conditions
Bioaccumulation Potential: Low bioaccumulation (log Kow -0.6)
Mobility in Soil: High solubility means potential for leaching to groundwater
Other Harmful Effects: Active ingredient can disrupt microbial balance if released in significant amounts
Product Disposal: Send unused product for incineration or managed landfill by licensed waste contractor
Packaging Disposal: Triple rinse containers, puncture to prevent re-use, follow local container disposal law
Prevent Release: Avoid discharge to drains, watercourses, soil—even small amounts affect aquatic life
Special Instructions: Coordinate with approved hazardous waste facility, keep full documentation for regulatory compliance
UN Number: 3241
Proper Shipping Name: 2-Bromo-2-nitropropane-1,3-diol
Transport Hazard Class: 6.1 (toxic substance)
Packing Group: III
Label Required: Toxic
Marine Pollutant: Yes
Special Precautions: Avoid rough handling, segregate from incompatible goods, handle shipments with gloves and sealed containers
Inventory Listings: TSCA (USA), EINECS (EU), DSL (Canada), AICS (Australia), ENCS (Japan)
SARA Title III: Listed as a hazardous substance
OSHA Classification: Hazardous chemical covered by standard 29 CFR 1910.1200
Labeling Requirements: GHS compliant, hazard pictograms, signal words, and precautionary statements
Environmental Regulations: Subject to reporting under Clean Water Act and related water pollution laws
Other Restrictions: Use subject to regional biocidal product regulations, product-specific maximum concentration rules in cosmetics and industrial products
