Material Safety Data Sheet for Azacyclonol

Identification

Product Name: Azacyclonol
CAS Number: 115-46-8
Synonyms: 1-Azabicyclo[2.2.2]octan-3-ol, 3-beta-Hydroxy-1-azabicyclo[2.2.2]octane
Recommended Use: Pharmaceutical intermediate, research
Supplier: Pharmaceutical manufacturers and research chemical suppliers
Emergency Contact: Local Poison Control Center, local emergency services

Hazard Identification

GHS Classification: Not classified as hazardous under GHS
Route of Exposure: Inhalation, ingestion, skin contact, eye contact
Potential Health Effects: May cause skin and eye irritation, possible respiratory irritation
Signal Word: None
Pictogram(s): None due to low acute hazard, but standard laboratory precautions advised
Precautionary Statements: Avoid breathing dust, avoid direct contact with skin and eyes, use with adequate ventilation, wash hands after use
Symptoms of Overexposure: Possible headache, nausea, dizziness, mild irritation of respiratory tract, reddening or discomfort of eyes or skin

Composition / Information on Ingredients

Chemical Name: Azacyclonol
Purity: Typically >98%
Formula: C7H13NO
Molecular Weight: 127.18 g/mol
Impurities: Trace synthetic byproducts may be present depending on source, but should be minimal given typical pharmaceutical quality

First Aid Measures

Inhalation: Move exposed person to fresh air, keep at rest, consult physician if symptoms develop
Skin Contact: Immediately flush with plenty of water, remove contaminated clothing, seek medical attention if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, keep eyelids open, remove contact lenses if present and easy to do, continue rinsing, seek consultation if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention
Most Important Symptoms: Respiratory, skin, or eye irritation, possible mild central nervous system effects due to pharmacologic class

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, carbon dioxide, alcohol-resistant foam, or dry chemical powder
Specific Hazards: May emit toxic fumes of nitrogen oxides, carbon oxides under fire conditions
Special Protective Equipment: Wear self-contained breathing apparatus and full protective suit
Advice for Firefighters: Prevent runoff from entering drains or water sources, use appropriate tools to contain fire in chemical storage settings

Accidental Release Measures

Personal Precautions: Avoid dust formation, avoid inhalation, provide adequate ventilation, wear suitable protective gear
Environmental Precautions: Prevent release into sewer or waterways
Cleanup Method: Sweep up and place in suitable closed containers for disposal, clean spill area thoroughly with water and detergent, ventilate area
Disposal: Dispose of cleanup materials according to local, state, and federal regulations

Handling and Storage

Handling: Avoid breathing dust, use only in chemical fume hood or well-ventilated area, avoid contact with skin and eyes, handle with gloves and eye protection
Hygiene Practice: Wash thoroughly after handling, keep away from food and drink, avoid contamination of clothing
Storage Conditions: Store at room temperature in tightly closed container, protect from light and moisture, store separately from incompatible substances, keep away from oxidizers and acids
Incompatibilities: Strong acids, strong bases, oxidizing agents

Exposure Controls and Personal Protection

Exposure Limits: No specific occupational exposure limits established; use general chemical safety standards
Engineering Controls: Work in a fume hood or area with effective local exhaust
Personal Protective Equipment: Approved eye protection (goggles), chemically resistant gloves (nitrile or equivalent), lab coat, avoid skin contact, use NIOSH/MSHA-approved respirator if exposure to dust may occur
Environmental Controls: Follow all local environmental regulations for emissions and discharges

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless or faint chemical smell
Odor Threshold: Not reported
pH: Not applicable
Melting Point: 195-198°C
Boiling Point: Decomposes before boiling
Flash Point: Not applicable due to decomposition prior to boiling
Evaporation Rate: Not applicable
Flammability: Product does not ignite easily
Upper/Lower Flammability: Not determined
Vapor Pressure: Not available
Vapor Density: Not available
Relative Density: Not available
Solubility: Soluble in water and alcohol
Partition Coefficient: Not determined
Auto-Ignition Temperature: Not available
Decomposition Temperature: Begins near 200°C
Viscosity: Not applicable (solid)

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage
Reactivity: Inert under usual laboratory conditions
Conditions to Avoid: Strong heating, contact with incompatible materials
Materials to Avoid: Strong oxidizers, strong acids, strong bases
Hazardous Decomposition: Nitrogen oxides, carbon monoxide, carbon dioxide
Hazardous Polymerization: Will not occur

Toxicological Information

Acute Toxicity: No acute LD50 data reported for humans, low acute toxicity estimated from animal studies
Skin Corrosion/Irritation: May cause mild irritation on prolonged contact
Eye Damage/Irritation: Possible mild irritation
Respiratory/Skin Sensitization: Not expected to cause sensitization
Germ Cell Mutagenicity: No data
Carcinogenicity: Not listed by IARC, NTP, OSHA
Reproductive Toxicity: No data
Target Organ Toxicity: No specific target organ effects noted; CNS effects possible at high doses due to pharmacologic activity
Experience with Exposure: Irritation to eyes, skin, mucous membranes, possible drowsiness or mild excitement with significant exposure

Ecological Information

Ecotoxicity: No specific data, expected to have low toxicity to aquatic organisms given its structure and low usage quantity
Persistence and Degradability: Likely to degrade in environment based on structure (amines and alcohols generally break down in wastewater treatment)
Bioaccumulation Potential: Low, based on chemical structure and solubility
Mobility in Soil: Expected to be of moderate mobility due to solubility
Other Adverse Effects: Avoid uncontrolled release to environment to prevent unintended exposure

Disposal Considerations

Disposal Methods: Dispose of in accordance with all local, regional, national, and international regulations for chemical waste
Contaminated Packaging: Empty containers should be rinsed and disposed of as chemical waste
Special Precautions: Do not allow material to reach ground water, water course, or sewer without proper treatment
Incineration: Suitable for disposal by approved incineration facility with flue gas scrubbing

Transport Information

UN Number: Not assigned
Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Prevent package breakage, keep container tightly closed and upright, avoid mixing with incompatible materials during shipment

Regulatory Information

TSCA Status: Listed
EINECS/ELINCS: Listed
REACH Status: Not specifically registered
OSHA: Not regulated as hazardous
SARA Title III: Not listed as an extremely hazardous substance
California Proposition 65: Not listed
Other Regulations: This material should be handled with standard good laboratory practices and all local safety regulation compliance