Material Safety Data Sheet for 2-Aminothiazole-4-Acetic Acid

Identification

Product Name: 2-Aminothiazole-4-Acetic Acid
Chemical Formula: C5H6N2O2S
Other Names: Acetic Acid, 2-amino-1,3-thiazol-4-yl-, 2-Aminothiazole-4-Acetic Acid
CAS Number: 7374-34-9
Recommended Use: Research, Chemical Synthesis
Supplier: Laboratory or chemical supply company contact details
Emergency Contact: Local poison control center, company emergency line

Hazard Identification

Physical State: Solid, powder or crystalline
Classification: Harmful if swallowed, Skin and eye irritant
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, causes skin irritation, may cause respiratory irritation
Hazard Pictograms: Exclamation mark (GHS07)
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, use only outdoors or in a well-ventilated area, wear protective gloves and eye protection

Composition / Information on Ingredients

Chemical: 2-Aminothiazole-4-Acetic Acid
Concentration: ≥98% pure substance
Other Components: Trace synthetic or storage impurities possible, no significant stabilizers or additives reported
CAS Number: 7374-34-9

First Aid Measures

Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy, continue rinsing, seek medical attention if irritation persists
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, get medical help if skin irritation continues
Inhalation: Move to fresh air, keep comfortable for breathing, seek medical advice if symptoms like coughing or shortness of breath show up
Ingestion: Rinse mouth, do not induce vomiting unless trained to do so, seek immediate medical attention if feeling unwell or if large amounts have been ingested

Fire-Fighting Measures

Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Hazardous Combustion Products: Emits toxic fumes including nitrogen oxides, sulfur oxides, carbon monoxide, and carbon dioxide
Advice for Firefighters: Wear self-contained breathing apparatus, full protective gear, avoid inhaling combustion gases
Special Hazards: Fine particulates can form explosive dust-air mixtures, approach fire from upwind to avoid hazardous vapors

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, ventilate area, keep away from dust
Environmental Precautions: Prevent entry into drains, surface water, or soil to avoid contamination
Cleanup Methods: Scoop up material with non-sparking tools, avoid raising dust, place in suitable labeled containers for disposal, ventilate and wash spill area

Handling and Storage

Handling: Handle in well-ventilated place, wear suitable personal protective equipment, avoid breathing dust and avoid skin/eye contact, keep containers tightly closed
Storage: Store in a cool, dry, and well-ventilated area away from incompatible substances like strong oxidizers and acids, protect from light and moisture, keep container properly labeled

Exposure Controls and Personal Protection

Exposure Limits: No OSHA or ACGIH exposure limits currently established for this compound
Engineering Controls: Use chemical fume hood, local exhaust ventilation
Personal Protective Equipment: Safety goggles, lab coat, impervious gloves, dust mask or respirator if dust becomes airborne
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing and wash before reuse, avoid eating, drinking, or smoking while handling chemicals

Physical and Chemical Properties

Form: Crystalline solid or powder
Color: Off-white to light beige
Odor: Slight, characteristic odor
Molecular Weight: 158.18 g/mol
Sublimation/Boiling Point: Data not well established; estimated decomposition above 200°C
Melting Point: 236–238°C
Solubility: Soluble in water (variable), soluble in common organic solvents such as methanol, ethanol, and DMSO
pH (1% solution): Slightly acidic
Vapor Pressure: Not applicable for solids at room temperature
Density: Approximately 1.6 g/cm³ (estimation)

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Non-reactive under ordinary use, avoid contact with strong oxidizing agents, strong acids
Hazardous Decomposition: Produces toxic gases (NOx, SOx, CO, CO2) on combustion or decomposition
Conditions to Avoid: Excessive heat, exposure to humid air, direct sunlight, formation of dust

Toxicological Information

Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Effects: Irritation to eyes, skin, mucous membranes; ingestion may cause gastrointestinal upset
Chronic Effects: No chronic toxicity data established for humans
Toxicity Data: No specific LD50 values available, structurally similar compounds suggest low acute toxicity with primary hazard from irritation
Sensitization: No data on sensitization effects
Carcinogenicity: No components listed as known carcinogens

Ecological Information

Aquatic Toxicity: No specific data; minimize release to environment
Persistence and Degradability: Compound expected to slowly degrade in environment, not readily biodegradable
Bioaccumulation Potential: Expected to have low potential for bioaccumulation
Mobility: Likely to have moderate mobility in soil when dissolved in water
Other Adverse Effects: Avoid entry into waterways and drains, downstream effects unknown

Disposal Considerations

Waste Treatment Methods: Dispose of material according to federal, state, and local environmental control regulations
Disposal of Containers: Triple rinse and destroy empty containers, handle as hazardous waste
Precautions: Incinerate or use chemical landfill where permitted, avoid release into the environment, consult with certified waste disposal companies

Transport Information

UN Number: Not classified as dangerous goods according to current transportation regulations
Proper Shipping Name: Chemical for research use not otherwise specified
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Environmental Hazards: Not listed as marine pollutant
Special Precautions: Containers tightly sealed, clear labeling, handle with care during transit

Regulatory Information

International Inventories: Not listed on major international chemical registries (TSCA, EINECS, etc.) as of latest available data
U.S. Regulations: SARA 313 not listed, CERCLA not listed
EU Regulations: Not subject to specific restriction under REACH for REACH-registered substances
Labeling Requirements: GHS-compliant labeling recommended
Other National Regulations: Observe all applicable local, regional, and national regulations for research chemicals