Chemical Name: Acetylpyrazine
Synonyms: 2-Acetylpyrazine, Methyl pyrazinyl ketone
CAS Number: 22047-25-2
Use: Flavoring agent, fragrance ingredient, chemical synthesis intermediate
Manufacturer Details: Add contact information for supplier or responsible party
Emergency Contact: Emergency phone number for chemical spills or health emergencies
Classification: Eye irritant, Skin irritant
Main Hazards: May cause moderate eye discomfort, mild skin irritation, possible respiratory discomfort on high vapor concentration
GHS Label Elements: Exclamation mark symbol for irritation risks
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, possible respiratory irritation
Precautionary Statements: Avoid breathing dust or vapor, wash skin after handling, use only outdoors or in a well-ventilated area, wear protective gloves and eye protection
Chemical Identity: Acetylpyrazine
Concentration: >99%
Other Ingredients: Not applicable, single-component substance
Impurities: Trace pyrazine derivatives may be present in minor amounts due to synthesis routes
Inhalation: Move affected person to fresh air. If symptoms like coughing or shortness of breath persist, seek medical advice.
Skin Contact: Wash area with plenty of soap and water, remove contaminated clothing. For persistent redness or irritation, consult healthcare professional.
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing. Seek medical attention if irritation continues.
Ingestion: Rinse mouth, do not induce vomiting unless advised by a physician. If large amount swallowed or symptoms develop, obtain medical assistance.
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, or foam
Specific Hazards: Burning releases toxic fumes including carbon monoxide, carbon dioxide, nitrogen oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Special Procedures: Cool fire-exposed containers with water spray to prevent overheating. Prevent runoff from entering drains or waterways.
Personal Precautions: Use personal protective equipment including gloves, goggles, and mask
Environmental Precautions: Prevent from entering waterways, drains, and soil
Clean-up Methods: For small spills, absorb with inert material and place in chemical waste container. For large spills, isolate area and ventilate. Gather using nonsparking tools and dispose according to local guidelines.
Handling: Use with adequate ventilation, avoid skin and eye contact, do not inhale dust or vapors
Storage Conditions: Store in tightly closed original container in a cool, dry, and well-ventilated area, away from sources of heat and ignition
Incompatible Materials: Strong oxidizers, acids, bases
Exposure Limits: No established limits for acetylpyrazine (consult local regulations)
Engineering Controls: Use fume hood or local exhaust
Personal Protection: Chemical-resistant gloves (nitrile or neoprene), safety goggles, lab coat, adequate respiratory protection in poorly ventilated areas
Hygiene Measures: Wash hands and face after handling, do not eat or drink during use
Appearance: White to pale yellow crystalline solid
Molecular Formula: C6H6N2O
Molecular Weight: 122.13 g/mol
Odor: Nutty, popcorn-like aroma
Melting Point: 78–81°C
Boiling Point: Approx. 253°C at 760 mmHg
Solubility: Slightly soluble in water, readily soluble in organic solvents
Vapor Pressure: Low at room temperature
Flash Point: About 122°C (closed cup)
Density: 1.17 g/cm³ at 25°C
Chemical Stability: Stable under normal temperatures and pressures
Conditions to Avoid: Excessive heat, open flame, strong oxidizing agents
Incompatible Materials: Strong oxidizers
Hazardous Decomposition: Emits toxic gases (CO, CO₂, NOₓ) upon decomposition
Polymerization: Not known to occur
Acute Toxicity: Low toxicity expected under normal use
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Short-term Effects: May cause mild to moderate irritation to eyes, skin, and respiratory tract
Long-term Effects: Prolonged exposure could cause dermatitis; no evidence so far of carcinogenicity or mutagenicity in available literature
Symptoms: Eye redness, skin dryness, coughing, sore throat
Aquatic Toxicity: Not expected to be highly toxic, but data limited
Persistence and Degradability: Degrades slowly in environment, not highly persistent
Bioaccumulation: Not likely to bioaccumulate
Mobility in Soil: Not highly mobile, binds moderately to soil
Other Effects: Avoid direct release into the environment, as high concentrations could damage microorganisms and aquatic life
Disposal Methods: Dispose of in accordance with local, regional, and national regulations for chemical waste
Contaminated Packaging: Empty containers should be rinsed and sent for recycling or disposal as hazardous waste
Do Not Release: Don’t discharge directly to sewers or waterways
UN Number: Not classified as dangerous for transport
Transport Hazard Class: Not regulated
Packing Group: Not allocated
Special Precautions: Avoid excessive heat during transport, prevent physical damage to containers, keep upright
National Regulations: Check with local chemical safety directives and workplace regulations
International Inventories: Listed in TSCA, EINECS/ELINCS
Hazard Symbols: May be labeled as irritant according to GHS system
Right-To-Know: Subject to chemical hazard communication and reporting as outlined by OSHA and appropriate agencies
