Material Safety Data Sheet for Acetyl Morpholine

Identification

Product Name: Acetyl Morpholine
Chemical Formula: C6H11NO2
Synonyms: 4-Morpholineethanone, N-Acetyl Morpholine
CAS Number: 1696-20-4
Recommended Use: Industrial applications involving organic synthesis and chemical research
Supplier Contact: Information available through chemical distributor or manufacturer
Emergency Phone: Refer to national poison control or site manager

Hazard Identification

GHS Classification: Eye Irritation (Category 2), Acute Toxicity, Skin Irritant (Category 3)
Signal Word: Warning
Hazard Statements: Causes moderate to severe eye irritation, may cause mild skin irritation, harmful if swallowed or inhaled
Pictograms: Exclamation mark
Precautionary Statements: Avoid eye and skin contact, use adequate ventilation, do not eat, drink, or smoke near product, wash thoroughly after handling
Potential Health Effects: Eye redness and pain, mild skin rash, headache, dizziness from inhalation, nausea on ingestion

Composition / Information on Ingredients

Chemical Name: Acetyl Morpholine
Common Names: N-Acetyl Morpholine
Concentration: 98–100%
Impurities: Water (<1%), minor organic residues (<1%)
CAS Number: 1696-20-4
Molecular Weight: 129.16 g/mol

First Aid Measures

Inhalation: Move to fresh air right away, keep at rest, seek medical advice if symptoms persist, provide oxygen if breathing becomes labored
Skin Contact: Wash with soap and plenty of water, remove contaminated clothing, watch for signs of irritation, consult a doctor if irritation continues
Eye Contact: Rinse immediately with plenty of water for 15 minutes, hold eyelids apart, remove contact lenses if worn, continue rinsing, consult an ophthalmologist
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, immediate medical advice recommended

Fire-Fighting Measures

Flammability: Not classified as highly flammable, may decompose under fire conditions to form toxic fumes
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Special Hazards: Fire may result in release of hazardous vapors, including nitrogen oxides, carbon monoxide, and carbon dioxide
Protective Equipment: Firefighters should wear full protective gear and self-contained breathing apparatus in enclosed spaces
Advice for Firefighters: Use water spray to cool containers, evacuate area, approach from upwind to avoid smoke exposure

Accidental Release Measures

Personal Precautions: Avoid breathing dust, ventilate area, wear protective gloves, goggles, and clothing
Environmental Precautions: Prevent entry into drains, sewers, and waterways, contain spills using inert materials
Cleanup Methods: Absorb with sand or earth, transfer waste into suitable container for disposal, wash area with water and detergent, ventilate affected area
Emergency Procedures: Evacuate all nonessential personnel, follow site-specific chemical spill protocol

Handling and Storage

Handling: Always use in a well-ventilated location, wear protective equipment, avoid generating dust, keep container tightly closed
Storage: Store at room temperature in a dry, well-ventilated environment, keep away from heat, sparks, open flames, and incompatible materials like strong oxidizers
Incompatible Materials: Strong acids and bases, oxidizing agents, reactive metals
Other Precautions: Use proper grounding and bonding if transferring material, label storage area and containers, prevent static electricity buildup

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits, follow general industry guidelines for organic chemicals
Engineering Controls: Use local exhaust or general ventilation systems, process enclosure if needed
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, laboratory coat, closed shoes
Respiratory Protection: Use approved mask or respirator if dust or vapor develops over threshold limits
Hygiene Measures: Wash hands thoroughly after handling, change contaminated clothes immediately, do not eat, drink, or smoke in work area

Physical and Chemical Properties

Appearance: Clear or slightly yellowish liquid
Odor: Mild, slightly amine-like
Boiling Point: 107–110°C
Melting Point: -30°C (approximate)
Flash Point: 86°C (closed cup)
Solubility: Miscible with water, soluble in most organic solvents
Vapor Pressure: Low at room temperature
Density: About 1.08 g/cm³
Viscosity: Similar to water
Auto-Ignition Temperature: 320°C
pH: 6–8 (10% aqueous solution)

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Nonreactive under normal handling
Possible Hazardous Reactions: May react with strong acids, bases, and oxidizing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon dioxide, carbon monoxide
Conditions to Avoid: Excessive heat, open flame, incompatible chemicals, direct sunlight

Toxicological Information

Acute Toxicity: Moderate toxicity on oral exposure in animal studies (LD50 rat: 500–800 mg/kg)
Skin Contact: Can produce mild irritation, redness, and discomfort
Eye Contact: Produces irritation, pain, tearing
Inhalation: May irritate respiratory tract, can cause headache, dizziness or nausea if large quantities are inhaled
Sensitization: No evidence of skin or respiratory sensitization reported
Chronic Effects: No long-term toxicity data known, avoid repeated or prolonged exposure

Ecological Information

Ecotoxicity: Not considered highly toxic to aquatic life but may cause short-term harm in concentrated spills
Persistence and Degradability: Expected to be biodegradable under normal conditions
Bioaccumulative Potential: Low, does not strongly accumulate in living organisms
Mobility in Soil: Likely mobile in water and soil due to solubility
Additional Information: Avoid release to the environment, observe applicable regulations for aquatic protection

Disposal Considerations

Disposal Methods: Dispose of in accordance with local regulations, use licensed chemical waste contractor, do not pour down the drain
Container Handling: Triple rinse before disposal or recycling, puncture or crush to prevent reuse
Hazardous Waste Code: Consult national hazardous waste listings, usually not regulated as toxic waste unless contaminated
Precautions: Do not mix with incompatible wastes, label all disposal containers clearly

Transport Information

UN Number: Not classified as hazardous for transport
Proper Shipping Name: Acetyl Morpholine
Transport Hazard Class: Not regulated
Packing Group: None assigned
Special Precautions: Use leak-proof packaging, keep away from food and animal feed
Environmental Hazards: Not marine pollutant
Transport Labels: None required for nonhazardous chemicals

Regulatory Information

OSHA Status: Not listed as hazardous
TSCA Inventory: Listed
REACH Registration: Not registered in Europe without further notification
SARA Title III: Not subject to reporting requirements
WHMIS Classification: Not controlled
Other National Requirements: Check state/provincial listings and workplace regulations
Labelling: Appropriate chemical name and hazard information always required on immediate containers