Product Name: 7-Chloro-3-Methyl-1-Benzothiophene
Chemical Family: Benzothiophene derivatives
Molecular Formula: C9H7ClS
Molecular Weight: 182.67 g/mol
Chemical Abstracts Number (CAS): 15715-52-0
Synonyms: 7-Chloro-3-methylbenzo[b]thiophene
Intended Use: Research and development, intermediate in organic synthesis
Supplier Information: [Relevant supplier contact details]
Emergency Contact: [Emergency phone number specific for chemical incidents]
GHS Classification: Acute toxicity (oral), Skin irritation, Eye irritation, Specific target organ toxicity
Pictogram: Exclamation mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation
Precautionary Statements: Avoid breathing dust or vapors, wear protective gloves and eye protection, wash hands thoroughly after handling, do not eat or drink when using the product
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Potential Health Effects: May cause headache or nausea if inhaled in large quantities, skin redness or rash, eye pain or watering, gastrointestinal discomfort if ingested
Special Hazards: Dust form may present explosion risk in confined spaces if exposed to strong ignition sources
Chemical Name: 7-Chloro-3-Methyl-1-Benzothiophene
Purity: ≥97%
Impurities: Trace amounts of related benzothiophene derivatives (<1%)
Additives: None
Nature of Substance: Pure substance, no significant stabilizers or solvents included in packaging
Inhalation: Move to fresh air, keep at rest, seek medical advice if symptoms appear
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, seek attention for persistent discomfort
Eye Contact: Rinse with plenty of water for several minutes, remove contact lenses if present and easy, continue rinsing, consult ophthalmologist if irritation develops
Ingestion: Rinse mouth with water, do not induce vomiting, contact poison control or physician immediately
Notes to Physician: Treat symptomatically, consider supportive therapies for acute effects; monitor for respiratory or nervous symptoms as necessary
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam
Unsuitable Extinguishing Media: High-pressure water streams
Special Hazards: Combustion releases toxic chlorine and sulfur oxides, benzothiophene fumes may cause respiratory distress
Protective Equipment: Self-contained breathing apparatus and full protective suit for firefighters
Firefighting Procedures: Keep unnecessary personnel away, contain run-off to prevent entry into water systems, ventilate area after fire event
Fire/Explosion Risk: Dust accumulation in air may ignite, ensure proper ventilation to prevent buildup
Personal Precautions: Wear respirator, gloves, goggles, and protective clothing to prevent contact
Environmental Precautions: Prevent entry into sewers, surface water, or soil; inform authorities in case of large spill
Containment: Isolate spill area, restrict access, consider using inert absorbent material for cleanup
Cleanup Methods: Carefully collect spilled material in closed container, avoid creating dust, ventilate area well, store for proper disposal
Decontamination: Wipe area using wet paper towels, dispose of materials in accordance with local regulations
Handling: Work in hood or well-ventilated rooms, minimize dust generation, avoid all skin and eye contact, wash hands after handling
Storage: Store in tightly closed containers, in cool dry place away from direct light and oxidizers
Segregation: Do not store near foodstuffs or strong acids/bases, keep out of reach of children and unauthorized personnel
Incompatibles: Strong oxidizing agents, strong bases, moisture may degrade product
Storage Life: Check product-specific shelf life, monitor for color or texture changes that might indicate decomposition
Exposure Limits: Not established specifically for this compound, general dust exposure limit: 10 mg/m³ TWA
Engineering Controls: Local exhaust, chemical fume hood, avoid open handling in unventilated space
Personal Protective Equipment: NIOSH-approved dust mask or respirator in dust-prone conditions, chemical safety goggles, long-sleeved lab coat, nitrile or neoprene gloves
Hygiene Measures: Remove contaminated clothing before leaving work area, routine hand washing after handling chemicals, avoid eating or drinking during use
Appearance: White to pale yellow crystal or powder
Odor: Faint aromatic
Melting Point: 80–82°C
Boiling Point: 320°C (decomposes)
Solubility: Poorly soluble in water, soluble in most organic solvents like ethanol, acetone, dichloromethane
Vapor Pressure: Negligible at room temperature
Density: 1.36 g/cm³
pH: Not applicable
Partition Coefficient (log P): 3.8 (approximate)
Flash Point: Above 150°C
Evaporation Rate: Not measured due to low volatility
Auto-Ignition Temperature: Not determined
Explosive Properties: Not classified as explosive, caution with dust in air
Oxidizing Properties: Not classified as oxidizing
Chemical Stability: Stable if stored and handled under recommended conditions, sensitive to strong light and moisture
Conditions to Avoid: High temperature, exposure to direct sunlight, high humidity environments
Incompatible Materials: Strong oxidizers (e.g., peroxides), strong bases, strong acids
Hazardous Decomposition Products: Chlorine gas, sulfur oxides, unknown complex organic fragments
Polymerization: Does not undergo hazardous polymerization
Reactivity: Low under typical conditions, vigorous reaction possible with incompatible materials
Acute Toxicity: Oral LD50: Not fully determined, by analogy to related compounds, estimated at >500 mg/kg (rat)
Skin Contact: May produce irritation after prolonged or repeated exposure
Eye Contact: May cause severe irritation, redness, watering
Inhalation: Dust may irritate nose and respiratory tract, symptoms include coughing or throat discomfort
Chronic Effects: No long-term studies available for this compound; related structures show low to moderate sub-chronic toxicity
Carcinogenic Status: Not listed by IARC, NTP or OSHA as carcinogenic
Reproductive or Developmental Effects: No information for this compound, avoid exposure during pregnancy out of precaution
Signs/Symptoms of Overexposure: Skin/eye redness and discomfort, headache, dizziness, nausea if significant inhalation or ingestion occurs
Acute Aquatic Toxicity: Harmful to aquatic organisms based on measured and estimated data for benzothiophene derivatives, LC50 (fish) ~10-100 mg/L
Persistence and Degradability: Not readily biodegradable; may persist in environment
Bioaccumulation Potential: Significant due to hydrophobic structure and log P value
Mobility in Soil: Low water solubility suggests compound binds to organic matter, not mobile in most soils
Environmental Impact: Toxic to aquatic life with long lasting effects, avoid product release to drains or waterways
Other Adverse Effects: No significant ozone depletion, global warming or photoaccumulation expected
Waste Disposal Methods: Collect and contain hazardous residues, transfer to licensed hazardous waste facility
Incineration: Incinerate only in chemical incinerator equipped with afterburner and scrubber to manage chlorine and sulfur products
Container Disposal: Rinse empty containers with suitable solvent, discard as hazardous waste
Sewage Disposal: Do not discharge to sewer systems, potentially harmful to water treatment processes
Handling Unused Material: Store until proper disposal arranged by qualified personnel
UN Number: Not classified under UN Dangerous Goods at small scale
Proper Shipping Name: Organic solid, n.o.s. (contains 7-Chloro-3-Methyl-1-Benzothiophene)
Transport Hazard Class: Not regulated as hazardous for ground, air or sea at laboratory quantities
Packing Group: No assigned packing group
Special Precautions: Package securely to avoid dust release, label as hazardous if local requirements demand
Transport in Bulk: Not applicable at research/lab scale
Environmental Hazards: Substance harmful to aquatic life; prevent release during transport
Inventory Status: Not listed in EU’s REACH, US TSCA, Canada DSL, Japan ENCS
Labeling Requirements: GHS hazard symbols and warnings required per OSHA, EU CLP and relevant national rules
Workplace Safety: Subject to general chemical safety regulations, employee right-to-know requirements
Reporting Requirements: Large scale users may need to comply with environmental and occupational reporting
Restrictions: Intended for use by trained professionals in controlled settings only
Other Information: Manage in compliance with local, state, and country-specific chemical handling and environmental laws
