MSDS for 6-Methoxybenzothiazol-2-Ylamine

1. Identification

Product Name: 6-Methoxybenzothiazol-2-Ylamine
Synonyms: 2-Amino-6-methoxybenzothiazole
Chemical Formula: C8H8N2OS
Recommended Use: Laboratory reagent, chemical intermediate
Manufacturer Contact: Chemical manufacturer or supplier, emergency phone number available on provided label
CAS Number: 40615-36-9

2. Hazard Identification

Classification: Harmful if swallowed, skin and eye irritant
GHS Signal Word: Warning
Hazard Statements: May cause irritation to eyes, respiratory system, and skin; repeated or prolonged exposure can result in liver and kidney damage
Pictograms: Exclamation point
Routes of Exposure: Inhalation, ingestion, skin or eye contact
Target Organs: Eyes, skin, respiratory tract, liver, kidneys
Precautionary Statements: Avoid breathing dust or vapors, wear protective gloves, rinse eyes in case of contact, seek medical attention if symptoms persist

3. Composition / Information on Ingredients

Chemical Name: 6-Methoxybenzothiazol-2-Ylamine
Concentration: >98% by weight
Impurities: May contain trace organic contaminants (<1%), no significant hazardous impurities identified
Ingredient Registration: TSCA listed, not classified as a carcinogen by IARC, NTP, or OSHA under current regulations

4. First Aid Measures

Inhalation: Remove person to fresh air, provide oxygen if breathing is difficult, call for medical support if symptoms develop
Skin Contact: Wash with plenty of soap and water for at least 15 minutes, remove contaminated clothing, contact physician for persistent irritation
Eye Contact: Flush eyes with water for several minutes while lifting eyelids, seek medical attention if signs of irritation appear
Ingestion: Rinse mouth with water, do not induce vomiting, obtain medical assistance immediately
Most Important Symptoms: Irritation, coughing, burning sensation, headache, nausea

5. Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, water spray
Specific Hazards: Combustion produces toxic gases such as oxides of nitrogen, sulfur, and carbon
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective gear
Firefighting Instructions: Move containers from fire area if safe to do so, avoid inhaling combustion products, cool containers with water spray to prevent rupture
Flash Point: Data not available; treat as combustible solid

6. Accidental Release Measures

Personal Precautions: Wear appropriate respiratory protection, chemical goggles, gloves, and protective clothing
Environmental Precautions: Prevent entry into drains or waterways, notify environmental authorities if significant spillage occurs
Cleanup Methods: Sweep up and collect spill, place in suitable closed containers for disposal, ventilate area
Decontamination: Wash spill site thoroughly after removal procedures

7. Handling and Storage

Safe Handling: Use in a well-ventilated area, avoid dust generation, prevent contact with eyes and skin, wear recommended PPE
Storage Conditions: Store in tightly sealed containers, keep in cool, dry place away from light and incompatible materials such as strong oxidizers
Incompatibility: Strong acids, bases, oxidizing agents
Hygiene Measures: Wash hands and face after handling, remove contaminated clothing before entering eating areas
Special Procedures: Maintain good housekeeping to prevent accumulation of dust and residues

8. Exposure Controls and Personal Protection

Engineering Controls: Use in fume hood or with adequate local exhaust ventilation
Exposure Limits: No occupational exposure limits established; handle as irritant
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), safety glasses or goggles, lab coat, respiratory mask if dust forms
Environmental Exposure Controls: Prevent product entry into soil, waterways, and drains

9. Physical and Chemical Properties

Appearance: Off-white to pale yellow crystalline powder
Odor: Odorless or faint characteristic
pH: Not applicable (solid substance)
Melting Point: Approximately 169–172°C
Boiling Point: Decomposes before boiling
Flash Point: Data not specified
Solubility: Slightly soluble in water, soluble in ethanol and organic solvents
Vapor Pressure: Not significant at ambient temperature
Relative Density: No data found, estimated 1.3–1.4 g/cm³
Partition Coefficient (log Kow): Not tested
Autoignition Temperature: No information available
Explosive Properties: Not classified as explosive
Oxidizing Properties: Not classified as oxidizer

10. Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Condition to Avoid: Exposure to moisture, high temperatures, open flames
Incompatible Materials: Strong oxidizing agents, acids, alkali
Hazardous Decomposition Products: Oxides of carbon, sulfur dioxide, nitrogen oxides upon thermal decomposition
Polymerization: Not known to occur

11. Toxicological Information

Acute Toxicity: Oral (rat) LD50 estimated >500 mg/kg
Skin Irritation: May cause redness, dryness, or fissures on prolonged contact
Eye Irritation: Redness, discomfort, conjunctivitis possible
Respiratory Effects: Coughing, sore throat, difficulty breathing on high exposure
Chronic Exposure: Kidney or liver effects with repeated contact
Carcinogenicity: Not listed as carcinogenic to humans by IARC, ACGIH, NTP, or OSHA
Mutagenicity: No data available
Sensitization: Possible skin or respiratory sensitizer in predisposed individuals

12. Ecological Information

Aquatic Toxicity: Limited data available; may be harmful to aquatic organisms
Persistence and Degradability: Expected to be moderately persistent, biodegradability not established
Bioaccumulative Potential: Not determined; low volatility and moderate water solubility suggest low mobility in soil
Mobility in Soil: Low soil mobility expected
Other Adverse Effects: Prevent product from entering environment due to uncertainty over long-term impact

13. Disposal Considerations

Disposal Methods: Dispose of in accordance with local, regional, and national regulations for hazardous organic waste; incineration preferred if permitted
Contaminated Packaging: Rinse thoroughly and dispose of as chemical waste
Precautions: Avoid release to environment, do not mix with non-hazardous waste streams
Special Instructions: Consult qualified waste disposal contractor or local environmental authority

14. Transport Information

UN Number: Not regulated for transportation under ADR/RID/IMDG/IATA
Transport Hazard Class: Not assigned under current rules
Packing Group: Not assigned
Environmental Hazards: Not classified as a marine pollutant
Special Precautions: Secure packaging to prevent leakage or accidental release during transit, mark as chemical material

15. Regulatory Information

TSCA Status: Listed or exempt
EINECS/ELINCS: Listed
REACH Registration: Not pre-registered; handled according to local requirements
SARA Title III Sections 302/313: Not subject to reporting
California Proposition 65: No warning required
Labelling Requirements: Must be properly labelled under GHS with hazard pictograms and warnings
International Inventories: Present or permitted for restricted use, check specific jurisdictional requirements