Product Name: 5-Thiazolylmethanol
CAS Number: 6333-77-1
Synonyms: Thiazole-5-methanol
Chemical Formula: C4H5NOS
Recommended Use: Research, laboratory chemical synthesis
Manufacturer Contact: Refer to chemical supplier
Emergency Contact: Local emergency number or regional poison control
Molecular Weight: 115.16 g/mol
GHS Classification: Harmful if swallowed, causes skin irritation, causes serious eye irritation
Signal Word: Warning
Hazard Pictograms: Exclamation Mark
Hazard Statements: H302 Harmful if swallowed, H315 Causes skin irritation, H319 Causes serious eye irritation
Precautionary Statements: P264 Wash hands thoroughly after handling, P270 Do not eat/drink/smoke when using, P280 Wear protective gloves/eye protection/face protection
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Target Organs: Eyes, skin, digestive tract
Chemical Name: 5-Thiazolylmethanol
Concentration: ≥99% (pure solid sample)
Impurities: May contain trace residual moisture or organic solvent depending on source
Inhalation: Move person to fresh air; call a physician if symptoms like coughing or respiratory irritation persist
Skin Contact: Remove contaminated clothing; wash skin with plenty of soap and water; seek medical attention for persistent irritation
Eye Contact: Rinse eyes with water for several minutes, lifting eyelids occasionally; remove contact lenses if possible; obtain medical advice if irritation persists
Ingestion: Rinse mouth with water; do not induce vomiting unless directed by medical personnel; seek medical attention
Symptoms: Redness, irritation, headache, nausea
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Media: Direct water jet on burning powder
Hazards from Combustion: Toxic gases include nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Special Procedures: Avoid inhalation of combustion products; keep container cool with water spray
Personal Precautions: Ventilate area; avoid dust formation; wear appropriate personal protective equipment
Environmental Precautions: Prevent entry to waterways, sewers, soil
Methods for Cleanup: Sweep or scoop spilled material into a dry, labeled container; do not return product to original container; clean spill area with water and detergent
Handling Contaminated Materials: Dispose in accordance with local regulations
Handling: Minimize dust generation; handle in a chemical fume hood; avoid contact with skin, eyes, clothing; wash hands after handling
Storage: Store in a tightly closed container; keep in a cool, dry, well-ventilated place away from oxidizers, acids, and incompatible substances
Incompatible Materials: Strong acids, oxidizing agents
Storage Temperature: Stable under recommended conditions, room temperature preferred
Occupational Exposure Limits: No established OSHA or ACGIH exposure limits
Engineering Controls: Work in a ventilated area, preferably in a chemical fume hood
Respiratory Protection: Use NIOSH/MSHA-approved respirators if airborne dust or vapor is generated
Skin Protection: Wear chemical-resistant gloves, lab coat
Eye Protection: Safety goggles with side shields
Hygiene Measures: Avoid eating, drinking, or smoking while handling; wash hands and remove contaminated clothing before leaving work area
Appearance: White to off-white crystalline powder
Odor: Mild, characteristic thiazole smell
Odor Threshold: Not established
pH (aqueous solution): Slightly acidic (estimate)
Melting Point: 88-92°C
Boiling Point: Decomposition expected before boiling
Flash Point: Not available
Flammability: Not highly flammable under normal handling
Explosive Limits: Not established
Vapor Pressure: Negligible at room temperature
Density: 1.3-1.4 g/cm³ (estimate)
Solubility: Moderately soluble in water; soluble in ethanol, DMSO
Partition Coefficient (log Kow): Not measured
Auto-ignition Temperature: Not available
Decomposition Temperature: Not specified
Viscosity: Solid at room temperature, not applicable
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Low under ambient conditions
Possibility of Hazardous Reactions: Reacts with strong oxidizers and acids
Conditions to Avoid: Excess heat, open flame, incompatible substances
Hazardous Decomposition Products: Sulfur oxides, nitrogen oxides, carbon monoxide, carbon dioxide
Acute Toxicity: Data limited; may cause moderate irritation and acute effects if swallowed (based on structural analogy)
Skin Corrosion/Irritation: May cause irritation on prolonged or repeated contact
Serious Eye Damage/Irritation: May cause redness, tearing, discomfort
Respiratory Sensitization: Not expected, but dust inhalation should be minimized
Skin Sensitization: Not classified as a sensitizer
Chronic Effects: No established data on long-term exposure
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Mutagenicity: No studies found in literature
Reproductive Toxicity: Data unavailable; prudent lab practice recommended
Aquatic Toxicity: No specific data; avoid uncontrolled release to environment
Persistence and Degradability: Not studied in detail; predicted to be slowly biodegradable by analogy
Bioaccumulative Potential: No data; low log Kow suggests minimal bioaccumulation
Mobility in Soil: Expected to have moderate mobility due to water solubility
Other Adverse Effects: Uncontrolled runoff should be prevented to protect water bodies
Disposal Methods: Dispose of unused or excess material and contaminated containers as hazardous chemical waste; follow local, regional, national standards
Packing for Disposal: Place residues in properly labeled, sealed containers suitable for landfill or incineration by an approved waste disposal contractor
Sewage Disposal: Avoid discharge to wastewater treatment systems
Contaminated Packaging: Empty containers must be triple-rinsed; manage as hazardous waste
UN Number: Not assigned
UN Proper Shipping Name: Not regulated under UN transport regulations
Hazard Class: Not classified as hazardous for transport
Packing Group: Not applicable
Transport Label: No special labeling required
Special Precautions for User: Ensure packaging avoids breakage and exposure; prevent dust release
Environmental Hazards: Not a marine pollutant under IMDG
TSCA Inventory: Listed or for R&D use only
EINECS/ELINCS: Listed
SARA Title III: Not subject to SARA 313 reporting
California Prop 65: Not listed as a known carcinogen or reproductive toxicant
OSHA HazCom: Subject to chemical hazard communication standards
Other Regulations: Handle as a laboratory chemical; consult local authorities for additional compliance
