Product Name: 5-Oxo-DL-Proline
Synonyms: DL-Pyroglutamic acid, 5-Oxoproline
CAS Number: 4042-36-8
Recommended Use: Laboratory chemicals, industrial research and manufacturing
Supplier Information: Contact details provided by the distributor on original packaging
Emergency Phone Number: Consult local poison control center, or manufacturer’s listed emergency line
Classification: Not classified as hazardous according to GHS standards for this product
Signal Word: None
Hazard Statements: Generally regarded as safe, may cause mild eye or skin irritation if incidentally exposed
Precautionary Statements: Avoid dust formation. Handle with appropriate skin and eye protection
Physical Hazards: Minimal risk; avoid inhalation of powder
Health Hazards: Eye irritation, slight respiratory tract irritation, mild skin irritation on prolonged contact
Environmental Hazards: Low hazard to aquatic environments at normal lab concentrations
Label Elements: None required based on available data
Chemical Name: 5-Oxo-DL-Proline
Chemical Formula: C5H7NO3
CAS Number: 4042-36-8
Concentration: 100% (pure substance)
Impurities/Additional Information: No significant impurities relevant for safety are typically present
Inhalation: Move individual to fresh air; seek medical advice if symptoms occur
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing, seek medical attention if irritation persists
Eye Contact: Flush eyes with plenty of water for at least 15 minutes; remove contact lenses if present and easy to do, continue rinsing
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice if feeling unwell
General Advice: If symptoms persist after exposure, consult a doctor or poison control center
Suitable Extinguishing Media: Water mist, carbon dioxide, dry chemical, foam
Unsuitable Extinguishing Media: Do not use high pressure water stream
Special Hazards: Product does not burn readily, may emit nitrogen oxides or carbon oxides under extreme heat
Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective clothing
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, possible nitrogen oxides
Personal Precautions: Use appropriate personal protective equipment including gloves and goggles
Spill Cleanup Methods: Sweep up and collect in suitable containers for disposal; avoid dust formation
Preventive Measures: Ventilate area, clear unnecessary personnel, avoid breathing dust
Environmental Precautions: Avoid runoff into drains and waterways
Notification Procedures: Follow local, state, and national regulations for reporting significant spills
Handling: Keep containers tightly closed, handle product in a well-ventilated area, avoid producing dust
Safe Work Practices: Minimize direct contact, use recommended protective gear, do not eat or drink while using the substance
Storage: Store in a cool, dry, well-ventilated space away from incompatible substances like strong oxidizers
Storage Conditions: Containers should remain closed when not in use, store away from food and beverages
Occupational Exposure Limits: No specific exposure limits established for this substance
Engineering Controls: Use in a chemical fume hood if available for bulk handling
Personal Protective Equipment: Wear safety glasses or goggles, chemical-resistant gloves, and laboratory coat
Respiratory Protection: Use dust masks or respirators approved for nuisance particulates if dust generation is likely
Hygiene Measures: Wash hands before breaks and after handling, avoid prolonged skin exposure
Physical State: Solid
Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: 174–178 °C
Boiling Point: Decomposes before boiling
Solubility: Freely soluble in water
pH Value (in solution): Slightly acidic
Vapor Pressure: Negligible at room temperature
Density: Approximately 1.5 g/cm³
Partition Coefficient (n-octanol/water): Data unavailable or not applicable
Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: Excessive heat, contact with strong oxidizing agents
Incompatible Materials: Strong oxidizers, strong bases
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides if subjected to combustion or decomposition
Hazardous Reactions: Does not undergo hazardous polymerization under normal use
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Low toxicity; no data indicating acute effects at typical laboratory concentrations
Chronic Effects: Not classified as carcinogenic, mutagenic, or teratogenic based on available data
Symptoms of Overexposure: Mild respiratory or skin irritation, slight eye irritation possible
Target Organs: None identified
Other Information: Extensive exposure data not available; handle using good industrial hygiene practice
Aquatic Toxicity: Not expected to be toxic to aquatic life at standard usage levels
Persistence and Degradability: Will degrade in environmental conditions through typical biological pathways
Bioaccumulation Potential: Low, due to limited solubility in fats and fast degradation
Mobility in Soil: Expected to be moderately mobile
Other Adverse Effects: No evidence of significant environmental impact from small, controlled releases
Waste Disposal Methods: Dispose of in accordance with local, regional, national, and international regulations
Contaminated Packaging: Rinse empty containers with water and recycle or dispose of as appropriate
Handling Waste: Do not dispose into the environment, water courses, or household waste
Additional Guidance: Contact relevant authorities for guidance on appropriate disposal practices in your location
UN Number: Not regulated for transport
Proper Shipping Name: Not classified as hazardous
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Transport Labels: None required
Environmental Hazards During Transport: None under normal conditions
International Inventories: Appears on the chemical inventories of most significant jurisdictions (e.g., TSCA, EINECS)
Regulatory Status: Not classified as a dangerous substance or mixture under international and local regulations
Workplace Regulations: Employers should ensure that safety procedures and training cover the potential for eye, skin, and respiratory irritation
Other Regulations: No specific additional national or international regulations identified; reference local occupational health and safety standards for general chemical handling
