Product Name: 5-Methylpyrazine-2-Carboxylic Acid
Synonyms: 5-Methyl-2-pyrazinecarboxylic acid
Chemical Family: Pyrazine derivatives
Recommended Use: Research, intermediate in synthesis
CAS Number: 3222-00-2
Supplier: Specific supplier information on request
Emergency Number: Refer to local safety authorities or toxicology center
GHS Classification: Not classified as hazardous under GHS
Main Hazards: May irritate eyes, respiratory tract, and skin on contact or inhalation
Signal Word: None required
Pictograms: None mandated
Hazard Statements: May cause irritation to eyes, skin, and respiratory system
Precautionary Statements: Avoid dust formation, use with ventilation, wash face and hands after handling
Acute Effects: Irritation, coughing, mild headache if inhaled
Chemical Name: 5-Methylpyrazine-2-Carboxylic Acid
PURITY: ≥98%
CAS No.: 3222-00-2
Molecular Formula: C6H6N2O2
Component: Single substance
Impurities: Less than 2% (mainly trace related pyrazine derivatives)
Skin Contact: Rinse with plenty of water, remove contaminated clothing
Eye Contact: Flush eyes immediately with water for several minutes, seek medical advice
Inhalation: Move to fresh air, watch for breathing difficulty, get medical attention if symptoms persist
Ingestion: Rinse mouth, do not induce vomiting, get medical help
Advice to Physicians: Treat symptomatically, monitor for irritation or allergic reaction
Suitable Extinguishing Media: Use dry chemical, CO2, foam, or water spray
Special Hazards: Possible release of nitrogen oxides, carbon oxides during combustion
Firefighting Procedures: Wear protective gear and self-contained breathing apparatus
Explosion Hazards: Dust may form explosive mixture with air
Further Info: Cool unopened containers with water spray
Personal Precautions: Avoid dust formation, ventilate area, wear protective clothing
Environmental Precautions: Prevent entry into drains and waterways
Containment Methods: Sweep up, place in suitable sealed container
Cleanup Methods: Use moist cloth or vacuum with HEPA filter
Handling: Use with adequate ventilation, minimize dust generation, avoid contact with skin and eyes
Storage Conditions: Keep container tightly closed in cool, dry place; avoid exposure to moisture and heat
Incompatible Materials: Strong oxidizers, strong acids or bases
Hygiene Measures: Wash hands before breaks and at end of workday, keep away from food and beverages
Exposure Limits: No specific occupational exposure limits established
Engineering Controls: Use fume hood or exhaust ventilation
Personal Protective Equipment: Safety glasses, lab coat, gloves (nitrile or similar)
Respiratory Protection: Dust mask or respirator if ventilation is insufficient
Other Measures: Regularly inspect and clean protective equipment
Appearance: White to off-white crystalline powder
Odor: Faint, pyrazine-like
pH: Acidic when dissolved in water
Melting Point: 210–215°C (decomposes)
Boiling Point: Not available (decomposes before boiling)
Solubility: Slightly soluble in water and polar organic solvents
Density: Approximately 1.45 g/cm3
Vapor Pressure: Negligible at room temperature
Partition Coefficient: log Kow not measured
Flash Point: Not flammable under standard conditions
Chemical Stability: Stable under recommended storage conditions
Reactivity: Unreactive with most laboratory chemicals
Hazardous Reactions: None expected
Decomposition Products: Nitrogen oxides, carbon dioxide, carbon monoxide on combustion
Conditions to Avoid: Excessive heat, humidity, incompatible chemicals
Acute Toxicity: Oral LD50 not established, presumed low toxicity based on structure and analogs
Skin Corrosion/Irritation: May cause mild irritation
Eye Damage/Irritation: Expected to cause mild, reversible irritation
Respiratory Sensitization: No evidence for sensitization based on chemical class
Ingestion Effects: Large amounts may cause gastrointestinal upset
Chronic Effects: Not classified as carcinogen, mutagen, or reproductive toxin
Data Gaps: Limited animal or epidemiological data available
Aquatic Toxicity: No measured data, low anticipated environmental persistence
Mobility in Soil: Potential for partial mobility based on water solubility
Bioaccumulation: Low potential based on molecular size and solubility
Degradation: Expected to undergo slow biodegradation
Ecotoxicity: Avoid release into environment, precautionary principle applies in absence of data
Waste Handling: Deal with as chemical waste, do not discharge to environment
Disposal Methods: Incinerate with appropriate controls, dispose through authorized chemical waste contractor
Container Disposal: Triple rinse, puncture and deliver to specialized disposal facility
UN Number: Not classified as hazardous for transport
Transport Hazard Class: None
Packing Group: None assigned
Proper Shipping Name: 5-Methylpyrazine-2-Carboxylic Acid
Environmental Hazards: Not a marine pollutant
Additional Notes: Protect from direct sunlight and moisture during shipping
OSHA Status: Not regulated as hazardous
TSCA Status: Listed or meets TSCA requirements
REACH Status: Under exemption for low volume use for research
SARA Title III: Not listed as a hazardous or reportable substance
Other Regulations: Observe local, state and international chemical safety and handling requirements
