Product Name: 5-Chlorothiophene-2-sulfonamide
Synonyms: 5-Chloro-2-thiophenesulfonamide
CAS Number: 6363-21-5
Molecular Formula: C4H4ClNO2S2
Molecular Weight: 197.66 g/mol
Recommended Use: Laboratory chemical, research, intermediate for pharmaceuticals
Manufacturer: Not specified
Contact Details: Safety officer, laboratory supervisor
Emergency Phone: Local poison control, emergency response team contacts
GHS Classification: Acute toxicity (oral, dermal, inhalation); Eye irritation; Skin irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes skin irritation; causes serious eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid contact with skin and eyes, do not breathe dust or vapors, wear protective gloves, wash hands after handling
Potential Health Effects: Irritation to eyes, skin, respiratory system; ingestion may lead to upset stomach or more severe symptoms
Environment: May cause temporary harm to aquatic life
Chemical Identity: 5-Chlorothiophene-2-sulfonamide
Concentration: > 98% (by weight)
Impurities: May contain trace impurities from manufacturing process
Additives: None reported
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, seek medical attention if irritation persists
Skin Contact: Wash with plenty of soap and water, take off contaminated clothing, see a doctor if skin irritation occurs
Inhalation: Move person to fresh air, keep at rest in a position comfortable for breathing, consult a medical professional if symptoms like coughing or shortness of breath appear
Ingestion: Rinse mouth, do not induce vomiting, call a poison center or doctor right away
Most Important Symptoms: Stinging of eyes, skin redness or rash, respiratory discomfort
Advice to doctor: Treat symptomatically
Suitable Extinguishing Media: Water spray, dry chemical powder, CO2, foam
Unsuitable Media: Avoid direct water jet
Specific Hazards: Burning produces irritating, toxic fumes (nitrogen oxides, sulfur oxides, hydrochloric acid)
Protective Equipment: Self-contained breathing apparatus, protective clothing
Special Procedures: Move containers from fire area if possible, prevent run-off from contaminating overhead water
Personal Precautions: Use personal protective equipment, avoid dust formation, ventilate area
Environmental Precautions: Prevent entry into waterways, drains, and soil
Containment: Sweep up or vacuum without creating dust, collect in suitable container for disposal
Cleaning Methods: Wash area with water after material pick-up, dispose material as hazardous waste
Handling Precautions: Handle in a well-ventilated area, minimize dust, avoid skin and eye contact, avoid inhalation
Safe Storage Conditions: Store in tightly closed container, keep in cool, dry, well-ventilated area, protect from light, moisture, and incompatible substances (strong oxidizers, acids)
Hygiene Practices: Wash hands after use, do not eat, drink or smoke during handling
Exposure Limits: No occupational exposure limits established (use caution, treat as potentially hazardous)
Engineering Controls: Use fume hood, proper exhaust ventilation
Personal Protection: Wear protective gloves (nitrile recommended), safety goggles, lab coat, avoid inhaling dust or vapors, use respiratory protection if ventilation inadequate
Environmental Controls: Prevent release into the environment
Appearance: Off-white to pale yellow powder
Odor: No significant odor
Odor Threshold: No data available
pH: Not applicable (solid compound)
Melting Point/Freezing Point: 183 – 187 ℃
Boiling Point: No data available (decomposes on heating)
Flash Point: Not flammable under standard conditions
Evaporation Rate: Not applicable
Flammability: Not highly flammable
Vapor Pressure: Negligible at room temperature
Vapor Density: No data available
Solubility: Slightly soluble in water, more soluble in organic solvents like DMSO
Partition Coefficient: No data available
Auto-ignition Temperature: Not determined
Decomposition Temperature: May decompose above 200 ℃
Viscosity: Not applicable
Chemical Stability: Stable under normal laboratory conditions
Reactivity: Non-reactive with most common materials
Conditions to Avoid: Heat, moisture, light
Incompatible Materials: Strong oxidizing agents, strong acids
Hazardous Decomposition: Sulfur oxides, nitrogen oxides, chlorine-containing gases
Polymerization: Not expected under normal handling
Likely Routes of Exposure: Inhalation, skin, eye, ingestion
Acute Toxicity: LD50 (oral, rat): not well documented—handle as if harmful
Skin Corrosion/Irritation: Causes irritation, prolonged contact may lead to dermatitis
Serious Eye Damage/Irritation: Causes moderate to severe eye irritation
Respiratory or Skin Sensitization: Not classified but avoid dust/vapors
Germ Cell Mutagenicity: No data available
Carcinogenicity: No evidence in available studies
Reproductive Toxicity: Data not sufficient
Specific Target Organ Toxicity: Not classified
Aspiration Hazard: Not likely
Symptoms: Irritation to mucous membranes, coughing, redness, skin rash, abdominal pain if swallowed
Ecotoxicity: No comprehensive data, but sulfonamide and organochlorine substances may pose moderate toxicity to aquatic organisms
Persistence and Degradability: Substance alone can resist rapid degradation in environment, breakdown may take significant time
Bioaccumulative Potential: Limited data, unlikely to build up significantly in food chain
Mobility in Soil: Relatively low, substance not highly soluble in water
Other Adverse Effects: Runoff may cause short-term water contamination, encourage local containment practices
Disposal Methods: Dispose of as hazardous chemical waste
Contaminated Packaging: Dispose as chemical waste, do not reuse containers
Special Precautions: Keep waste separate from other trash, follow local, regional, and national waste regulations
Advice for Waste Handlers: Wear appropriate PPE during disposal, seek licensed professional waste disposal service
UN Number: Not assigned
Proper Shipping Name: Chemical, not otherwise specified
Transport Hazard Class: Not regulated as dangerous for land, sea, or air transport
Packing Group: Not classified
Environmental Hazards: Not classified as marine pollutant
Special Precautions for User: Avoid dust creation, carry in well-sealed containers, label package with content and hazard warning
Safety, Health and Environmental Regulations: No current listing as hazardous or controlled under US TSCA, EU REACH, Canadian DSL/NDSL, or other global chemical inventories
Labeling Requirements: Product should carry warning labels for skin and eye irritation, with chemical identification
Other Regulations: Follow workplace health and safety standards for laboratory chemicals; see local and national guidelines for environmental management
Additional Information: Regular review of new chemical safety data strongly recommended
