Product Name: 5-Chlorothiophene-2-Carboxylic Acid
Synonyms: 5-Chloro-2-thiophenecarboxylic acid
Chemical Formula: C5H3ClO2S
Molecular Weight: 162.60 g/mol
CAS Number: 24065-33-6
Recommended Use: Organic intermediate, chemical synthesis
Supplier Information: Detailed records of company, address, and emergency contact phone
Emergency Contact: 24-hour chemical emergency response team, local poison control center, or fire department
Classification: Skin irritation (Category 2), Eye irritation (Category 2A), Acute toxicity, oral (Category 4)
Signal Word: Warning
Hazard Statements: Harmful if swallowed; causes skin irritation; causes serious eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust; wash hands thoroughly after handling; use in ventilated locations; wear protective gloves, eye protection
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Target Organs: Eyes, skin, mucous membranes
Chemical Name: 5-Chlorothiophene-2-Carboxylic Acid
CAS Number: 24065-33-6
Concentration: More than 98% by weight
Impurities: Less than 2%, may include minor organic byproducts from synthesis
Inhalation: Move person to fresh air immediately; keep at rest; seek medical advice if symptoms develop
Skin Contact: Remove contaminated clothing and shoes; wash skin thoroughly with soap and water for several minutes; seek medical attention for persistent irritation
Eye Contact: Flush eyes thoroughly with water for 15 minutes, lifting eyelids; obtain medical attention as soon as possible
Ingestion: Rinse mouth, do not induce vomiting; seek medical advice and present this MSDS
Note to Physician: Treat symptomatically, ensure airways are clear, monitor for delayed reactions, provide supportive care
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam; water spray for larger fires
Special Hazards: Combustion may release toxic fumes including carbon oxides, sulfur oxides, hydrogen chloride, and other chlorinated compounds
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Specific Methods: Control run-off water; avoid contamination of drains and watercourses with firefighting water; contain material to prevent environmental release
Personal Precautions: Use appropriate PPE including gloves, goggles, and lab coat; avoid dust generation and inhalation
Environmental Precautions: Prevent entry into sewers, soil, and waterways; notify relevant authorities if substantial spills occur
Containment Methods: Use inert absorbent material to collect spills; sweep up carefully and transfer to a labeled waste container; ventilate the area
Cleaning Procedures: Clean contaminated area thoroughly after removal; dispose of absorbed material in accordance with local regulations
Safe Handling: Use in well-ventilated areas; avoid creating dust; avoid contact with eyes, skin, and clothing; do not eat, drink, or smoke during handling
Hygiene Measures: Wash hands face, and exposed skin after handling; regular cleaning of work surfaces
Storage Requirements: Store tightly closed in a cool, dry, and well-ventilated area away from incompatible substances like strong oxidizing agents or acids
Shelf Life: Stable for at least 2 years under recommended storage conditions
Incompatible Materials: Strong oxidizers, strong acids, bases, reducing agents
Engineering Controls: Use local exhaust ventilation; laboratory fume hood for powder manipulation; eye wash stations and safety showers
Respiratory Protection: Dust respirator or cartridge respirator for organic vapors in absence of adequate ventilation
Eye Protection: Chemical splash goggles or face shield for laboratory synthesis and handling
Skin Protection: Wear suitable gloves (nitrile or neoprene), laboratory coat, long sleeves;
Hygiene Precautions: Remove and wash contaminated clothing before reuse; do not handle with bare hands
Occupational Exposure Limits: No established limits published by OSHA, NIOSH, or ACGIH
Appearance: Off-white to light yellow crystalline powder
Odor: Faint, characteristic aromatic odor
pH: Not applicable for solid material
Melting Point: 137 - 140°C
Boiling Point: Decomposes prior to boiling
Solubility: Sparingly soluble in water; readily soluble in alcohols, acetone, and other polar organic solvents
Partition Coefficient (log P): Estimated at 1.7
Vapor Pressure: Negligible at room temperature
Relative Density: 1.55 (calculated)
Flash Point: Not determined for solid
Auto-ignition Temperature: Not easily flammable, not tested
Upper/Lower Flammability: Not available
Explosive Properties: No known explosive properties
Decomposition Temperature: Above 140°C
Chemical Stability: Stable at room temperature under recommended storage conditions
Reactivity: Unreactive under normal handling procedures; sensitive to strong oxidizing agents and acids
Conditions to Avoid: Excessive heat, ignition sources, prolonged exposure to light
Incompatible Materials: Strong oxidizers, strong acids, reducing agents
Hazardous Decomposition Products: Emission of toxic and corrosive fumes such as sulfur oxides, carbon oxides, hydrogen chloride, chlorinated organic compounds
Hazardous Polymerization: Will not occur under recommended use
Likely Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: Calculated oral LD50 (rat): ~2,000 mg/kg (estimated from structural analogs)
Skin Corrosion/Irritation: Irritation may result from direct contact, redness or discomfort
Serious Eye Damage/Irritation: Risk of severe irritation or transient injury from direct contact
Respiratory Sensitization: Not tested, avoid inhalation of dust
Carcinogenicity: No data available; not listed by IARC, NTP, OSHA
Mutagenicity: No known mutagenic effects
Reproductive Toxicity: No information available
Long-term Exposure: Repeated or prolonged contact may cause dermatitis or sensitization in sensitive persons
Ecotoxicity: No specific studies, but based on structure, may be toxic to aquatic organisms at high concentrations
Persistence and Degradability: May not be readily biodegradable, likely to persist in the environment for moderate periods
Bioaccumulation Potential: Slight potential for bioaccumulation based on partition coefficient
Mobility in Soil: Low to moderate due to limited water solubility
Other Adverse Effects: Spilled material may contaminate soil or water and impact aquatic life; avoid release to environment
Waste Disposal Methods: Dispose of as hazardous waste at an approved facility; follow local, state, and national regulations
Contaminated Packaging: Treat contaminated packaging as hazardous material; clean thoroughly before recycling or disposal
Recommended Disposal: Incineration is preferred for organic chemicals; chemical landfill if incineration not possible
Do Not: Release into drains, sewers, or local watercourses
UN Number: Not classified for transport under most regulations
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not hazardous under ADR, IMDG, or IATA
Packing Group: Not assigned
Special Transport Precautions: Keep tightly sealed during transport; protect from moisture and mechanical shock
Environmental Hazards: Not considered marine pollutant
Transport in Bulk: Not applicable in standard packaging
OSHA: Not classified as hazardous under 29 CFR 1910.1200
TSCA Status: Listed in the United States Toxic Substances Control Act Inventory
SARA Title III: Not subject to reporting under SARA Title III
California Proposition 65: Not listed as a chemical known to cause cancer, birth defects, or reproductive harm
EU Regulations: Not classified according to Regulation (EC) No 1272/2008 (CLP); safety data available on request
Canadian DSL/NDSL: Present on Domestic Substances List
Other International Inventories: Listed or exempted in most global regulatory chemical inventories
Labelling Requirements: Appropriate safety and hazard pictograms required in the workplace
