Product Name: 5-Bromobenzothiophene
Chemical Formula: C8H5BrS
Synonyms: 5-Bromo-1-benzothiophene, Benzothiophene, 5-bromo-
CAS Number: 5122-97-6
Manufacturer: List current maker or distributor details (name, address, emergency contact line).
Recommended Uses: Research, chemical synthesis, intermediate in organic compound preparation.
Restrictions: Not for drug, cosmetic, or food use. Only for labs with approved handling systems.
GHS Classification: Skin/eye irritation possible, Specific target organ system toxicity (single exposure), not classed as an acute toxin.
Label Elements: GHS07, exclamation mark pictogram.
Hazard Statements: Causes skin and eye irritation, may cause respiratory tract irritation.
Precautionary Statements: Wear gloves, avoid inhaling dust, handle away from food and drinks.
Routes of Exposure: Inhalation, skin and eye contact, ingestion.
Symptoms: Redness, itching, coughing, slight shortness of breath.
Environmental Impact: Slight hazard for aquatic organisms if large amounts released.
Chemical Name: 5-Bromobenzothiophene
CAS Number: 5122-97-6
Concentration: 97-99%
Impurities: Less than 3% trace benzothiophene derivatives and minor unknowns, depending on batch synthesis.
Inhalation: Remove to fresh air, loosen tight clothing, monitor for persistent cough or breathing difficulty.
Skin Contact: Rinse thoroughly with running water and mild soap, remove contaminated clothing.
Eye Contact: Gently flush with copious amounts of water for at least 15 minutes, lift upper and lower lids.
Ingestion: Rinse mouth out, do not induce vomiting, drink water if conscious.
Medical Attention: Seek prompt professional attention for any persistent symptoms or large exposures.
Suitable Extinguishing Media: Dry chemical powder, water spray, alcohol-resistant foam, or carbon dioxide.
Special Protective Equipment: Full firefighting gear, self-contained breathing apparatus.
Specific Hazards: Combustion releases toxic gases, including hydrogen bromide, sulfur oxides, and carbon oxides.
Advice for Firefighters: Keep containers cool with water, avoid breathing fumes, evacuate area if needed.
Flammability: Not highly flammable but may sustain combustion given enough fire exposure.
Personal Precautions: Use gloves, goggles, and mask. Ventilate area well.
Environmental Precautions: Prevent run-off to waterways or soil.
Containment: Scoop up solid carefully, avoid dust, place in sealed container.
Cleanup Methods: Wet absorbent material for dust, wash trace residues with soapy water.
Disposal: According to local hazardous laboratory waste guidelines.
Safe Handling: Work in fume hood, keep containers sealed, avoid inhaling dust and vapors.
Storage Conditions: Store in cool, dry, well-ventilated place out of sunlight and ignition sources.
Incompatibilities: Strong oxidizers, strong acids, alkalis; incompatible materials should be stored separately.
Specific Precautions: Do not store near food, drink, or feed; ensure spill kit is available in work area.
Engineering Controls: Use laboratory fume hood, local exhaust ventilation if operations generate dust/fume.
Eye Protection: Safety goggles or face shield.
Skin Protection: Use chemical-resistant gloves, lab coat, and long sleeves.
Respiratory Protection: Dust mask or cartridge respirator for organics if dusting occurs.
Hygiene: Wash hands after use, do not eat or drink in work area, remove contaminated clothing promptly.
Appearance: Pale yellow powder or crystals
Molecular Weight: 213.10 g/mol
Odor: Weak, not distinctive
Melting Point: 76-79°C
Boiling Point: Not readily available, thermal decomposition likely before boiling
Solubility: Poorly soluble in water, soluble in organic solvents like dichloromethane and ethanol
Vapor Pressure: Low
Density: 1.6–1.7 g/cm³
pH (Aqueous Dispersion): Neutral
Evaporation Rate: Not relevant for solid form
Chemical Stability: Stable under normal temperatures and storage conditions.
Reactive With: Strong oxidizers, reducing agents, and acids.
Decomposition Products: Hydrogen bromide, sulfur oxides, carbon monoxide, and carbon dioxide.
Conditions to Avoid: High temperatures, sparks, open flame, strong ultraviolet exposure.
Polymerization: Does not polymerize under routine use.
Acute Toxicity: Low but not well studied in humans, possible mild irritation to mucous membranes.
Skin/Eye Irritation: May cause mild reddening, itching, or burning.
Chronic Effects: No long-term animal testing data,
Inhalation: Can irritate respiratory tract, coughing possible.
Carcinogenicity: Not listed as carcinogen by IARC, NTP, or OSHA.
Reproductive Toxicity: No specific data.
Sensitization: Not expected to cause allergic response under normal use.
Ecotoxicity: Moderately toxic to aquatic organisms in large quantities.
Persistence and Degradability: May persist in environment for extended period; slow degradation.
Bioaccumulation: Potential for bioaccumulation in aquatic species not fully studied.
Mobility: Low mobility in soil due to hydrophobic nature.
Avoid Release: Prevent spillage to waterways or sewer systems.
Disposal Methods: Incinerate in approved facility if permitted. Otherwise, treat with hazardous chemical procedures.
Contaminated Packaging: Rinse thoroughly, dispose with hazardous waste.
Waste Codes: Refer to local hazardous waste classification.
Precautions: Never flush to drain or environment, avoid landfill if possible.
UN Number: Not regulated by road, air, or sea in most jurisdictions.
Transport Hazard Class: Not classified as dangerous.
Packing Group: Not applicable.
Labeling: Standard “Laboratory Chemicals” or specific to packing company.
Special Precautions: Ship in sealed containers, protect from moisture, keep away from oxidizers.
OSHA: Not regulated under OSHA’s hazardous chemicals standard.
TSCA (US): Listed in inventory.
EINECS/ELINCS (EU): Listed.
DSL/NDSL (Canada): May not be listed.
REACH: Exempted as research chemical.
Other National Inventories: Varies—always check local regulations.
Label Requirements: “For laboratory use only,” hazard pictogram and handling warnings.
Workplace Limits: No occupational exposure limits established.
