Product Name: 5-Amino Imidazole-4-Carboxamide
Chemical Formula: C4H6N4O
Synonyms: AICA, 4-Carbamoyl-1H-imidazol-5-amine
CAS Number: 2207-13-4
Recommended Use: Chemical synthesis, laboratory reagent, pharmaceutical intermediate
Supplier: Industrial and laboratory chemical suppliers
Contact Information: Refer to supplier safety contact provided on packaging
Classification: Acute toxicity (oral, category 4), Eye irritation (category 2A), Skin irritation (category 2)
GHS Label Elements: Exclamation mark, Harmful if swallowed or in contact with skin, Causes serious eye irritation
Potential Health Effects: Eye, skin, and respiratory tract irritation, headache, nausea from ingestion, allergic reactions with skin contact
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Specific Target Organ Toxicity: No known chronic effects, data limited
Environmental Hazards: Harmful to aquatic life with long lasting effects due to persistence
Substance: 5-Amino Imidazole-4-Carboxamide
Chemical Identity: C4H6N4O, 2207-13-4
Purity: > 98% (commonly supplied laboratory grade)
Impurities: Residual solvents, trace inorganic salts and byproducts below 2% (w/w)
Hazardous Components: No significant hazardous stabilizers or additives used in standard supply
Inhalation: Remove person to fresh air, provide oxygen if breathing is difficult, seek medical attention for persistent symptoms
Skin Contact: Remove contaminated clothing, wash affected area with soap and running water, medical consultation recommended for irritation or allergic reaction
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, hold lids open, seek prompt medical evaluation if irritation persists
Ingestion: Rinse mouth thoroughly, do not induce vomiting unless directed by medical personnel, seek emergency care
Acute Symptoms: Irritation, redness, gastrointestinal discomfort, eye watering
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray (do not use direct jet of water)
Specific Hazards: Material not highly flammable but decomposes in fire to nitrogen oxides, carbon oxides, toxic fumes
Protective Equipment: Firefighters use full protective gear and self-contained breathing apparatus
Fire Fighting Procedures: Move containers from fire area if possible, cool exposed drums with water mist, contain runoff to prevent environmental contamination
Combustion Products: Carbon dioxide, carbon monoxide, nitrogen compounds, organic vapors
Personal Precautions: Avoid contact with skin and eyes, ventilate area, use suitable personal protective equipment (PPE)
Spill Cleanup: Sweep or shovel material into suitable waste container, minimize dust, use HEPA vacuum for fine residue, wash contaminated surfaces thoroughly
Environmental Precautions: Prevent material from entering sewage or natural watercourses, report significant spills to authorities
Disposal: Dispose of cleanup material in accordance with local hazardous waste regulations
Safe Handling: Use in well-ventilated area, avoid inhalation of dust or fume, minimize skin and eye exposure, keep container tightly closed
Storage: Store in cool, dry, well-ventilated area, away from heat and incompatible materials such as strong oxidizers or acids
Incompatibilities: Strong acids, strong bases, oxidizing agents
Other Precautions: Keep out of reach of children, avoid sources of static or ignition, maintain proper labeling
Exposure Limits: No OSHA or ACGIH limits established, minimize workplace dust exposure by engineering control
Engineering Controls: Local exhaust ventilation, safety showers, eye wash stations
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), safety glasses with side shields or goggles, lab coat or apron, NIOSH-approved dust mask or respirator where dust is generated
Hygiene Measures: Wash hands after handling and before breaks or food, remove and wash contaminated clothing
Appearance: White to off-white crystalline powder
Odor: Odorless or faint chemical
Molecular Weight: 114.12 g/mol
pH (1% solution, water): 5.5-7.5 (weakly acidic to neutral)
Melting Point: 206-215°C (sublimation possible)
Boiling Point: Not applicable (decomposes on heating)
Flash Point: Data not available, combustion possible at high temperature
Solubility: Soluble in water, slightly soluble in ethanol
Vapor Pressure: Negligible at ambient temperature
Density: ~1.6 g/cm3
Partition Coefficient (log Kow): Not established
Evaporation Rate: Negligible
Chemical Stability: Stable under recommended storage, degrades in strong acid/base
Conditions to Avoid: Excess heat, moisture, direct sunlight, incompatible materials
Incompatible Materials: Strong oxidants, reducing agents, acids, alkalis
Hazardous Decomposition: Emits toxic gases of nitrogen oxides, carbon oxides during decomposition or combustion
Polymerization: No hazardous polymerization risk under standard conditions
Likely Exposure Routes: Inhalation, skin and eye contact, ingestion
Acute Effects: Moderate oral and skin toxicity (rat LD50 ~300-2000 mg/kg), mucous membrane irritation, reddening or rash from contact
Chronic Effects: Not well-studied, based on chemical structure possible kidney or liver involvement after prolonged exposure
Carcinogenicity: No listed as carcinogen by IARC, NTP, OSHA
Mutagenicity & Reproductive Toxicity: Limited data, no known mutagenic effects
Symptoms of Exposure: Nausea, vomiting, irritation, dizziness
Medical Conditions Aggravated: Pre-existing skin, eye, or respiratory problems
Aquatic Toxicity: Toxic to fish and aquatic organisms at moderate levels due to chemical persistence
Bioaccumulation: Potentially low, may accumulate in the environment due to slow biodegradation
Persistence and Degradability: Degrades gradually under environmental conditions, especially with light exposure
Mobility: Slightly mobile in soil, soluble in water aids leaching risk
Other Environmental Data: No data on ozone depletion or global warming impact
Waste Disposal Methods: Transfer unused or waste material to approved hazardous waste facility, incineration preferred, avoid landfill disposal
Empty Container Precautions: Decontaminate with water and dispose as hazardous waste
Local Regulations: Dispose in compliance with federal, state, and local environmental and safety laws
Additional Information: Do not release to surface waters or sewers
UN Number: Not classified under major transport regulations as dangerous good, verify per shipment
Proper Shipping Name: Chemical, not otherwise specified
Transport Hazard Class: Not regulated, handle with usual care
Packing Group: Not assigned
Environmental Hazards: Not marine pollutant, keep packages intact during transit
Transport Precautions: Avoid physical impacts, seal containers tightly, prevent package damage or leaks
Safety, Health and Environmental Regulations: Not listed under major chemical control lists (TSCA, REACH, DSL, ENCS) for specific restrictions
Labeling Requirements: GHS hazard label recommended, “Harmful if swallowed, irritating to eyes and skin”
SARA Title III: Not subject to reporting under Sections 302, 304, or 313
California Prop 65: Not listed
Workplace Use: Subject to general occupational health and safety regulations
Other Regulatory Info: Consult institutional and national regulations for additional requirements and updates
