Product Name: 4-Morpholinopropanesulphonic Acid
Synonyms: MOPS, 3-(N-Morpholino)propanesulfonic acid
CAS Number: 1132-61-2
Recommended Use: Laboratory reagent, buffer
Manufacturer Information: Supplier contact name, address, and emergency phone number required on each specific document
Emergency Contact: Number provided by manufacturer or obtained through CHEMTREC or regional chemical information center
GHS Classification: Not classified as hazardous by GHS criteria
Signal Word: None
Hazard Statements: None required under GHS
Precautionary Statements: Avoid inhalation, use personal protective equipment, minimize dust formation
Potential Health Effects: May cause mild irritation to eyes, skin, or respiratory tract during handling of powder
Environmental Hazards: No evidence of acute aquatic toxicity; caution advised for significant spills due to possible long-term effects
Chemical Name: 3-(N-Morpholino)propanesulfonic acid
Common Name: MOPS
CAS Number: 1132-61-2
Concentration: ≥ 99% (for laboratory-grade)
Impurities: Trace residuals and unreacted starting materials <1% (manufacturer-specific)
Molecular Formula: C7H15NO4S
Molecular Weight: 209.27 g/mol
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, seek medical attention if irritation persists
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, seek medical advice if rash or discomfort develops
Inhalation: Move to fresh air, keep individual warm and at rest, seek medical advice if symptoms present
Ingestion: Rinse mouth, do not induce vomiting, give water to drink if alert, obtain medical attention if unwell
Most Important Symptoms: Irritation, reddening, coughing, no known life-threatening effects in routine laboratory handling
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical or carbon dioxide
Unsuitable Media: Do not use powerful water jets, may spread contamination
Specific Hazards: May emit toxic fumes of nitrogen oxides, sulfur oxides, carbon oxides under fire conditions
Special Protective Equipment: Wear self-contained breathing apparatus, full protective clothing
Advice for Firefighters: Cool exposed containers, evacuate area, prevent runoff to drains or watercourses
Personal Precautions: Wear appropriate PPE, avoid dust formation, ensure adequate ventilation
Environmental Precautions: Prevent material from entering sewers and waterways, alert authorities if significant spill contaminates environment
Methods for Containment and Cleaning Up: Sweep up, place in suitable labeled container for disposal, avoid dust generation, clean spill site with water and detergent
Cleanup Personnel Protection: Use gloves, protective goggles, and dust mask during cleanup
Reference to Other Sections: Disposal and exposure guidance found in relevant sections
Precautions for Safe Handling: Handle in a chemical fume hood with adequate ventilation, wear suitable PPE, avoid contact with skin, eyes, and clothing
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing
Conditions for Safe Storage: Store in tightly sealed container in cool, dry, well-ventilated area, protect from moisture and incompatible substances
Storage Temperature: Typically between 2°C and 8°C for maximum stability
Incompatible Materials: Strong oxidizing agents, acids, bases not recommended for storage proximity
Occupational Exposure Limits: No specific value established; respect dust limits for nuisance particulates
Engineering Controls: Use local exhaust ventilation, laboratory fume hood preferred
Eye Protection: Chemical safety goggles or face shield
Skin Protection: Laboratory coats, impervious gloves resistant to chemicals
Respiratory Protection: NIOSH/MSHA approved dust mask where dust generation is possible
General Safety Measures: No eating, drinking, or smoking in work areas, wash after handling
Appearance: White crystalline powder
Odor: Odorless
Odor Threshold: Not available
pH (solution): 2.5 – 4.5 (50 g/L in water at 25°C)
Melting Point: 276 – 280°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not applicable
Flammability: Not flammable
Vapor Pressure: Negligible at room temperature
Solubility: Soluble in water (100 mg/mL at 20°C), insoluble in organic solvents
Specific Gravity: Approximately 1.4
Partition Coefficient: Not available
Evaporation Rate: Not applicable
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Not reactive with common laboratory chemicals under normal conditions
Possibility of Hazardous Reactions: Strong oxidizers may cause oxidation
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon oxides released during decomposition at high temperatures
Conditions to Avoid: Moisture, excessive heat, contact with incompatible chemicals
Incompatible Materials: Strong oxidizing agents, strong acids or bases may cause unexpected reactions
Routes of Exposure: Inhalation, skin, and eye contact, ingestion
Acute Toxicity: Oral LD50 (rat) >5000 mg/kg (not acutely toxic based on available animal data)
Skin Corrosion/Irritation: Mild irritation possible upon mucous membrane exposure
Serious Eye Damage/Irritation: Slight, reversible irritation reported at high concentrations
Respiratory Sensitization: No reported cases
Skin Sensitization: Not classified as skin sensitizer
Germ Cell Mutagenicity: Not known to be mutagenic
Carcinogenicity: Not classified as a carcinogen
Reproductive Toxicity: No information suggesting reproductive harm
Additional Information: Chronic exposure may cause dryness or cracking of skin, increased potential for mild irritation
Ecotoxicity: Not considered acutely toxic to aquatic organisms based on typical concentrations and available data
Persistence and Degradability: Biodegradable over time under natural environmental conditions
Bioaccumulative Potential: Low potential due to high water solubility and low log Kow
Mobility in Soil: Expected to have high mobility
Other Adverse Effects: No evidence of harm to plants, animals, or microorganisms in standard laboratory discharges
Product Disposal: Dispose of in accordance with local, regional, and national regulations, typically through chemical waste specialist
Contaminated Packaging: Rinse thoroughly, dispose of as laboratory chemical waste
Waste Codes: Not hazardous waste per US EPA RCRA listings but check local regulations for categorical inclusion
Disposal Methods: Do not release to environment, do not pour down drain in significant quantities
UN Number: Not regulated as hazardous for transport
Proper Shipping Name: Not dangerous goods
Transport Hazard Class: None assigned
Packing Group: Not applicable
Marine Pollutant: Not classified as marine pollutant
Special Precautions: Keep containers tightly closed, avoid rough handling and package rupture
Safety, Health, and Environmental Regulations: Listed in TSCA (US), EINECS (Europe), and other major chemical inventories
SARA/OSHA Status: Not listed as hazardous; no section 313 chemicals present
California Prop 65: Not listed
WHMIS (Canada): Not classified as hazardous
REACH (Europe): Exempt for low-volume laboratory use, not subject to authorization
Other Regulatory Information: Observe local occupational health and chemical safety standards while using this compound
