Product Name: 4-Methylthiazole-5-Carboxylic Acid
CAS Number: 1193-82-2
Synonyms: 4-Methyl-1,3-thiazole-5-carboxylic acid
Recommended Use: Laboratory research, chemical synthesis
Supplier Details: Manufacturer address, business phone, emergency contact, technical service hotline
Email: Safety compliance or customer support email for additional guidance
Product Number: Batch or lot number tied to inventory and traceability
Contact for SDS Request: Dedicated compliance or regulatory department number
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Specific target organ toxicity - single exposure (Category 3), Acute oral toxicity (Category 4)
Signal Word: Warning
Hazard Statements: Causes moderate eye and skin irritation, may irritate respiratory tract, harmful if swallowed
Precautionary Statements: Avoid breathing dust or vapors, wash hands thoroughly after handling, wear protective gloves and safety goggles, use only outdoors or in well-ventilated areas
Pictograms: Exclamation mark symbol (GHS07)
Potential Health Effects: Shortness of breath, skin redness, eye discomfort, sore throat
NFPA Ratings: Health - 2, Flammability - 1, Instability - 0
Emergency Overview: White to off-white crystalline solid, may emit unpleasant sulfur odor, dust may irritate eyes or throat
Chemical Name: 4-Methylthiazole-5-Carboxylic Acid
CAS Number: 1193-82-2
Purity: Greater than 98% as found from supplier certificate of analysis
Impurities: Minor quantities of related thiazole derivatives or residual solvents, trace moisture
Other Ingredients: Not intentionally added, product does not contain fillers or additives
Molecular Formula: C5H5NO2S
Molecular Weight: 143.17 g/mol
EC Number: 214-770-5
Inhalation: Move to fresh air, provide oxygen or artificial respiration if breathing is difficult, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, monitor for persistent redness or rash
Eye Contact: Flush eyes gently with plenty of running water for at least 15 minutes, lift eyelids occasionally, seek immediate medical attention
Ingestion: Rinse mouth with water, avoid inducing vomiting unless instructed by a medical professional, call for medical help right away
Most Important Symptoms: Sneezing, burning sensation in throat or eyes, skin inflammation
Notes to Physician: Symptomatic treatment, monitor airway and respiratory function, no known specific antidote
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or foam
Unsuitable Extinguishing Media: Direct water jet, due to risk of dust dispersion
Specific Hazards: Will decompose under intense heat, possible emission of toxic fumes such as nitrogen oxides, sulfur oxides, carbon monoxide and dioxide
Protective Equipment: Full fire-fighting turn-out gear, self-contained breathing apparatus recommended
Special Procedures: Prevent run-off from entering drains, cool exposed closed containers with water spray, evacuate area if significant quantities are involved
Combustion Products: Fumes containing sulfur compounds, nitrogen oxides, organic fragments
Personal Precautions: Wear chemical-resistant gloves, goggles, and dust mask, avoid breathing dust, keep unnecessary people away
Environmental Precautions: Prevent entry into sewers and public waterways, use absorbents around spill zone
Methods for Cleanup: Carefully sweep up and collect spill, minimize dust generation, place material into properly labeled containers for disposal
Decontamination: Wash contaminated area with mild soap and water, ventilate area, inspect for residue
Emergency Procedures: Notify safety team or spill response crew, cordon off immediate area, dispose of cleanup materials as hazardous waste
Handling: Work in well-ventilated areas, avoid raising dust, keep container tightly sealed when not in use, do not eat or drink while handling the substance
Hygiene Practices: Wash hands before breaks and at end of work day, avoid inhalation or direct contact with skin and eyes, change out of potentially contaminated clothing
Storage Conditions: Store in a cool, dry place, keep away from incompatible materials such as strong bases or oxidizers, protect from direct sunlight and significant temperature swings
Container Requirements: Keep substance in original container, use chemical-resistant secondary containment
Storage Class: Chemical storage for acids or hazardous organics, routine inspections advised to check for leaking or weakened containers
Occupational Exposure Limits: No specific threshold limit values established, standard practices for laboratory chemical handling apply
Engineering Controls: Use chemical fume hood or local exhaust ventilation for dust reduction, keep air exchange adequate in work space
Personal Protection Equipment: Safety goggles, gloves (nitrile or butyl rubber), lab coat, dust mask or NIOSH-approved respirator in presence of airborne particles
Environmental Controls: Do not allow product to enter water sources or soil, engineered controls should limit environmental discharge
General Protective Measures: Avoid skin and eye contact, handle only with tools or scoops designed for chemical handling, keep open flames and ignition sources away from storage and working areas
Physical State: Crystalline solid
Color: White to slightly off-white
Odor: Mildly characteristic, sulfurous
Melting Point: Around 190-194°C
Boiling Point: Not available (decomposes before boiling)
Flash Point: Not determined, likely above ambient temperature due to low volatility
Solubility: Slightly soluble in water, more soluble in polar organic solvents (e.g., methanol, DMSO)
pH (solution): Slightly acidic in water
Vapor Pressure: Negligible at room temperature
Density: Approximately 1.5 g/cm3
Partition Coefficient (log Kow): Data not widely available, expected to be moderately low due to carboxylic acid group
Evaporation Rate: Not relevant for solid
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Inert at room temperature, transforms under acidic or basic catalysts
Conditions to Avoid: Strong oxidizing agents, alkaline substances, strong acids, prolonged exposure to moisture
Hazardous Decomposition: Under combustion or decomposition, produces nitrogen oxides, sulfur dioxide, carbon monoxide and carbon dioxide
Polymerization: No hazardous polymerization expected under normal conditions
Incompatibilities: Avoid mixing with alkali metals, reducing agents, strong bases, and oxidizing materials
Routes of Exposure: Inhalation, ingestion, dermal, ocular
Acute Toxicity: Ingestion may cause nausea, vomiting; dust inhalation can irritate respiratory tract, eye and skin irritation likely
Chronic Effects: Not fully evaluated, repeated exposure could trigger allergic response or dermatitis
Symptoms of Exposure: Burning or stinging eyes, pruritus, mild respiratory discomfort, minor gastrointestinal upset
Carcinogenicity: Not known to be classified as human carcinogen by IARC, NTP, or OSHA
Mutagenicity: No data available
Reproductive Effects: No studies identified, avoid chronic exposure due to lack of full toxicological profile
Target Organs: Eyes, skin, upper respiratory tract
Eco-Toxicity: Limited data, likely to have low acute aquatic toxicity due to low solubility
Persistence and Degradability: May not degrade rapidly in environment, small molecule with potential for slow breakdown under biological conditions
Bioaccumulation: Not expected due to water solubility and low Kow
Mobility: Solid may settle in soil, unlikely to migrate in water column
Other Hazardous Effects: Avoid unintentional environmental discharge, do not allow chemical to enter storm drains or water systems
Precautions: Use containment to prevent run-off into environment, gather residues and dispose as hazardous waste
Waste Handling: Collect in properly labeled container, treat as hazardous laboratory waste
Disposal Methods: Send to licensed chemical disposal contractor, do not discharge residues into public sewage
Packing for Disposal: Use sealed, compatible containers to prevent leaks during transport
Disposal Regulations: Comply with regional and national hazardous waste rules
Cleaning Materials: Incinerate contaminated materials if safe and permitted, otherwise landfill as hazardous material per local guidance
UN Number: Not regulated for transport by most authorities, verify status for unusual shipments
Proper Shipping Name: Laboratory Chemicals, N.O.S. (not otherwise specified)
Transport Hazard Class: Not classified as dangerous under standard shipping laws
Packing Group: III (low danger) if shipping in bulk
Marine Pollutant: Not listed
Special Precautions: Securely package to prevent container breakage or powder release
Documentation: Include SDS and shipping papers, label as “Not for food or drug use”
OSHA Status: Not listed as hazardous under US Occupational Safety and Health Act
TSCA: Listed on Toxic Substances Control Act Inventory
EU REACH: Compliance requirements depend on volume imported or manufactured, not included on candidate list of substances of very high concern
WHMIS (Canada): Not classified under current regulations
SARA Section 313: Not subject to reporting
California Proposition 65: Not listed
Other Regulations: Check local, regional, and national standards for chemical use, storage, waste disposal, and exposure controls
