Chemical Name: 4-Ethylmorpholine
CAS Number: 5636-21-5
Synonyms: N-Ethylmorpholine, Morpholine, 4-ethyl-
Recommended Use: Intermediate for dyes, pharmaceuticals, chemical research
Supplier: Company name, address, and emergency phone number to be filled per sourcing
Emergency Contact Number: Local country poison control or chemical emergency service number
Product Code: Lab reference or commercial catalog code
Manufacturer Information: Manufacturer address, helpline, and contact details as per safety guidelines
Classification: Flammable liquid, corrosive to skin and eyes, causes severe irritation to respiratory tract
GHS Label: Flame, Corrosive, Exclamation mark
Signal Word: Danger
Hazard Statements: Harmful if swallowed, causes burns, vapor irritating to nose, class 3 flammable liquid
Precautionary Statements: Wear gloves, eye, and face protection, keep away from heat or sparks, avoid inhalation of vapor or mist, wash exposed skin thoroughly
Potential Health Effects: Burns on contact, severe eye damage, respiratory irritation, long exposure risk for organ damage
Routes of Exposure: Inhalation, ingestion, skin absorption
Environmental Impact: Harmful to aquatic life, persistent in soil, not easily biodegradable
Ingredient: 4-Ethylmorpholine
CAS#: 5636-21-5
Concentration: ≥98%
Impurities: Trace morpholine derivatives, water, residual solvents under 1%
Additives: None declared, pure bulk chemicals typically have no additives
Form: Liquid clear to pale yellow, sharp odor
Inhalation: Move outside to fresh air, loosen tight clothing, monitor breathing, seek medical help if symptoms persist
Skin Contact: Immediately flush skin with water for 15 minutes, remove contaminated clothes and shoes, seek medical advice for burns
Eye Contact: Rinse eyes thoroughly with water for at least 15 minutes, lift eyelids occasionally, visit an eye doctor urgently
Ingestion: Rinse mouth, do not induce vomiting, offer water, consult a poison center, medical advice crucial
Delays: Symptoms of respiratory trouble or blistered skin can appear late, err on side of caution and seek help
Suitable Extinguishing Media: Dry chemicals, alcohol-resistant foam, carbon dioxide, do not use direct water jet
Special Hazards: Vapors spread easily, risk of explosion near sparks, thermal decomposition can release toxic fumes like nitrogen oxides
Firefighting Instructions: Approach from upwind, keep fire-exposed containers cool with water spray, wear full-body protective gear and breathing apparatus
Protective Equipment: Self-contained breathing apparatus, chemical-resistant suit and gloves
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides, possibly irritating or corrosive gases
Personal Precautions: Ventilate area, evacuate unprotected personnel, use chemical goggles and gloves, avoid breathing vapors
Environmental Precautions: Prevent run-off to drains and waterways, inform authorities of larger spills
Cleanup Methods: Absorb with inert dry material (vermiculite, sand), shovel up and place in closed containers for disposal, wipe residue with damp cloth
Disposal: Collect spill in labeled waste drum for chemical waste removal, follow local environmental regulations
Decontamination: Wash area with mild detergent and plenty of water, avoid creating aerosols
Handling: Handle in fume hood or well-ventilated area, avoid all skin and eye contact, keep container tightly closed when not in use, no smoking, spark, or flame sources nearby
Storage: Store locked up in a cool, dry, fire-resistant area, away from acids, oxidizers, food and animal feedstuffs, keep away from direct sunlight
Incompatibilities: Strong acids, strong oxidizers, anhydrides, halogens
Special Requirements: Electrical equipment must be explosion-proof, clearly label storage locations, store in original or compatible containers
Engineering Controls: Use chemical fume hood and maintain adequate ventilation, keep eyewash station and safety showers accessible
Personal Protective Equipment: Splash goggles, long gloves (e.g. nitrile), lab coat or apron, face shield for large-scale handling
Respiratory Protection: If exposure limits may be exceeded, use organic vapor respirator or PAPR
Hygiene Measures: Wash hands and face after use, launder work clothes separately, remove contaminated clothes immediately
Occupational Exposure Limits: None established for 4-ethylmorpholine in many regions, default to general industry limits for similar amines
Appearance: Clear, colorless to pale yellow liquid
Odor: Amine-like, sharp odor
Odor Threshold: Low, irritant threshold is quickly reached
pH: Alkaline in solution
Melting Point: -40 °C
Boiling Point: 146 °C
Flash Point: 36 °C (97 °F)
Evaporation Rate: Moderate
Flammability: Flammable liquid
Vapor Pressure: 8 mm Hg @ 25 °C
Vapor Density: 3.7 (air = 1)
Relative Density: 0.906 g/cm³
Solubility: Highly soluble in water, mixes with alcohol and ether
Partition Coefficient: Log Kow: 0.2
Autoignition Temperature: 220 °C
Decomposition Temperature: Not specified
Viscosity: Thin, watery
Stability: Stable under recommended storage and handling conditions, unstable in presence of strong acids and oxidizers
Reactivity: Rapidly reacts with acid chlorides, strong oxidizers, can polymerize with anhydrides
Hazardous Decomposition: Burns to create potentially toxic gases (CO, CO2, NOx), corrosive vapors possible under fire
Conditions to Avoid: Sparks, open flames, heat, incompatible chemicals
Polymerization: Not likely under normal use
Container Materials: Avoid storage in copper, aluminum, or their alloys as amines can corrode them
Acute Toxicity: LD50 (oral, rat): 600 mg/kg, LD50 (dermal, rabbit): 650 mg/kg, vapors highly irritating
Symptoms: Skin burns, eye burns, cough, headache, sore throat, possible delayed lung edema
Chronic Effects: Prolonged exposure can cause dermatitis, respiratory tract damage, possible kidney or liver effects
Carcinogenicity: Not listed as known human carcinogen, limited long-term data
Sensitization: May irritate skin or respiratory tract in sensitives
Mutagenicity: Data lacking, use with caution
Reproductive Effects: No direct evidence, follow strict exposure controls
Ecotoxicity: Harmful to fish (LC50 lower than 100 mg/L), follows same pattern for invertebrates and aquatic plants
Persistence: Remains in soil and water for several months, not rapidly biodegradable
Bioaccumulation: Possibility considered low based on log Kow, but aquatic organisms can concentrate similar amines
Mobility: Moves easily in water, risk of leaching to groundwater
Other Effects: Toxicity to microorganisms can disrupt wastewater treatment if spilled in volume
Waste Methods: Dispose as hazardous chemical waste, never pour down drain or mix with drains from incompatible substances
Container Disposal: Triple rinse empty containers, puncture and send for chemical landfill or authorized incineration
Local Regulation: Check with your local/environmental agency, label all waste drums, keep compatible with other wastes
Incineration: Suitable for licensed hazardous-waste incinerators
UN Number: UN2735
UN Proper Shipping Name: Amines, liquid, corrosive, flammable, n.o.s. (contains 4-ethylmorpholine)
Transport Hazard Class: 8 (corrosive), 3 (flammable liquid)
Packing Group: II
Labels: Corrosive, Flammable
Marine Pollutant: Not designated under IMDG, but caution with aquatic contamination
Transport Precautions: Keep upright, sealed, segregate from food, acids
Special Provisions: Emergency procedures for spill or exposure listed on shipping documents, must carry SDS in vehicle
EU Legislation: Classified under CLP Regulation (EC) No 1272/2008, REACH registered, subject to workplace controls
US Regulations: TSCA listed, SARA Title III (Section 311/312): acute and fire hazard, no CERCLA reporting quantity
International: Listed in most major chemical inventories (Canada DSL, Australia AICS, Japan ENCS and ISHL, Korea ECL)
Labeling Requirements: GHS pictograms for flame, corrosive, exclamation mark, hazard and precaution statements
Local Authority Compliance: Users must check national and regional specific duties for storage, use, and disposal
