Product Name: 4-Chloro-7H-Pyrrole[2,3-d]Pyrimidine
Synonyms: None commonly recognized
Chemical Formula: C6H3ClN4
Molecular Weight: 166.57 g/mol
Recommended Use: Laboratory research chemical
Supplier: Sourcing information varies between chemical manufacturers
Emergency Phone: Listed by supplier; always keep local emergency contact numbers available
GHS Classification: Acute toxicity (Oral) Category 4, Skin irritation Category 2, Eye irritation Category 2A
Pictogram: Exclamation mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation
Precautionary Statements: Wash exposed skin thoroughly after handling, avoid eating/drinking during use, use personal protective equipment. Seek medical advice if exposure causes discomfort or symptoms develop.
Chemical Name: 4-Chloro-7H-Pyrrole[2,3-d]Pyrimidine
Content: ≥98% by weight
Impurities: Trace level by-products may occur depending on synthesis batch
CAS Number: 36821-58-2
General Advice: Remove contaminated clothing and rinse exposed area thoroughly
Inhalation: Move affected person to fresh air, support breathing, consult physician
Skin Contact: Rinse thoroughly with soap and water for at least 15 minutes, remove contaminated clothing, seek medical advice if symptoms persist
Eye Contact: Flush eyes gently with water for at least 15 minutes holding eyelids open, medical evaluation recommended
Ingestion: Rinse mouth thoroughly, do not induce vomiting, seek immediate medical assistance, monitor for symptoms such as stomach pain, headache, or malaise
Suitable Extinguishing Media: CO2, dry chemical powder, foam, water spray
Special Hazards: Emits toxic fumes under fire conditions (hydrogen chloride, nitrogen oxides)
Protective Equipment: Firefighters should wear full protective clothing, self-contained breathing apparatus
Other Advice: Cool containers with water spray from a safe distance, prevent fire run-off from entering drains
Personal Precautions: Wear protective gloves, goggles, laboratory coat, approved mask in confined areas
Environmental Precautions: Prevent release to soil, surface water or drainage system; spill must be contained
Methods for Clean-up: Absorb with sand or inert material, sweep up carefully, transfer to container for disposal
Ventilation: Use local exhaust in contaminated area to disperse vapors/dust
Decontamination: Wash spill site thoroughly after material pickup is complete
Handling: Use only with adequate ventilation, avoid breathing dust or vapors, avoid skin and eye contact, keep away from heat and open flames, wash hands thoroughly after use
Storage: Store in tightly closed container, in a cool, dry, well-ventilated place, keep away from incompatible substances such as strong oxidants and acids, protect from direct sunlight and moisture, secure against unauthorized use
Engineering Controls: Use fume hood or local exhaust, laboratory-scale procedures recommended
Respiratory Protection: NIOSH-approved respirator if dust or aerosols are generated
Skin Protection: Chemical-resistant gloves, lab coat
Eye Protection: Chemical splash goggles
Hygiene Measures: Do not eat, drink, or smoke while handling, always wash hands after use, remove contaminated clothing promptly
Appearance: Off-white to yellow crystalline powder
Odor: Odorless or faint chemical scent
pH: Not determined (not readily soluble in water)
Melting Point: Approx. 200-210°C
Boiling Point: Decomposes before boiling
Solubility: Sparingly soluble in water, soluble in organic solvents like DMSO and ethanol
Vapor Pressure: Not measured
Density: About 1.56 g/cm³
Partition Coefficient: Not available
Flash Point: Not established
Auto-ignition Temp: No reliable data
Decomposition Temp: May emit toxic gases at elevated temperatures
Chemical Stability: Stable under recommended storage conditions
Reactivity: Non-reactive at room temperature under normal use
Conditions to Avoid: Excessive heat, moisture, open flames
Incompatible Materials: Strong oxidizers, strong acids, strong bases
Hazardous Decomposition: Hydrogen chloride, nitrogen oxides released on thermal decomposition
Polymerization: Not known to undergo hazardous polymerization
Acute Toxicity: Harmful if swallowed (rat oral LD50 between 300-2000 mg/kg, data from structural relatives)
Skin Contact: Causes mild to moderate irritation
Eye Contact: May cause irritation, redness, and watering
Chronic Effects: Prolonged or repeated skin exposure may lead to dermatitis
Carcinogenicity: Not classified by IARC, no data suggesting carcinogenic potential
Mutagenicity: Not evaluated by standard mutagenicity assays
Sensitization: Not expected to produce allergic reaction, but handle with care
Target Organs: Data insufficient; general caution advised
Ecotoxicity: Limited data; avoid environmental release due to possible aquatic toxicity
Persistence and Degradability: Not readily biodegradable, can persist in surface waters
Bioaccumulation Potential: No evidence of significant bioaccumulation
Mobility in Soil: Moderately mobile if released; low water solubility limits rapid dispersion
Other Environmental Hazards: No known ozone-depleting potential; minimize release to environment
Waste Disposal Methods: Incinerate or dispose of as hazardous chemical waste in accordance with local, regional, and national regulations
Contaminated Packaging: Empty containers must be triple-rinsed, defaced, and disposed as hazardous waste
Special Precautions: Avoid disposal via regular wastewater or general waste systems; consult regulations before bulk disposal
UN Number: Not classified for transport as dangerous goods by ADR/RID/IMDG/IATA
Proper Shipping Name: Not regulated
Hazard Class: None assigned
Packing Group: None assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Ensure well-sealed packaging, protect from damage and moisture during transport, keep away from incompatible substances
TSCA Status: May not be listed explicitly, check with supplier
REACH Status: Registration status may vary; consult supplier/European Chemicals Agency
OSHA Status: Not specifically regulated
SARA Title III: Not classified as extremely hazardous
California Proposition 65: Not listed
Other Regulations: Users must comply with all applicable regional, national, and local laws regarding handling, storage, and disposal
