Product Name: 4.5.6.7-Tetrahydrothiophene[3.2.0] Pyridine Hydrochloride
Chemical Formula: C7H10NS·HCl
Synonyms: Tetrahydrothiophene pyridine hydrochloride, Pyridinium, tetrahydrothiophene hydrochloride
Manufacturer: Supply information according to supplier
CAS Number: (Contact supplier for number, as public databases lack a common identifier)
Recommended Use: Laboratory chemical, intermediate for organic synthesis, specialty materials research
Restrictions: Not for use in food, drug, or household contexts
GHS Classification: Acute Toxicity (Oral) Category 4, Skin Irritant Category 2, Eye Irritant Category 2A, Specific Target Organ Toxicity (Single Exposure) Category 3
Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid breathing dust or vapor, wash thoroughly after handling, wear protective gloves and eye protection, do not eat or drink during use
Other Hazards: Irritating vapor, may cause release of toxic fumes if heated, not listed as carcinogen by IARC, NTP, or OSHA
Chemical Name: 4.5.6.7-Tetrahydrothiophene[3.2.0] pyridine hydrochloride
Concentration: >98% by weight
Impurities: Minor organic byproducts (<2%), HCl residual traces
Ingredient Disclosure: No known hazardous stabilizers or additives, hydrate content negligible
General: Move affected person away from source and into fresh air
Inhalation: Move to fresh air, provide oxygen if breathing is difficult, seek medical attention for persistent symptoms
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water for 15 minutes, medical attention if irritation continues
Eye Contact: Rinse eyes gently with water for 15 minutes while holding eyelids apart, remove contact lenses if present, seek ophthalmologist aid
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, immediate hospital treatment important
Most Important Symptoms: Burning, redness, coughing, sore throat, stomach upset, tearing of the eyes
Suitable Extinguishing Media: Water spray, dry chemical, alcohol-resistant foam, CO2 extinguishers
Unsuitable Media: Do not use strong water jets
Specific Hazards: Toxic and irritating gases released during combustion — these may include carbon oxides, nitrogen oxides, sulfur oxides, hydrogen chloride
Protective Equipment: Firefighters should wear full protective gear, including self-contained breathing apparatus
Advice for Firefighters: Avoid inhalation of fumes, cool containers with water from a distance, ensure proper ventilation after fire
Personal Precautions: Avoid contact with skin, eyes, and clothing, use appropriate personal protection, ventilate area
Emergency Procedures: Evacuate unnecessary personnel, prevent dust or vapor formation, stop spill if safe
Environmental Precautions: Prevent entry to soil, drains, and watercourses, contain spill
Clean-Up Methods: Absorb with inert material (earth, sand, vermiculite), transfer to chemical waste container, decontaminate surface with soap and water, dispose per Section 13
Precautions for Safe Handling: Work in well-ventilated space or under chemical fume hood, minimize dust creation, avoid breathing vapors, keep away from incompatible substances such as oxidizers
Hygiene Practices: Wash hands before eating, drinking, or smoking after use, remove contaminated clothing
Conditions for Safe Storage: Store in tightly closed containers in cool, dry, well-ventilated area, protect from heat and moisture, keep away from food and feedstuffs
Incompatibility: Strong oxidizing agents, reducing agents, alkali metals, moisture-sensitive materials
Exposure Limits: No specific OSHA or ACGIH limits, minimize exposure as general rule
Engineering Controls: Chemical fume hood or equivalent engineering controls necessary
Personal Protective Equipment: Nitrile or neoprene gloves, safety goggles or face shield, lab coat or chemical apron
Respiratory Protection: NIOSH/MSHA-approved respirator if exposure limit unknown or ventilation lacking
Environmental Controls: Prevent spills from leaving work area, use properly functioning air filtration for exhaust
Physical Form: Crystalline solid
Color: White to off-white
Odor: Slight, sulfur-like
Molecular Weight: Approx. 177 g/mol
Melting Point: 210–215°C (decomposition possible)
Boiling Point: Not readily measured (decomposes)
Solubility: Soluble in water, ethanol, slightly soluble in organic solvents
pH (aqueous solution): Acidic, about 2.5–3.5
Vapor Pressure: Negligible
Density: Approx. 1.25 g/cm3
Flammability: Not easily combustible, may emit toxic vapor if burned
Partition Coefficient: Not available
Evaporation Rate: Not volatile under normal conditions
Chemical Stability: Stable at ambient temperatures in tightly closed containers
Conditions to Avoid: Humidity, excessive heat, open flames, static discharge
Materials to Avoid: Strong acids, bases, oxidizers, reducing metals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, hydrogen chloride, sulfur oxides, nitrogen oxides
Polymerization: Not expected under normal handling or storage
Acute Toxicity: Oral LD50 (rat) approximately 500–750 mg/kg (estimated from structure-analog data)
Routes of Exposure: Inhalation, skin/eye contact, ingestion
Symptoms: Irritation of mucous membranes, cough, skin reddening, eye discomfort, stomach pain with ingestion
Chronic Effects: No published reports of chronic toxicity, repeated exposure may cause persistent dermatitis or respiratory irritation
Carcinogenicity: No evidence or classification available
Other Data: Not mutagenic or teratogenic based on current information; minimize exposure as data is incomplete
Environmental Toxicity: Not thoroughly studied, avoid uncontrolled release
Aquatic Toxicity: Potentially harmful by analogy to related heterocyclic amines, estimate LC50 for fish <100 mg/L
Persistence/Degradability: Product likely degrades slowly, consult environmental authorities for safe practice
Bioaccumulation: Not expected to bioaccumulate extensively
Mobility in Soil: Water solubility suggests possible migration in soil or groundwater
Precautions: Keep out of watercourses and drains
Disposal Methods: Dispose according to federal, state, and local environmental regulations
Container Disposal: Rinse containers before recycling or discarding, deface label to prevent misuse
Special Precautions: Do not flush into sewers, avoid disposal in municipal landfill without treatment, incinerate in chemical incinerator equipped with afterburner and scrubber, consult hazardous waste specialist
UN Number: Not assigned, consult transport authority if large-volume shipment
Proper Shipping Name: Not regulated for small samples, label as corrosive solid if above threshold
Transport Hazard Class: Most similar to Class 8 (corrosive) if packing group applies
Packing Group: III (estimate based on hazard profile)
Special Transport Notes: Secure packaging, prevent movement, avoid breakage, keep away from incompatible materials
Marine Pollutant: No data, suggest label as environmentally hazardous if transported by sea
TSCA Status: Not listed specifically, research or laboratory use only
SARA 313: Not a regulated substance
California Prop 65: Not classified
EINECS/ELINCS: Registration for industrial or research use, confirm status with importer/exporter
Other Standards: Follow good laboratory practices, comply with local, regional, federal guidelines for hazardous chemicals
Labelling Requirements: Clearly label with chemical name, hazard pictogram, precautions on all containers
Training: Ensure handlers understand chemical risks and emergency measures
