Material Safety Data Sheet: 4-[3-(1-Naphthylamino)Propyl]Morpholine

Identification

Product Name: 4-[3-(1-Naphthylamino)Propyl]Morpholine
Chemical Family: Naphthylamine derivatives
Synonyms: N/A
CAS No.: 61306-59-4
Recommended Uses: Research, chemical analysis, potential pharmaceutical intermediate
Manufacturer Information: Manufacturer address, emergency contact, phone number available on label

Hazard Identification

Classification: Harmful if swallowed, irritating to eyes and skin, suspected mutagen
Signal Word: Warning
Hazard Statements: May cause eye, skin, and respiratory tract irritation; harmful if absorbed through skin; may cause genetic defects with chronic exposure
Pictograms: Exclamation mark, health hazard
Precautionary Statements: Avoid breathing dust/fume; wear protective gloves, clothing, and eye protection; wash thoroughly after handling; do not eat, drink, or smoke while using
Other Hazards: Combustible dust formation possible; environmental persistence, potential hazard to aquatic life

Composition / Information on Ingredients

Chemical Name: 4-[3-(1-Naphthylamino)Propyl]Morpholine
Percentage: ≥98% by weight
Impurities: Trace morpholine derivatives, solvent residues (check analytical certificate)
Molecular Formula: C17H20N2O
Molecular Weight: 268.36 g/mol

First Aid Measures

General Advice: Remove contaminated clothing, move affected person to fresh air
Eye Contact: Rinse immediately with plenty of water, hold eyelids open for at least 15 minutes, seek medical attention
Skin Contact: Wash skin with soap and water for at least 15 minutes; if irritation develops, call a doctor
Inhalation: Move person to well-ventilated place, monitor breathing, administer oxygen if needed, seek medical advice
Ingestion: Rinse mouth, do not induce vomiting, get medical help

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: Direct water stream can scatter material
Special Hazards: Releases toxic fumes of nitrogen oxides, carbon monoxide, and carbon dioxide when burned
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Control runoff to prevent entry into drains and waterways; move containers from fire area if it can be done safely

Accidental Release Measures

Personal Precautions: Evacuate unprotected personnel, ventilate area, avoid inhalation and skin contact
Environmental Precautions: Prevent entry into sewers and waterways, contain with earth or inert material
Methods for Cleaning Up: Collect spillage using sealed containers, clean remainder with solvent-soaked absorbent, dispose as hazardous waste
Reference to Other Sections: Use PPE as detailed in Section 8

Handling and Storage

Precautions for Safe Handling: Avoid contact with eyes, skin, and clothing; avoid breathing vapors, keep containers tightly closed in use
Conditions for Safe Storage: Store in cool, dry, well-ventilated area, away from incompatible substances (strong oxidizers, acids), keep away from heat and ignition sources
Incompatible Materials: Strong acids, oxidizing agents, reducing agents
Storage Class: Chemical storage, away from food and drink

Exposure Controls and Personal Protection

Engineering Controls: Chemical fume hood, eye wash stations, safety showers
Respiratory Protection: Approved respirator if dust or vapor concentrations are high
Hand Protection: Chemical-resistant gloves (nitrile recommended)
Eye/Face Protection: Chemical splash goggles, face shield (for large volumes)
Skin and Body Protection: Lab coat, long sleeves, closed-toe shoes

Physical and Chemical Properties

Appearance: Off-white or pale yellow crystalline solid
Odor: Faint amine-like odor
Melting Point: 114–118 °C
Boiling Point: Not available
Solubility: Slightly soluble in water; soluble in ethanol, DMSO, acetone
Density: ~1.2 g/cm³
pH: Not determined
Vapor Pressure: Very low at room temperature
Partition Coefficient: Not available
Auto-ignition Temperature: Not available
Flash Point: >150 °C (closed cup - estimate)

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Reactive with strong acids and oxidizers
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, toxic fumes
Conditions to Avoid: Excess heat, exposure to moisture or light, incompatible materials

Toxicological Information

Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Effects: Causes irritation to skin, eyes, and mucous membranes
Chronic Effects: Possible mutagenic effects with chronic exposure
Toxicity Data: No specific LD50 values publicly available, based on similar morpholine derivatives expect moderate toxicity
Symptoms: Redness, itching, respiratory discomfort, nausea, headache possible
Sensitization: Not expected under normal laboratory conditions
Carcinogenicity: Not listed by IARC, NTP, OSHA as a confirmed carcinogen

Ecological Information

Ecotoxicity: Toxic to aquatic organisms at moderate concentrations
Persistence and Degradability: May persist in soil and water, limited biodegradability
Mobility: May leach into groundwater in the case of a large spill
Bioaccumulation: No bioaccumulation potential data available; structurally similar chemicals show low-moderate accumulation
Other Adverse Effects: Not expected to cause significant ozone depletion or global warming effects

Disposal Considerations

Waste Treatment Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber, observe all federal, state, and local environmental regulations
Contaminated Packaging: Dispose as hazardous waste; do not reuse packaging
Special Precautions: Do not allow material to enter drains, surface water, or soil

Transport Information

UN Number: Not regulated under most transport regulations
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not a marine pollutant for transport purposes
Special Precautions for User: Use secondary containment during transport to prevent leaks or spills

Regulatory Information

US Regulations: Not listed on SARA Title III, not subject to CERCLA reporting
TSCA Status: Not listed; labeling as research chemical recommended
EU Regulations: Not classified under EC 1272/2008 (CLP Regulation); use as laboratory chemical only
Other Regulations: Handle according to local, national, and international chemical safety regulations; workplace hazardous substances registration required in some regions; ensure staff training and communication of hazards; maintain appropriate documentation and labeling in all storage and transit environments