Decades ago, as chemists raced to create stronger, more selective molecules for medical and industrial innovation, researchers stumbled across amine derivatives that could bridge old gaps in synthetic chemistry. 4-[3-(1-Naphthylamino)Propyl]Morpholine took shape during an era hungry for unique structures that balanced aromatic and heterocyclic moieties, promising new options for both laboratory and practical applications. Early syntheses often struggled with purification and yield issues. Persistence paid off, and labs eventually pushed the preparation toward higher purity, setting the stage for larger-scale studies. Throughout the 1980s and 1990s, as nucleophilic aromatic substitution and amine linking techniques advanced, this compound started to see publication in specialized journals. Researchers kept a close eye on naphthyl-based amines, not only for their reactivity, but for their growing appeal in pharmacological screens. Chemical libraries swelled with variations, and 4-[3-(1-Naphthylamino)Propyl]Morpholine drew attention for its versatility and stable properties.
This molecule stands out for its unique fusion of a morpholine ring with a propyl chain linking to a naphthylamino group. The design introduces both aromatic and heterocyclic influences, leading to interesting reactivity patterns and biological compatibility. Most suppliers offer the compound as a solid, crystalline powder. Careful curation of raw material and source documentation reflects tightening regulatory expectations, especially for pharmaceutical and agrochemical intermediates. Those in research see this substance as a tool, not just a commodity, since its structure means easy tuning of both polarity and solubility.
4-[3-(1-Naphthylamino)Propyl]Morpholine shows off as a pale powder under ambient conditions, with a melting point leaning into the higher range for amine derivatives—measured near 102–105°C. The molecule dissolves well in moderate-polarity solvents—typical choices include dimethyl sulfoxide, methanol, and chloroform. Its naphthalene ring brings a surprising degree of stability, while the morpholine end tolerates exposure to slightly acidic or basic conditions without quick decomposition. In practice, UV-visible absorbance features reflect the aromatic system, letting analytical labs nail down its presence with reasonable sensitivity. From a reactivity perspective, the propyl linker buffers the two functional regions, letting the molecule handle both electrophilic and nucleophilic reagents, given moderate temperatures and careful stoichiometry.
As distribution chains tighten up, thorough specification sheets follow every batch. Chemists can expect clear data on molecular weight, typical purity ranges (often exceeding 98% by HPLC), moisture content, IR and NMR spectra, and known trace impurities—primarily from ring substitution byproducts or incomplete alkylation. Shipping documents flag the substance with its full IUPAC name and CAS registry, along with key hazard symbols. More and more, QR-coded batch records tie origin, testing, and shelf life together in one place. Detailed SDS forms provide guidance, especially for those in small-scale synthesis labs who value certainty over guesswork. Labs use these forms not only to gauge handling risks, but also to inform waste disposal routines.
Most syntheses start with 1-naphthylamine as a base, anchoring the compound's aromatic identity. The core sequence brings this starting amine into reaction with a 3-chloropropyl intermediate, either as a free halide or tosylated leaving group, under nucleophilic substitution. After driving the alkylation to completion—sometimes under phase-transfer conditions to coax stubborn substrates—researchers purify the crude product through crystallization or flash chromatography. For the final step, morpholine enters as a nucleophile, displacing the remaining leaving group. Catalysts help drive the substitution without over-alkylating fragile amine sites. Each step brings control challenges, especially if the substitution runs hot or with excess base, since the naphthyl core doesn't always play nicely under harsh conditions. Final purification strips out any side-products before analytical confirmation seals the batch's fate.
The structure of 4-[3-(1-Naphthylamino)Propyl]Morpholine supports a handful of key derivatizations. Electrophilic aromatic substitution adds to the naphthyl ring, giving options for halogenation or sulfonation when tailoring physical properties. On the other end, the morpholine ring resists attack, but can accommodate acylation or N-oxidation, leading to potential prodrug or solubility-modifying derivatives for pharmaceutical use. The propyl chain holds up under mild conditions, so selective modifications target either end without risking backbone cleavage. Under reductive amination, scientists sometimes swap the naphthyl group for other aryls without scrapping the morpholine scaffold. Altogether, the molecule resists degradation under strong light or moderate heat, giving researchers flexibility during reaction planning.
Beyond its full chemical designation, suppliers often use trade-friendly monikers to cut through the complexity. “Naphthylpropylmorpholine” crops up frequently in internal databases. Older literature might call out propyl-naphthyl morpholine analogues or shorthand codes like NPM-13, depending on the screening campaign driving interest. Proper labeling traces these alternate names back to the definitive IUPAC string, since confusion in order handling can send a research effort sideways in a hurry. Institutional settings now require both common names and the CAS registry number on container labels and carton documentation to prevent inventory slip-ups. Some catalogs flag analogs side-by-side, encouraging comparative testing and minimizing ordering errors.
Anyone handling 4-[3-(1-Naphthylamino)Propyl]Morpholine needs to know both best practices and red flags. Being an amine derivative, it sometimes releases pungent vapors if mishandled, and skin or eye contact can bring irritation—so gloves and splash-proof goggles sit on every benchtop. Storage rules push for dry, cool cabinets, away from oxidizers or strong acids, to lock down unwanted reactions. Labs run regular training covering both accident prevention and spill response, since even small leaks can disrupt productive work. Waste handling means more than just binning leftovers—spent reagents and rinse solutions wind up in labeled containers for professional disposal. Regulatory audits check that each package meets both local workplace safety rules and international transport requirements, matching paperwork up with on-the-shelf practices. Reliable suppliers back every sale with an up-to-date SDS, containing not only GHS-compliant hazard coding but direct phone contact for emergency guidance.
Its naphthylamino group makes this compound attractive for drug discovery, especially in CNS-targeted screens. Aromatic amines in this family often compete in receptor binding assays, targeting neuroactive pathways. The propyl-morpholine side chain draws out water solubility without dumping aromatic stability, so chemists use it to probe receptor selectivity or metabolic stability. Industry also eyes the molecule for specialty dye intermediates and as a building block in materials chemistry. Some agricultural labs work it into tests for pest control agents, betting that the amine and ether elements disrupt insect neurochemistry in ways that older molecules can’t. Those in academia explore its behavior in sensors, where chromophoric properties and proton-binding behavior make for clever detection schemes. I once saw a project pivot from classic naphthylamines to this morpholine hybrid, after realizing its lower volatility and improved handling eased both student safety and project reproducibility. Every year, new journal papers push for deeper insights, with citations stacking up across both pharmacology and organic synthesis circles.
As fresh chemical libraries launch with structure-based design, this compound’s hybrid nature encourages a blend of old-school screening and big data-driven prediction. Medicinal chemists test a library’s naphthylamino morpholines in models for brain-penetrant drugs, where solubility and receptor docking go hand-in-hand. On the industrial side, R&D groups explore greener synthesis by swapping harsh halide chemistry for more selective catalysts. Process engineers have succeeded at scaling up production with less solvent, lower waste, and more reliable yields, often inspired by lessons from pilot batches or academic publications. Ongoing collaborations between suppliers and end-users keep refining not just the chemistry, but the safety and analytics as well. Teams now lean on powerful NMR and mass spectrometry suites to validate intermediates in real time, cutting development cycles and raising confidence before scale-up. The molecule’s sturdy framework has also prompted researchers to chase modifications aimed at PET imaging agents and advanced materials, broadening the compound’s relevance beyond simple synthetic chemistry.
Toxicologists approach 4-[3-(1-Naphthylamino)Propyl]Morpholine with an eye toward both acute and chronic effects. Early screens focused on cytotoxicity against standard mammalian cell lines, with results showing moderate risk at high exposure levels—most often at concentrations unlikely in routine lab use. Animal models show typical dose-responses for amines with aromatic features: liver enzymes process the compound via oxidation and conjugation, while the morpholine ring leaves most metabolic pathways unblocked. Some regulatory agencies request longer-term bioaccumulation studies before greenlighting new drug candidates that use this backbone. Environmental scientists also track solubility and breakdown byproducts, ensuring that production sites handle run-off carefully and monitor for any long-chain amine residues in discharge water. In my experience, research protocols lean toward caution but don’t treat this molecule as unusually threatening—standard ventilation, glove use, and surface cleaning have proved more than sufficient for day-to-day use. Still, as cross-contamination risks rise with more complex chemical blends, new studies delve into interactions with other aromatic amines, hunting for additive toxic effects or rare metabolic surprises.
Those working at the intersection of drug design and fine chemical manufacturing increasingly look to hybrid molecules like 4-[3-(1-Naphthylamino)Propyl]Morpholine. Its structure bridges useful worlds: aromatic stability, flexible modification, reliable solubility, and decent metabolic stability. Drug discovery keeps hunting for better CNS actives that dodge transporter blocks and metabolic traps, a race that often sends chemists back to subtly revised scaffolds like this one. In my own work, scaffolds that survive both the harsh scrutiny of regulatory review and the rough-and-tumble of pilot-scale synthesis build trust in the entire class. Academic labs focusing on green chemistry sit poised to push new catalysts and greener purification tricks, trying to cut energy and material usage without sacrificing access to useful building blocks. Advances in rapid screening and machine learning-guided optimization keep raising the bar, promising continued relevance as both old and new application areas expand. As long as research budgets back chemists willing to tinker and improve, compounds with the adaptable, reliable profile of 4-[3-(1-Naphthylamino)Propyl]Morpholine stand to gain ground, whether in tomorrow’s medicines, innovative materials, or as the backbone for still undiscovered breakthroughs.
Chemistry never feels more real than when you look at a structure on paper and start putting together each atom’s role. 4-[3-(1-Naphthylamino)Propyl]Morpholine is quite a mouthful, yet its layers actually tell a clear story. The backbone includes morpholine, a well-known heterocyclic ring. Picture morpholine as a six-sided loop, four carbons linked with oxygen and nitrogen rounding it out. This structure often pops up in pharmaceuticals thanks to its flexible, polar nature. It gives molecules a boost for water solubility, which can help with absorption in the body.
From the fourth carbon on that ring, a propyl chain jets out—a simple three-carbon line. Attached to the end sits a 1-naphthylamino group. Here, “1-naphthyl” points out that the amine hooks up to the naphthalene ring system at the first carbon. Naphthalene brings two fused benzene rings, sharing a pair of carbons and creating stability with aromaticity. Organic chemists love naphthalene’s rigid structure; it shapes how drugs interact with biological targets through stacking or hydrophobic forces.
The “amino” part is just a nitrogen attached directly to the naphthalene. This piece can be a game-changer, since it can form hydrogen bonds or serve as a site for chemical reactions in the body. It’s almost like plugging a power tool into a special outlet—suddenly more jobs become possible.
Getting to know the actual shapes and connections in molecules like 4-[3-(1-Naphthylamino)Propyl]Morpholine matters beyond simple curiosity. While working as a medicinal chemist, I learned quickly that structure isn’t just an abstract exercise. A morpholine ring can turn a borderline-active compound into something that zips through the bloodstream efficiently, dodges metabolic breakdown, or binds tightly to a certain receptor. Some drugs out on pharmacy shelves, including big names in cancer treatment and depression, borrow heavily from morpholine scaffolds.
Adding a naphthylamino group—no easy feat with bulky rings and amines involved—often means a step up in potency or specificity. Aromatics, especially fused systems like naphthalene, interact with the building blocks of biology: proteins, DNA. They snuggle into enzyme pockets, or slip between base pairs like a card in a deck. Medicinal chemists hunt for this balance, aiming for molecules that hit disease targets and skip the healthy ones.
Whether a structure helps or hurts depends on small tweaks. Adding—or moving—a single atom changes how the body sees a whole drug. Naphthalene often raises red flags for toxicity, but careful design and functional group protection can make the difference. Researchers lean on computational models and real-world testing to guide every change. The process never ends with a skeletal formula.
High-level synthesis always produces a mix of science and art. Building 4-[3-(1-Naphthylamino)Propyl]Morpholine pulls together reactions like nucleophilic substitution and amine coupling. Lab teams chase purity and yield, watching out for unwanted byproducts. Once they’ve got it, the next questions rise up: Can this molecule block harmful enzymes? Ease chronic pain? Its pieces hint at both promise and risk.
A smart future leans on structure-based design. That means feeding structures like this into databases, comparing them to what’s been tested, and running custom screens for new drug candidates. Collaborations between chemists, pharmacologists, and data scientists shape pipelines that feed off every new compound’s structure. Understanding every part of complex molecules like 4-[3-(1-Naphthylamino)Propyl]Morpholine pushes discovery forward—not just on paper, but all the way to new hope for patients.
Not every chemical has a flashy headline, but some still play a behind-the-scenes role in moving science and industry forward. One of these quietly significant compounds is 4-[3-(1-Naphthylamino)Propyl]Morpholine, a mouthful that finds its way into several layers of life sciences and manufacturing. My own work in academic chemistry labs showed me how compounds like this can mean the difference between a stalled experiment and a breakthrough.
Researchers in drug discovery always look for new scaffold molecules to design better medicines. 4-[3-(1-Naphthylamino)Propyl]Morpholine fits this role. Its dual structure—a morpholine ring linked to a naphthyl group—gives it chemical flexibility and the chance to interact with a wide range of biological targets. Medicinal chemists run it through screens to see if it can act as a prototype for drugs aimed at neurological or oncological disorders. A study out of India suggested that related morpholine derivatives showed promise against certain cancer cell lines. Companies in biotech often synthesize dozens of slight variations using molecules like this, hunting for the one that blocks a disease pathway or binds a mutant protein just right.
Material scientists look for chemical building blocks that bring both stability and the chance to tune properties. I spent semesters watching my colleagues use naphthylamines as starting points to make luminescent polymers and new dyes. 4-[3-(1-Naphthylamino)Propyl]Morpholine’s combination of naphthyl and morpholine groups makes it attractive for this. By inserting it into polymers or specialty coatings, researchers can affect color, fluorescence, and resistance to degradation. These are features in demand across industries making sensors, displays, or solar panels.
A lot of lab time gets spent making intermediates—a kind of relay racer in the marathon from raw chemicals to complex products. 4-[3-(1-Naphthylamino)Propyl]Morpholine often serves as one of these chemical hand-offs. Skilled synthetic chemists use it as a linker or precursor, setting up reactions that might swap out a part of its structure to arrive at hard-to-reach molecules. Think of it as a reliable puzzle piece in multi-step organic synthesis, especially when seeking nitrogen-rich scaffolds.
Safety always counts. Few outside the profession realize how strict the handling protocols are for specialty chemicals, especially those with aromatic amines. In the labs I worked in, safety data sheets for compounds like 4-[3-(1-Naphthylamino)Propyl]Morpholine were always up-to-date, and protective gear never stayed on the shelf. Education around responsible chemical use makes a difference. To address possible risks, some companies design molecules for easier degradation after use, or swap in less persistent functional groups. Regulators and researchers both bear the burden of keeping these efforts transparent.
Colleges and universities don't just see chemicals like this as research tools—they use them to train the next generation of scientists. I remember guiding students through reactions using similar compounds, watching them shape skills and learn to ask good questions about why and how a molecule matters. By openly sharing case studies and data, educators can connect textbook learning to real-world discovery.
Walking into a lab, you get used to seeing long chemical names. One of the less familiar ones—4-[3-(1-Naphthylamino)Propyl]Morpholine—doesn’t show up in most households, but could appear in research settings, chemical manufacturing, or specialty industries. Names like this tell a story about the way chemists tweak molecules to chase specific effects, but behind every tweak, real people interact with the substance.
Chemicals built on a naphthyl backbone—such as in this compound—often catch attention for two reasons: their stability in certain reactions, and their tendency toward tougher toxicity profiles. Aromatic amines and morpholine rings have a track record in toxicology; many are known irritants, some have made health headlines for much worse. Research on 4-[3-(1-Naphthylamino)Propyl]Morpholine itself appears thin, but the chemical family and structural features ring some alarm bells for occupational safety specialists.
People have learned, sometimes painfully, that invisible dangers can call for the most respect. Aromatic amines have been linked to skin sensitization, allergic reactions, and, with repeated exposure, possible carcinogenic effects. Morpholine derivatives have earned regulatory red flags in certain countries based on their potential for liver or kidney damage after extended contact. Mix naphthylamino and morpholine into one molecule, and the reasonable approach is to proceed with caution.
Nobody likes the hassle of gloves or goggles, but workers owe it to themselves and families to respect the legacy of chemical injuries and exposures. My years working near organic syntheses taught me a strict rule: treat unknowns as potential hazards until clear, peer-reviewed data says otherwise. Dermal exposures are the heavy hitter with aromatic amines—protective gloves (nitrile, not latex), eye shields, and good ventilation are a baseline, not an option.
Even the waste shouldn’t get casual treatment. Disposal routes for amines and morpholines sometimes trigger expensive concerns for environmental safety; wastewater regulators want to know these chemicals won’t slip into streams. Anyone in charge of disposal should coordinate with a hazardous waste specialist who knows what this molecule can do in water, soil, or air.
It’s easy to trust a datasheet, but with rare or new compounds, mistakes can creep in. If I can’t pull up published, robust toxicology on a material like 4-[3-(1-Naphthylamino)Propyl]Morpholine, I ask suppliers for full safety documentation or look at structural alerts from reputable chemical authorities. Getting lazy with secondary labelling or leaving open containers around is how accidents happen. Clear hazard communication—especially for new lab workers or contractors just passing through—builds a culture where safety isn't a guess.
Skepticism pays off with under-researched chemicals. Earning trust means giving people clear facts and transparent risk assessments. Labs and manufacturers win by shaping simple, habit-forming protocols that ask, “What’s my route of exposure? What happens if something spills? Can this be replaced with a less worrisome alternative?” If a material like this stays on the bench, every handler benefits from regular, honest safety drills and quick-access emergency gear. Quality of life isn’t just about what you make, but how you protect those making it.
Anyone who’s ever worked with fine chemicals knows that safe storage does more than keep a lab organized. It protects the material, the people, and the work itself. With compounds such as 4-[3-(1-Naphthylamino)Propyl]Morpholine, a little know-how about conditions keeps unwanted surprises to a minimum. Leaving a chemical out or storing it poorly doesn’t just waste money; it creates risk and reduces reliability of results. Once I saw a colleague lose weeks of research because a bottle spent weekend hours near a heat source. That’s no way to run a lab—frustrating and completely avoidable.
This compound typically calls for storage at room temperature, far from freezing or heat. Find a spot between 15°C and 25°C, well away from direct sunlight or radiators. Light and heat invite breakdown. A storeroom with stable temperature, controlled humidity, and limited access prevents most common issues like caking, oxidation, or weird color changes. Chemicals like this one stay in top condition inside airtight, amber-glass bottles. Years ago, most labs made do with generic containers, but opaque, sealed options keep out light and air better and cut down on degradation.
I remember a mistake from my early lab days—grabbing the wrong bottle from a poorly labeled shelf. Since then, I’ve never ignored the value of good labeling and separation. Mark the date received, the supplier, and expiration clearly. Keep labels facing out and always return containers to the same spot. Cross-contamination between similar-looking organics spells trouble for both safety and research outcomes. Regular checks for leaks, residue, or crystalline deposits have saved me more than once from tossing out a batch of solvent-contaminated reagents.
Air and moisture love to sneak into containers and change your chemical before you know it. Even if a product looks stable, oxygen or water vapor can kick-start reactions. Every use, seal the cap tight, ASAP. Even the act of leaving a cap off during a phone call can steer a product toward impurity or an unsafe state. Dry conditions in the storeroom matter—a desiccator cabinet can make a big difference if you share a humid environment. I’ve seen projects in coastal labs lose value due to dampness ruining sensitive organics. Choosing sealed cabinets and double-checking the tightness of every closure helps maintain integrity.
Never store morpholine derivatives beside strong acids, oxidizers, or flammable solvents. Accidents in labs often stem from overlooked shelf proximity rather than single-use mishaps. Any spill or reaction can quickly escalate where volatile materials sit together. Secure incompatible substances in separate cabinets and refer to a chart if uncertain. For new staff, regular walk-throughs help them internalize safe storage patterns that protect both them and the sample supply. I’ve seen experienced researchers slip up on this—sometimes, routine and confidence override caution unless the entire team stays vigilant.
A well-planned storage scheme saves time and protects your investment. Using secondary containment, spill-proof shelving, and strict cleanup routines, teams reduce accident chances and boost reliability. In my experience, teams that commit to routine checks and basic care rarely face emergencies. Assign responsibility for monitoring inventories and condition reports, so nothing falls through the cracks. Shared knowledge and mutual accountability go further than any single policy.
If you spot cloudiness, unusual odor, or sediment, segregate the bottle right away and request expert assessment before use. Keep a log of storage temperature fluctuations and incidents—a simple sheet on the wall does the job in most labs. Don’t hesitate to call the supplier’s technical support for clarification; good vendors stand by their storage recommendations, and their advice can prevent costly errors. The best labs I’ve worked with treat storage as central to quality—not as an afterthought once the experiments begin.
No lab technician wants to gamble with impure chemicals, especially with specialty compounds like 4-[3-(1-Naphthylamino)Propyl]morpholine. Purity isn't just a marketing term; it plays a central role in reproducibility, safety, and sheer value in pharmaceutical and materials research. From what I’ve learned navigating supply catalogs and technical teams, top suppliers consistently keep the minimum assay above 98%. This translates to very limited contaminants and trace impurities—something demanded by anyone performing advanced synthesis or drug development.
The main analytical approach for confirming purity involves high-performance liquid chromatography (HPLC). HPLC helps scientists check if the main peak (your desired product) stands head and shoulders above any side products. These test reports usually back up their purity claims, so the buyer isn’t left guessing about what’s inside the bottle. Besides HPLC, nuclear magnetic resonance (NMR) and mass spectrometry results often follow. Both provide reassurance that the morpholine ring, the naphthalene backbone, and all key groups landed where they belong.
It’s easy to promise high purity on paper, but the story deepens once you inspect full specifications. Reliable suppliers share full datasheets outlining not just minimum purity, but allowable water content, residual solvent limits, and heavy metal contamination. The water content, for instance, impacts both storage and downstream chemistry. Most reputable suppliers keep moisture below 0.5%, using Karl Fischer titration to confirm numbers. I once worked with a batch that exceeded this water limit—the reactions turned out sluggish. After switching to a drier batch, conversions promptly improved.
Residual solvents present another headache; lingering ether or alcohol traces might skew toxicology or alter the product’s shelf life. Most analysts look for solvent levels below 200 ppm. Heavy metal content routinely sits below 10 ppm. These cutoffs match pharmaceutical requirements and regulatory guidelines in most countries, which ensures researchers don’t introduce invisible hazards into sensitive reactions.
Lab heads who order gram or kilogram lots prefer certifications. Documentation like Certificates of Analysis (CoA) and Safety Data Sheets (SDS) always follow each batch. CoAs typically display batch-reported purity, individual impurity peaks, water content, and sometimes even exact method setups used in confirmation. Regulatory requirements in the US and EU demand such transparency, and many buyers won’t proceed without it.
Product traceability is just as important as the numbers on the sheet. Trustworthy suppliers log source lots, track raw materials, and provide documentation dating back several years. If there’s a recall or deviation, researchers can trace back to where things may have gone wrong. During my early years in the lab, we ran into an unknown impurity showing up late in a biological assay. Trawling through batch records helped pinpoint a supplier switch as the culprit—a lesson in why traceability isn’t bureaucratic busywork but solid, daily risk management.
For research groups looking to buy 4-[3-(1-Naphthylamino)Propyl]morpholine, a checklist pays off: demand a recent CoA, review full impurity breakdowns, double-check moisture limits, and confirm regulatory compliance. Build partnerships with suppliers that answer technical questions and provide access to archived analysis reports. Being fussy about documentation saves headaches long after the order arrives. It means less troubleshooting, steadier research, and a safer route to real discovery.
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| Names | |
| Preferred IUPAC name | 4-[3-(Naphthalen-1-ylamino)propyl]morpholine |
| Other names |
N-(3-Morpholinopropyl)-1-naphthylamine 4-(3-(1-Naphthylamino)propyl)morpholine |
| Pronunciation | /ˈfɔːr θri ˈwʌn næfˌθɪl.əˌmiː.nəʊ ˈprəʊ.pɪl ˈmɔː.fəˌliːn/ |
| Identifiers | |
| CAS Number | 97963-62-1 |
| 3D model (JSmol) | `3D structure;JSmol;C17H20N2O` |
| Beilstein Reference | 3445992 |
| ChEBI | CHEBI:73008 |
| ChEMBL | CHEMBL1614470 |
| ChemSpider | 33255574 |
| DrugBank | DB08951 |
| ECHA InfoCard | 100.125.588 |
| EC Number | EC 629-039-4 |
| Gmelin Reference | Gmelln Reference: **Gm 897414** |
| KEGG | C17948 |
| MeSH | Dimepranol |
| PubChem CID | 10197889 |
| RTECS number | UB8750000 |
| UNII | UA0F41585M |
| UN number | UN 2811 |
| CompTox Dashboard (EPA) | DTXSID5044376 |
| Properties | |
| Chemical formula | C17H22N2O |
| Molar mass | 299.41 g/mol |
| Appearance | Light yellow to yellow solid |
| Odor | Odorless |
| Density | 1.13 g/cm³ |
| Solubility in water | slightly soluble |
| log P | 2.98 |
| Acidity (pKa) | pKa = 9.24 |
| Basicity (pKb) | 5.87 |
| Magnetic susceptibility (χ) | -73.94 × 10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.653 |
| Dipole moment | 4.07 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 399.06 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -34.98 kJ/mol |
| Pharmacology | |
| ATC code | N06AX13 |
| Hazards | |
| Main hazards | Harmful if swallowed. Causes serious eye irritation. Causes skin irritation. May cause respiratory irritation. |
| GHS labelling | GHS05, GHS07 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P261, P264, P271, P272, P280, P302+P352, P321, P332+P313, P362+P364, P501 |
| Flash point | > 140°C |
| Lethal dose or concentration | LD50 oral rat 500mg/kg |
| LD50 (median dose) | LD50 (median dose): 230mg/kg (rat, oral) |
| NIOSH | NA |
| PEL (Permissible) | PEL (Permissible Exposure Limit) for 4-[3-(1-Naphthylamino)Propyl]Morpholine: **Not established** |
| REL (Recommended) | 10 mg |
| Related compounds | |
| Related compounds |
4-(3-Phenylpropyl)morpholine 4-(3-(Naphthalen-2-ylamino)propyl)morpholine 4-(3-(1-Naphthylamino)propyl)piperidine 4-(3-(1-Naphthylamino)propyl)pyrrolidine |
