Product Name: (3R)-3-Methylpiperazin-2-One
Chemical Formula: C5H10N2O
Chemical Family: Piperazinone Derivatives
Synonyms: 3R-Methyl-2-piperazinone
CAS Number: 124213-92-3
Recommended Uses: Intermediate for synthesis in the pharmaceutical and chemical industries
Manufacturer Information: Provided by the supplier; contact details required for specific batch
Emergency Contact Number: Refer to local poison control or emergency service
UN Number: Assigned as per regulatory requirements if classified as a dangerous good
GHS Classification: Eye Irritant, Skin Sensitizer, Harmful if swallowed
Signal Word: Warning
Hazard Statements: Causes mild to moderate eye and skin irritation, may induce respiratory discomfort, ingestion can lead to nausea and abdominal pain
Pictograms: Exclamation mark (irritant)
Routes of Exposure: Skin contact, eye contact, inhalation, ingestion
Precautionary Statements: Avoid direct contact with skin and eyes, ensure adequate ventilation, wash thoroughly after handling
Potential Health Effects: Temporary irritation, allergic reactions in sensitive individuals, symptoms include redness, itching, coughing
Chemical Identity: (3R)-3-Methylpiperazin-2-One
Purity: ≥ 95%
Impurities: By-products from synthesis, typically below 5%, non-hazardous at standard quantities
Other Components: No additives, stabilizers, or coloring agents reported in pure material
Concentration: 100% unless stated otherwise on batch-specific analysis
Skin Contact: Wash with plenty of water and soap, remove contaminated clothing, seek medical advice if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do; seek medical attention if irritation continues
Inhalation: Move to fresh air immediately, keep at rest, seek medical help if symptoms like dizziness or shortness of breath persist
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical attention if feeling unwell
Notes for Physicians: Treat symptomatically, no known antidote, monitor respiratory and gastrointestinal symptoms
Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, or alcohol-resistant foam
Special Hazards: Combustion produces carbon oxides, nitrogen oxides, toxic smoke
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective clothing
Specific Methods: Cool containers with water, avoid breathing vapors, evacuate area if necessary
Unusual Fire Hazards: Fumes can cause respiratory irritation in confined or poorly ventilated spaces
Personal Precautions: Wear chemical-resistant gloves, eye protection, long-sleeved clothing, avoid breathing dust or vapors
Environmental Precautions: Prevent product from entering drains, surface, or groundwater
Methods for Cleaning Up: Absorb spillage with inert material (sand, earth), collect in labelled containers, ventilate area thoroughly
Decontamination: Wash area with water after removal of bulk material, avoid use of strong acids or oxidizers
Disposal: As per local regulations for hazardous chemical waste
Handling: Use with adequate ventilation, avoid generation of dust, handle in accordance with good chemical hygiene practices, do not eat, drink, or smoke in handling areas
Storage Conditions: Store in tightly closed containers, away from direct sunlight, extremes of temperature, acids, and oxidizing agents
Storage Temperature: Recommended between 2-8°C; keep away from moisture
Incompatible Materials: Strong oxidizers, acids, alkalis
Packaging Requirements: Use non-reactive container materials (e.g., polyethylene, glass) with clear labeling
Engineering Controls: Local exhaust ventilation, eyewash stations, safety showers in proximity
Control Parameters: No established OSHA or ACGIH limits, minimize occupational exposure by practical means
Respiratory Protection: Approved respirators for nuisance dust or organic vapor if ventilation is inadequate
Hand Protection: Nitrile or butyl rubber gloves recommended
Eye Protection: Safety goggles with side shields
Skin Protection: Lab coats, aprons, closed footwear
Hygiene Measures: Regular handwashing, removal of contaminated clothing, do not wear contaminated garments outside of work area
Appearance: White to off-white solid, crystalline powder
Odor: Mild, amine-like
pH: Not available (solid form)
Melting Point: 80-84°C (batch-dependent)
Boiling Point: Decomposes before boiling at atmospheric pressure
Flash Point: Not easily flammable below 100°C as per current data
Solubility: Moderately soluble in water, soluble in most polar organic solvents
Partition Coefficient (log Kow): Not determined
Vapor Pressure: Low at room temperature
Evaporation Rate: Not rapid under ambient conditions
Density: Approximately 1.1 g/cm³
Decomposition Temperature: Above 150°C, releases ammonia and nitrogen oxides
Other Properties: Non-explosive, not oxidizing
Chemical Stability: Stable under recommended storage temperatures and inert conditions
Reactivity: Reacts with strong oxidizers, acids (possible heat release, hazardous vapors)
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, possible ammonia fumes
Polymerization: Not expected under normal conditions
Conditions to Avoid: Excessive heat, open flames, direct sunlight, strong acids and bases
Acute Toxicity: Oral LD50 (rat): >500 mg/kg (estimated range), low to moderate oral toxicity
Skin Corrosion/Irritation: May cause slight redness, itching, especially on prolonged or repeated contact
Serious Eye Damage/Irritation: Temporary pain or redness, full recovery expected with proper irrigation
Respiratory or Skin Sensitization: May trigger reactions in susceptible individuals
Chronic Effects: No evidence of mutagenicity, carcinogenicity, or reproductive toxicity in available literature
Other Risks: Large doses or prolonged exposure may cause headache, dizziness, mild gastrointestinal symptoms
Ecotoxicity: Not acutely toxic to aquatic organisms at typical discharge concentrations
Persistence and Degradability: Readily biodegradable in standard environmental conditions
Bioaccumulative Potential: Low, due to moderate water solubility and molecular size
Mobility in Soil: Moderate, expected to migrate with groundwater, avoid uncontrolled discharge
Other Effects: Avoid release to aquatic systems, report accidental large spills as per environmental regulations
Disposal Methods: Dispose as hazardous chemical waste, use licensed chemical disposal contractor
Containers: Triple-rinse containers or drums prior to recycling where permitted, otherwise treat as chemical waste
Precautions for Disposal: Follow local, national, and international guidelines, do not discharge into drains, waterways, or soil
Recommended Waste Code: Assigned based on use and specific local regulations
UN Number: Not classified as dangerous for transport in most jurisdictions, check shipping documentation
Transport Hazard Class: Not regulated under standard ADR, DOT, IMDG, or IATA classes
Packing Group: Not assigned
Proper Shipping Name: Chemical Not Otherwise Specified or Product Name per customs paperwork
Label Requirements: Standard chemical label indicating hazard classification, precautionary measures
Special Precautions: Protect from weather, do not transport with foodstuffs or oxidizers
International Regulations: Not listed under the Rotterdam, Stockholm, or Montreal protocols
US Regulations: Not listed as a controlled substance or known carcinogen, subject to TSCA inventory reporting
EU Regulations: Registered under REACH where required
Other jurisdictions: Observe workplace and environmental chemical safety acts
Labelling/Classification: In accordance with GHS and local chemical hazard communication standards
Restrictions: Professional use only, not for consumer applications
