Product Name: 3-(Piperazin-1-Yl)-1,2-Benzothiazole
Chemical Formula: C11H13N3S
Synonyms: 1-(1,2-Benzothiazol-3-yl)piperazine
Recommended Use: Research chemical, intermediate for pharmaceuticals
Manufacturer: Supplier contact details needed for emergencies
Emergency Phone Number: National poison hotline or supplier emergency contact info
Hazard Classification: Irritant to skin and eyes, may cause sensitization, respiratory tract irritation possible
Label Elements: Irritant pictogram, exclamation mark, hazard statements include 'Causes skin and eye irritation', 'May cause respiratory irritation'
Signal Word: Warning
Potential Health Effects: May cause nausea, headache if inhaled, possible allergic response on skin contact, risk to eyes on accidental exposure
Environmental Risk: Avoid release into the environment, aquatic toxicity not fully evaluated but not expected to bioaccumulate
Chemical Name: 3-(Piperazin-1-Yl)-1,2-Benzothiazole
CAS Number: 86434-46-4
Concentration: 100% pure unless noted on label
Impurities: Minor synthetic by-products below 0.1% not considered hazardous
Additives: None reported
Eye Contact: Rinse with plenty of clean water for 15 minutes, keep eye open, seek medical attention if irritation persists
Skin Contact: Remove contaminated clothing, wash affected area with mild soap and water, consult health professional for persistent redness or rash
Inhalation: Move to fresh air, monitor for breathing difficulty, provide oxygen if available and seek medical help if symptoms develop
Ingestion: Rinse mouth, do not induce vomiting, observe for symptoms and contact a poison control center or physician quickly
Notes to Physician: Treat symptomatically, monitor vital signs, consider supportive measures in case of severe exposure
Suitable Fire Extinguishing Media: Dry chemical, carbon dioxide, foam; avoid water jets
Specific Hazards: May emit nitrogen oxides, sulfur oxides, carbon monoxide and other toxic fumes if burned
Fire-Fighter Protection: Use self-contained breathing apparatus and protective clothing, avoid inhaling fumes
Explosion Risk: Not classified as explosive or flammable in solid form, dust may present minimum explosive risk if finely dispersed in air
Personal Precautions: Wear gloves, safety goggles, and protective clothing, ventilate area, avoid breathing dust
Spill Response: Sweep up material cautiously to avoid dust, use inert absorbents if needed, place in sealed container for disposal
Environmental Precautions: Prevent material from entering drains or watercourses, contain spill with barriers
Cleanup Methods: Clean surface thoroughly with water and mild detergent after collection, dispose of used cleaning materials safely
Safe Handling Guidance: Work in chemical fume hood or well-ventilated area, avoid creating dust, wear appropriate PPE during weighing and transfer
Storage Recommendations: Keep container tightly closed and stored at room temperature, away from incompatible substances such as strong acids, bases, or oxidizers
Incompatibilities: Avoid storage near heat sources or direct sunlight, do not mix with oxidizing materials
Specific Storage Precautions: Use original container, label clearly, monitor storage area for signs of leaks or deterioration
Engineering Controls: Use local exhaust ventilation, work in laboratory hood if handling bulk quantities or during dusty procedures
Occupational Exposure Limits: No established OSHA, ACGIH or other regulatory limits, best to use general dust and chemical exposure guidelines
Personal Protective Equipment: Laboratory coat, nitrile gloves, chemical safety glasses or goggles recommended, use N95 or equivalent mask for dust exposure
Hygiene Measures: Wash hands after handling, avoid eating or drinking in work areas, remove contaminated clothing and shoes before leaving area
Environmental Controls: Prevent accidental release into air, water, or soil, confirm laboratory has compliant air filtration and waste disposal procedures
Appearance: Off-white to light yellow solid or powder
Odor: No characteristic odor detectable at low concentrations
Molecular Weight: 219.31 g/mol
Melting Point: 150–155 °C (literature values may vary by sample purity)
Boiling Point: Decomposes before boiling
Solubility: Low solubility in water, soluble in organic solvents like DMSO, ethanol
pH (in solution): Not determined
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): Not measured
Other Data: Stable under recommended handling and storage
Chemical Stability: Stable at room temperature and in sealed containers
Conditions to Avoid: Excessive heat, open flames, moisture, UV light
Incompatible Materials: Strong oxidizers, acids, bases may cause hazardous reactions
Hazardous Decomposition: Combustion can generate toxic gases including nitrogen oxides, sulfur oxides, carbon monoxide
Polymerization: Not expected under normal conditions
Acute Toxicity: Exact LD50 not established, expected to be low by oral or dermal routes based on related compounds
Chronic Exposure: No reports of long-term human exposure, low level animal studies suggest low risk at common laboratory levels
Skin/Eye Contact: Can irritate skin and eyes, wash thoroughly after exposure
Respiratory Effects: Irritation possible if inhaled, no long-term respiratory damage reported in animal studies
Allergenic/Sensitization: Risk not ruled out, minimize exposure especially in those with chemical sensitivities
Carcinogenicity/Mutagenicity: Not listed as carcinogen or mutagen by ACGIH, IARC, NTP, OSHA
Other Health Effects: Possible mild central nervous system effects at high exposures, nausea and dizziness not ruled out based on chemical class
Toxicity to Aquatic Organisms: Not acutely toxic by standard aquatic tests, minimize release to environment
Persistence/Degradability: Not expected to rapidly degrade, lacking full data, proper waste management recommended
Bioaccumulation Potential: No significant data, chemical not expected to bioaccumulate based on structure
Mobility in Soil: Low to moderate mobility in soil, precaution taken to isolate material from water sources
Other Environmental Effects: Material not classified as hazardous waste, but best practice involves avoiding environmental exposure
Waste Treatment Methods: Dispose of unused product by incineration in a licensed chemical incinerator
Container Disposal: Empty containers should be triple rinsed and disposed of according to local regulations
Environmental Precautions: Never pour into drains or natural watercourses, follow approved hazardous waste collection systems
Reuse Recommendations: Avoid reusing containers for food or drink, keep all related waste clearly labeled
UN Number: Chemical not assigned a UN Number for transport
Shipping Name: Not classified as hazardous under international transport regulations
Transportation Hazards: None identified—double-bag product, use sturdy box or drum, seal against moisture and dust during shipping
Packing Group: Not applicable
Transport Labeling: General chemical labeling, include contact information, do not ship with foodstuffs
Inventory Status: Not listed in US TSCA, REACH, EINECS under generic name; laboratory use only
OSHA Hazard Communication: Hazardous Chemical—subject to standard workplace hazard communication rules
WHMIS Status (Canada): Classified as toxic material (D2B – skin/eye irritant)
SARA Title III: Not subject to reporting under SARA; check facility-specific requirements
Other Regulations: Observe best safety practices for laboratory chemicals, consult local regulations for additional requirements, maintain proper documentation for storage and waste movements
