Chemical Name: 3-Methyl Thiophene-2-Carboxylic Acid
Synonyms: 2-Carboxy-3-methylthiophene
CAS Number: 7327-37-9
Molecular Formula: C6H6O2S
Molecular Weight: 142.18 g/mol
Recommended Use: Laboratory chemical, research, fine chemical synthesis
Supplier: Chemical distributor or manufacturer contact details as listed on packaging
Emergency Telephone: National Poison Control Center or local emergency numbers found on container label
Classification: Acute oral toxicity (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity – single exposure (Category 3)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation, may cause respiratory irritation
Pictograms: Exclamation Mark
Precautionary Statements: Avoid breathing dust/fume, wash hands thoroughly after handling, wear protective gloves/protective clothing/eye protection/face protection, eat/drink/smoke only after washing hands, use only outdoors or in well-ventilated area, rinse eyes cautiously if contact occurs, seek medical advice if feeling unwell
Routes of Exposure: Inhalation, ingestion, skin, eyes
Potential Health Effects: May cause headache, dizziness, irritation of respiratory tract, stomach discomfort, skin redness, eye redness or watering
Chemical Name: 3-Methyl Thiophene-2-Carboxylic Acid
Concentration: ≥99% purity, trace impurities may vary by batch
CAS Number: 7327-37-9
EC Number: 230-781-7
Impurities Contributing to Hazard: None expected at declared purity
Inhalation: Remove individual to fresh air, offer artificial respiration if breathing has stopped, seek medical attention if symptoms persist or develop
Skin Contact: Remove contaminated clothing, rinse affected skin with plenty of water and gentle soap for at least fifteen minutes, consult medical advice for persistent irritation
Eye Contact: Flush eyes with plenty of clean water for at least fifteen minutes while keeping eyelids open, remove any contact lenses, obtain medical attention if discomfort continues
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, seek medical advice immediately, show physician product label or safety sheet
Advice to Physician: Treat symptoms, no specific antidote known, ensure adequate ventilation and supportive therapy as needed
Suitable Extinguishing Media: Foam, dry chemical powder, carbon dioxide (CO2), water spray (do not use direct stream of water)
Hazards from Combustion Products: Combustion may release toxic gases including sulfur oxides, carbon monoxide, carbon dioxide, and particulate matter
Special Protective Equipment for Firefighters: Wear full protective gear and positive pressure self-contained breathing apparatus
Precautions: Remove containers from fire area if possible, use water spray to cool unopened containers, avoid inhaling smoke or vapor
Flammability: Not highly flammable but may burn at high temperature
Specific Hazards: May decompose to release irritating or toxic fumes under fire conditions
Personal Precautions: Evacuate unnecessary personnel, use personal protective equipment such as gloves, goggles, and respirator, maintain adequate ventilation
Environmental Precautions: Prevent entry into waterways, drains, or soil, notify authorities if significant spill threatens environment
Methods for Cleaning Up: Use non-sparking tools, collect spillage with absorbent material (sand, diatomaceous earth), clean contaminated surface thoroughly with water and detergent, dispose of waste following legal requirements
Sensitive Populations: Keep children, elderly, and those with respiratory conditions away from spill area
Handling: Use with local exhaust or general ventilation, avoid inhaling dust or vapor, avoid contact with skin, eyes, and clothing, do not eat, drink, or smoke during use, wash hands after handling
Storage: Store in tightly closed container, keep in cool, dry, well-ventilated area away from sources of ignition and incompatible materials, segregate from oxidizing agents and strong acids, label all containers clearly with product name and hazard information
Incompatibilities: Strong oxidizing agents, strong acids, bases, moisture
Storage Temperature: Store at ambient temperature, avoid extreme temperatures or freezing
Engineering Controls: Use only in chemical fume hood or with local exhaust, ensure eye wash station and emergency shower available
Occupational Exposure Limits: No workplace exposure limits assigned by OSHA, NIOSH, or ACGIH for this compound
Respiratory Protection: Use NIOSH-approved respirator if airborne concentrations exceed recommended exposure levels
Hand Protection: Wear protective gloves made of nitrile, neoprene, or latex
Eye Protection: Chemical safety goggles or face shield required
Skin Protection: Wear lab coat, apron, or protective clothing to minimize skin contact
Hygiene Measures: Remove contaminated clothing and equipment before entering eating or drinking areas, wash thoroughly after handling
Appearance: White to light yellow powder
Odor: Slight characteristic odor similar to thiophenes
Odor Threshold: Not established
pH: Not determined
Melting Point / Freezing Point: Approximately 175–179°C
Boiling Point: Decomposes before boiling
Flash Point: Not available
Evaporation Rate: Not applicable (solid at room temperature)
Flammability: Not considered highly flammable
Relative Density: Approximately 1.44 g/cm3
Solubility: Slightly soluble in water; soluble in ethanol, DMSO, DMF
Partition Coefficient (n-octanol/water): Not determined
Vapor Pressure: Not appreciable
Vapor Density: Not applicable
Decomposition Temperature: Above melting point, emits toxic fumes
Viscosity: Not relevant (solid at standard conditions)
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: No hazardous reactivity expected with proper use
Conditions to Avoid: Heat, open flame, strong acids, bases, direct sunlight, moisture
Incompatible Materials: Strong oxidizing agents, strong bases, strong acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, sulfur oxides, volatile organic compounds
Polymerization: Will not occur under normal conditions
Acute Toxicity: Expected oral LD50 (rat) in range of 300–2000 mg/kg based on related thiophene compounds
Skin Corrosion/Irritation: Causes irritation on contact
Serious Eye Damage/Irritation: Causes eye irritation and redness
Respiratory Sensitization: May cause throat irritation, cough, and breathing difficulty
Skin Sensitization: Not known to cause allergic reaction
Germ Cell Mutagenicity: No reliable data available
Carcinogenicity: Not classified as carcinogen by IARC, NTP, ACGIH, or OSHA
Reproductive Toxicity: Not evaluated for reproductive toxicity
Specific Target Organ Toxicity – Single Exposure: May affect central nervous system (headache, dizziness)
Specific Target Organ Toxicity – Repeated Exposure: Information unavailable
Other Information: Prolonged or repeated exposure may aggravate pre-existing skin, respiratory, or eye conditions
Toxicity to Aquatic Organisms: Not expected to be acutely toxic, but avoid release to the environment based on similar organic compounds
Persistence and Degradability: Data not available; parent compound may persist under some conditions
Bioaccumulative Potential: No data available
Mobility in Soil: Product expected to be moderately mobile, dependent on local conditions
Other Adverse Effects: Discharge to waters may result in adverse effects to aquatic organisms
Precautions for Environment: Prevent product and contaminated material from entering natural waterways, drains, or sewers
Waste Treatment Methods: Dispose of contents and container in accordance with local, regional, and national regulations for hazardous laboratory waste
Disposal of Packaging: Triple rinse empty containers, puncture or crush prior to disposal, send to licensed waste facility
Special Precautions for Incineration or Disposal: Handle in chemical waste incinerators equipped with afterburner and scrubber to avoid release of toxic gases
Contaminated Material Handling: Dispose of contaminated gloves, towels, and absorbents as hazardous chemical waste
UN Number: Not classified as hazardous for transport by most regulatory agencies
UN Proper Shipping Name: Not regulated
Transport Hazard Class(es): None assigned
Packing Group: Not assigned
Environmental Hazards: Avoid release into environment during transportation
Special Precautions for Transport: Keep containers tightly sealed, protected from physical damage, moisture, and incompatible chemicals, ensure clear labeling with contents and hazards
OSHA: Product not listed as hazardous under OSHA Hazard Communication Standard
TSCA: Listed or complies with TSCA inventory
SARA Title III: No components listed in SARA 302, 304, or 313 categories
California Proposition 65: Not on Proposition 65 list as of last review
REACH: Substance registration or exemption may apply in European regions
Other Regulatory Status: Follow regulations in country of use, including workplace safety, waste, environmental, and transport regulations as applicable
