Product Name: 3-Methyl-1,2-Benzothiazole-1,1-Dione
Synonyms: 3-Methylisothiazole-1,1-dione
CAS Number: 615-21-2
Recommended Use: Laboratory research, chemical synthesis, specialty manufacturing
Supplier Name: Provide full business address, technical contact number, email, and emergency contact details
Manufacturing Location: Plant, research facility, or supplier warehouse addresses
Emergency Overview: Contains a strong odor, may cause eye, skin or respiratory irritation, not intended for general consumer use
Globally Harmonized System Classification: Acute toxicity (Oral Category 4), Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity—single exposure (Category 3, respiratory tract)
Signal Word: Warning
Hazard Statements: Harmful if swallowed or inhaled. Causes skin and eye irritation. May cause respiratory irritation.
Pictograms: Exclamation mark
Precautionary Statements: Do not inhale dust, avoid contact with eyes, skin, and clothing, wash hands thoroughly after handling, use only outdoors or in well-ventilated area, wear protective equipment; store locked up, and dispose of contents according to local regulations
Route of Exposure: Skin, eyes, ingestion, inhalation
Symptoms: Burning, redness, swelling, coughing, sore throat, stomach pain, headaches, nausea
Chemical Identity: 3-Methyl-1,2-Benzothiazole-1,1-Dione
CAS Number: 615-21-2
Molecular Formula: C8H5NO2S
Molecular Weight: 179.19 g/mol
Component: 3-Methyl-1,2-Benzothiazole-1,1-Dione (100%)
Impurities: None expected under typical manufacturing controls; trace contaminants possible, not at hazardous levels
Inhalation: Remove person to fresh air. If breathing is labored, provide oxygen or artificial respiration as needed. Seek medical attention for continued irritation or distress.
Skin Contact: Rinse skin immediately with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes, launder before reuse. Seek medical help for persistent irritation.
Eye Contact: Immediately flush eyes with water for 10-20 minutes, holding eyelids apart. Remove contact lenses if easy to do. Seek immediate medical attention.
Ingestion: Rinse mouth thoroughly. Do not induce vomiting. Never give anything by mouth to an unconscious person. Get prompt medical attention.
Most Important Symptoms: Irritation, nausea, headache, difficulty breathing
Notes for Physician: Treat symptomatically. Monitor for respiratory, dermal, or gastrointestinal effects.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide (CO2), or alcohol-resistant foam
Unsuitable Agents: Direct water jet can spread chemical
Hazards from Burning: Toxic gases such as nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide
Protective Equipment: Self-contained breathing apparatus (SCBA), flame and chemical resistant clothing
Specific Methods: Move containers from fire area if safe, cool exposed containers with water; avoid run-off into drains
Hazardous Combustion Products: May release irritant or toxic fumes under fire conditions; do not breathe vapor or smoke
Personal Protection: Wear gloves, goggles, protective clothing, use respirator if ventilation is inadequate
Spill Response: Ventilate area. Remove ignition sources. Prevent further leakage or spillage if safe to do so. Dike and absorb with inert material such as dry sand or noncombustible absorbent.
Clean-Up Procedures: Shovel or sweep up and place in a suitable labeled container. Wash spill area with water and detergent after material pick up is complete.
Environmental Precautions: Prevent entry into drains, surface or ground water, soil, and sewers.
Precautions for Safe Handling: Avoid dust generation and contact with skin, eyes, or clothing. Use only with adequate ventilation; do not eat, drink, or smoke near this compound.
Storage Conditions: Store in tightly closed, clearly labeled containers in a cool, dry, well-ventilated place away from incompatible materials including oxidizing agents, strong acids, and bases.
Other Recommendations: Keep away from heat, spark, and open flame. Limit access to authorized personnel.
Storage Temperature: Typically, store between 2–8°C; check supplier’s product stability conditions.
Engineering Controls: Use fume hood or enclosure if dust or vapor is expected. Provide emergency eyewash and safety showers in work area.
Occupational Exposure Limits: No established OSHA PEL or ACGIH TLV for this specific compound, but minimize exposure.
Respiratory Protection: Use NIOSH-approved respirator in the event of insufficient ventilation. Prefer dust or vapor filter depending on process.
Skin Protection: Wear chemical-resistant gloves (nitrile, neoprene), long sleeved lab coat or apron.
Eye Protection: Safety goggles with side shields or full face shield
Hygiene Measures: Wash hands before breaks, after handling, and after use of restroom. Remove contaminated clothing, wash before reuse.
Physical State: Solid (may be crystalline or powder form)
Color: Light yellow or off-white
Odor: Pungent or sulfurous
Melting Point: 108–112°C (depending on purity and crystalline form)
Boiling Point: Decomposes before boiling
Flash Point: Not readily available; treat as combustible
Solubility: Slightly soluble in water; more soluble in organic solvents like ethanol, acetone
Vapor Pressure: Data not available
Density: Approximately 1.35 g/cm3
pH: Not applicable; not water soluble enough
Partition Coefficient (log Kow): Data limited—moderate potential for bioaccumulation
Evaporation Rate: Not determined
Auto-ignition Temperature: Not established
Decomposition Temperature: Above melting; may emit toxic fumes
Chemical Stability: Stable under recommended use, handling, and storage conditions.
Reactivity: Not highly reactive under ordinary conditions.
Conditions to Avoid: Heat, flames, sparks, static discharge, moisture.
Materials to Avoid: Strong oxidizing agents, strong acids, bases, agents that enhance decomposition
Hazardous Decomposition Products: Nitrogen oxides (NOx), sulfur oxides (SOx), carbon dioxide, carbon monoxide, other unidentified toxic fumes if burned
Polymerization: No hazardous polymerization expected during standard use
Routes of Entry: Skin, inhalation, ingestion, eye contact
Acute Toxicity: May cause skin and respiratory irritation. Harmful if swallowed (oral LD50 for rats believed 50–500 mg/kg, but detailed animal data is limited).
Chronic Effects: Prolonged or repeated exposure can produce dermatitis, respiratory irritation, sensitization in susceptible individuals.
Symptoms: Headache, nausea, vomiting, burning sensation, cough, shortness of breath, allergic reactions on skin; more severe cases may involve central nervous system depression
Carcinogenicity: No conclusive evidence; not listed by IARC, NTP, or OSHA as a known carcinogen
Mutagenicity: Insufficient data available
Reproductive Toxicity: Data lacking, avoid unnecessary exposure
Ecotoxicity: Limited data on aquatic and terrestrial toxicity; may present moderate hazard to aquatic organisms if released in large quantities.
Persistence and Degradability: Does not quickly degrade in soil or water; may persist under some environmental conditions.
Bioaccumulation Potential: Moderate, due to lipophilicity.
Mobility in Soil: Moderate, based on solubility and partition coefficient.
Known Environmental Impacts: Prevent uncontrolled release; avoid contamination of surface and groundwater.
Other Adverse Effects: Not expected to cause ozone depletion or other specific environmental hazards based on structure
Waste Treatment Methods: Dispose in accordance with local, state, and federal regulations. Incineration preferred for small laboratory quantities under supervision of licensed professionals.
Container Handling: Empty containers may retain residue; treat as hazardous. Do not reuse or cut containers.
Disposal of Spill Cleanup Solutions: Collect absorbent, sweepings, and contaminated material into approved waste containers for proper disposal.
Recommended Disposal Route: Use approved chemical waste service or facility. Do not pour into drain or natural waterways.
UN Number: Not assigned for this material unless classified as regulated
UN Proper Shipping Name: Not regulated for ground or air unless transported in bulk or mixed collection
Transport Hazard Class: Not classified under most transport regulations, but treat as hazardous
Packing Group: Not assigned unless bulk or hazardous by mixture
Marine Pollutant: None identified, though take care to prevent spills to water
Special Transport Precautions: Use sealed packaging. Keep away from sparks, flame, and incompatible chemicals during transport. Notify carrier of any hazardous potential if shipped in non-original containers.
Regulatory Labels: Attach hazard labels according to chemical package regulations if volumes exceed research use thresholds.
TSCA (US Toxic Substances Control Act): Listed or expected to be in TSCA inventory
EINECS (Europe): On inventory or notified under REACH regulations
OSHA: Treat as hazardous chemical under Hazard Communication Standard
SARA Title III Sections 311/312: Acute health hazard; chronic health hazard not established
California Proposition 65: Not listed as a known carcinogen or reproductive toxin
Canadian DSL/NDSL: Confirmed listed, subject to workplace labeling and controls
REACH Compliance: Producer or importer responsible for any substances handled above 1 metric ton in Europe
Other Local/National Listings: Consult applicable state or country chemical inventory and labeling requirements; conform to GHS hazard communication and waste management policy
