Product Name: (S)-1-Tert-Butyloxycarbonyl-3-Hydroxypiperidine
Chemical Formula: C10H19NO3
Chemical Family: Boc-protected piperidine derivatives
CAS Number: 119879-67-7
Synonyms: (S)-Boc-3-Hydroxypiperidine
Manufacturer: Supplier contact details as listed on invoice or order
Recommended Uses: Laboratory reagent, pharmaceutical intermediate
Emergency Telephone: Listed on manufacturer's official documentation
GHS Classification: Irritant to eyes and skin, mild respiratory irritant, otherwise displays low acute toxicity by oral or dermal routes
Signal Word: Warning
Hazard Statements: Causes mild to moderate eye irritation, prolonged contact may dry or crack the skin, inhalation could cause minor respiratory discomfort
Pictograms: Exclamation mark for irritant
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, use only with adequate ventilation, avoid contact with skin and eyes
Chemical Name: (S)-1-Tert-Butyloxycarbonyl-3-Hydroxypiperidine
Concentration: 98% and above (main component)
Impurities: Trace organic contaminants (<2%), mainly from synthesis or storage
Stabilizing Additives: None commonly present
Inhalation: Move exposed person to fresh air, seek medical attention if symptoms persist
Skin Contact: Wash affected area thoroughly with soap and plenty of water, remove contaminated clothing, seek medical advice if irritation continues
Eye Contact: Rinse eyes under running water for several minutes, keep eyelids open and remove contact lenses if possible, consult a physician for persistent redness or discomfort
Ingestion: Rinse mouth with water, never give anything by mouth to an unconscious person, seek immediate medical advice, monitor for nausea or gastrointestinal distress
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam
Special Hazards: Product can emit toxic fumes of nitrogen oxides and carbon oxides during combustion
Precautions for Firefighters: Wear self-contained breathing apparatus, full protective gear, avoid inhaling fumes
Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides, traces of other organic compounds
Advice: Remove product containers from fire area if possible and safe, cool nearby containers with water spray to prevent heat exposure and pressure buildup
Spill Response: Avoid breathing dust, ventilate area, prevent further release, contain spill with inert absorbent material (e.g., sand or vermiculite)
Personal Protection: Wear chemical-resistant gloves, safety goggles, laboratory coat, respirator if dust generated
Cleanup Methods: Sweep up and collect in suitable waste container, wash spill area with water and mild detergent, avoid runoff to drains or surface water
Environmental Precautions: Prevent large quantities from entering waterways, sewers or soil
Safe Handling: Handle in a chemical fume hood, avoid skin and eye contact, minimize dust generation, keep away from foods and drinks
Storage Requirements: Store in tightly closed original containers, keep in a cool, dry place, protect from light and incompatible materials (acids, strong oxidizers)
Temperature Sensitivity: Stable under recommended storage, do not freeze, avoid prolonged exposure to elevated temperatures
Incompatible Materials: Strong acids, bases, oxidizers, moisture, sources of ignition
Packaging Materials: Use glass, plastic, or lined metal containers
Engineering Controls: Operate with adequate exhaust ventilation, use chemical fume hood for large quantities or dust-generating procedures
Protective Equipment: Safety glasses, gloves made from nitrile or neoprene, laboratory coat, dust mask or respirator if necessary
Exposure Limits: No regulatory limits established, minimize exposure as good laboratory practice
Hygiene: Wash thoroughly after handling, remove and clean protective equipment before eating or drinking, avoid touching face during work
Appearance: White to off-white crystalline solid
Odor: Faint organic odor, not pungent
Melting Point: 72–76°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in organic solvents (e.g., methanol, DCM, ethanol), weak solubility in water
Vapor Pressure: Not volatile at room temperature
Density: 1.07–1.13 g/cm³
pH (aqueous): Not applicable
Other Data: Stable in air, can hydrolyze slowly in presence of acids or bases, decomposes on heating
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity Hazards: Product reacts with acids and strong oxidizers; slow hydrolysis in presence of moisture
Hazardous Polymerization: Not reported
Decomposition Products: Thermal decomposition can produce toxic nitrogen and carbon oxides
Conditions to Avoid: Heat, flames, moisture, incompatible chemicals
Acute Toxicity: Low oral and dermal toxicity based on similar compounds
Skin Irritation: Contact can cause mild or transient redness, dryness, possible cracking on repeated contact
Eye Irritation: Possible redness, watering, transient discomfort
Sensitization: No significant sensitization reaction reported
Chronic Exposure: Not known to cause long-term health effects, but unnecessary exposure should be avoided
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity/Genotoxicity: Not identified as mutagenic, data limited
Ecotoxicity: Product not expected to show significant toxicity to aquatic life, but avoid large releases
Persistence and Degradability: Slowly biodegradable, will degrade over time in soil and water
Bioaccumulation Potential: Expected to show low bioaccumulation based on structure
Mobility in Soil: Moderate mobility, dependent on site conditions
Other Hazards: At high concentrations could cause localized harm to aquatic organisms, fish or plants
Disposal Methods: Dispose according to local, regional, and national regulations, preferably through licensed chemical waste contractor
Contaminated Packaging: Triple-rinse and offer for recycling or reconditioning if possible, otherwise discard with hazardous waste
Precautions: Do not pour into drains or natural environment, keep residues secure until proper disposal
Waste Codes: Per regulations on organic laboratory chemicals and pharmaceutical intermediates
UN Number: Not classified as a dangerous good for transport by land (ADR), sea (IMDG), or air (IATA)
Transport Hazard Class: Not regulated
Labeling: No specific transport labeling needed under current guidelines, but clearly identify with product information
Packing Group: Not assigned
Special Precautions: Use standard packaging to prevent spillage, secure all containers, keep away from incompatible materials during transport
Inventory Listings: Check local chemical inventories (REACH, TSCA, DSL, ENCS, AICS)
TSCA: Not listed for specific regulation
European Union: Not subject to specific hazard classification or labeling in current ECHA databases
Other Regulations: Use subject to general workplace and laboratory safety regulations, always follow best practices for chemical hygiene
Restrictions: No special restrictions beyond standard lab and storage protocols, monitor updates for occupational exposure limits
Right to Know: Communicate hazard information as per local guidelines, include safety training for handlers.
