Material Safety Data Sheet: 3-Hydroxy-1-Methyl-2,5-Pyrrolidinedione

Identification

Product Name: 3-Hydroxy-1-Methyl-2,5-Pyrrolidinedione
Synonyms: N-Methyl-3-hydroxyglutarimide, Methylhydroxyglutarimide
Chemical Formula: C5H7NO3
Molecular Weight: 129.11 g/mol
CAS Number: 1003-29-8
Manufacturer: [Company name], [Address], [Contact number], [Emergency number]

Hazard Identification

Classification: Irritant to eyes and skin, possible respiratory tract irritant
GHS Label Elements: Warning pictogram, Signal word: WARNING
Hazard Statements: Causes serious eye irritation, may cause skin irritation, inhalation may cause respiratory irritation, may be harmful if swallowed
Precautionary Statements: Use protective gloves, avoid breathing dust or fumes, wash thoroughly after handling, use only outdoors or in well ventilated areas

Composition / Information on Ingredients

Chemical Identity: 3-Hydroxy-1-Methyl-2,5-Pyrrolidinedione
Concentration: ≥99%
Impurities: Trace amounts of related impurities or manufacturing byproducts
Additives: None known

First Aid Measures

Inhalation: Move to fresh air, give oxygen if breathing is difficult, seek medical attention if symptoms persist.
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, seek medical advice for irritation.
Eye Contact: Flush eyes immediately with plenty of water for several minutes, remove contact lenses if present, continue rinsing, seek medical attention.
Ingestion: Rinse mouth, seek medical attention, do not induce vomiting unless instructed by a healthcare provider.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Media: High-velocity water jets
Hazards from Combustion: Carbon oxides, nitrogen oxides, possible toxic fumes
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Special Procedures: Use water spray to cool containers, avoid inhaling combustion fumes, evacuate area if needed

Accidental Release Measures

Personal Precautions: Wear protective gloves, goggles, and suitable clothing, avoid breathing dust
Environmental Precautions: Prevent entry to waterways or soil, use physical barriers
Spill Cleanup Methods: Vacuum or sweep up material, avoid creating dust, place in appropriate container for disposal, provide ventilation during clean-up

Handling and Storage

Handling: Handle in a chemical fume hood or well ventilated area, minimize dust generation, avoid direct contact, wash hands after use
Storage: Store in tightly closed containers, away from incompatible materials (strong oxidizers, acids, bases), keep in a cool, dry, ventilated space, protect from moisture, segregate from food and beverages

Exposure Controls and Personal Protection

Exposure Limits: Not established for this compound, general dust limits may apply
Engineering Controls: Use local exhaust or general ventilation to reduce exposure
Personal Protective Equipment: Chemical-resistant gloves, splash goggles, lab coat or apron, suitable dust mask or respirator
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing, avoid eating or drinking in the work area

Physical and Chemical Properties

Form: Crystalline powder
Color: White to off-white
Odor: Odorless or faint odor
Melting Point: 138-142°C
Boiling Point: Not determined
Solubility: Soluble in water, slightly soluble in alcohol
Vapor Pressure: Not available
Density: Approximately 1.39 g/cm³
pH: Slightly acidic in solution
Flash Point: Not applicable
Evaporation Rate: Not available

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Not reactive under normal conditions
Conditions to Avoid: Excess heat, direct sunlight, moisture
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, under fire conditions toxic fumes may develop

Toxicological Information

Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Effects: Causes irritation to skin, eyes, and respiratory tract, ingestion can cause gastrointestinal discomfort
Chronic Effects: Long-term exposure tests are lacking, avoid repeated or prolonged contact
LD50 (oral, rat): Data not available
Symptoms: Redness, burning, possible nausea if ingested

Ecological Information

Aquatic Toxicity: Toxicity data not well studied, precaution advised around water systems
Persistence and Degradability: Expected to degrade slowly in environment
Bioaccumulative Potential: Low based on molecular structure, further data lacking
Mobility in Soil: Likely moderate due to water solubility, risk of leaching through soil
Other Adverse Effects: Large releases may impact aquatic organisms

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, state, and federal regulations
Contaminated Packaging: Rinse containers, dispose as chemical waste
Environmental Precautions: Do not discharge into drains, surface or groundwater
Recommended Disposal: Incinerate at approved facilities, do not recycle

Transport Information

UN Number: Not regulated
Transport Hazard Class: Not assigned
Packing Group: Not applicable
Proper Shipping Name: Not regulated under current transport rules
Special Precautions: Avoid breakage, prevent dust release, protect from impacts and moisture during transit

Regulatory Information

US TSCA: Listed or regulated
EU REACH: Substance not registered, limited data available
OSHA: Treated as hazardous chemical, general industry regulations apply
SARA Title III: Not listed
California Prop 65: Not listed
Other Regulations: Local and national chemical inventory status should be checked, always follow laboratory or workplace chemical safety protocols