Chemical Name: 3-Aminopyrrolidine
Synonyms: 3-Amino-1-pyrrolidine, Pyrrolidin-3-amine
CAS Number: 15164-47-9
Molecular Formula: C4H10N2
Molecular Weight: 86.14 g/mol
Recommended Use: Laboratory chemicals, research and development
Supplier Details: Chemical supplier contact info, emergency phone number
Date Prepared: [Insert Date]
GHS Classification: Acute toxicity (oral, dermal, inhalation), skin irritation, eye irritation
Hazard Symbols: GHS07 (Exclamation mark for irritant)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid inhalation, avoid contact with skin and eyes, wash hands thoroughly after handling, wear protective gloves and goggles
Emergency Overview: Colorless to pale yellow liquid or crystalline solid, pungent odor, harmful effects possible on ingestion and dermal contact
Substance: 3-Aminopyrrolidine
Chemical Identity: 3-Aminopyrrolidine
CAS Number: 15164-47-9
Concentration: >98% (for most laboratory formulations)
Impurities: Trace organic solvents and water (may occur depending on transport and storage conditions, generally less than 2%)
General Guidance: Remove source of exposure; check vital signs; give medical attention immediately
If Inhaled: Move person to fresh air, monitor for respiratory distress, provide oxygen if needed, get medical help
If on Skin: Take off contaminated clothing, wash skin with plenty of water and soap, seek medical aid for any irritation
If in Eyes: Rinse cautiously with water for at least 15 minutes, keep eyelids open, avoid rubbing, get medical attention promptly
If Swallowed: Rinse mouth with water, seek immediate medical care, do not give anything by mouth to an unconscious person
Symptoms of Exposure: Redness, irritation, burning sensation, coughing, difficulty breathing, nausea
Suitable Extinguishing Media: Water spray, dry chemical powder, carbon dioxide, foam
Unsuitable Extinguishing Media: Direct water jet
Specific Hazards during Fire: Combustible, produces irritating and toxic fumes (nitrogen oxides, carbon monoxide, carbon dioxide) on combustion
Fire-fighter Protection: Wear self-contained breathing apparatus and chemical protective clothing
Advice for Firefighters: Cool containers with water spray from a safe distance, avoid inhalation of combustion products
Personal Precautions: Ventilate area, evacuate unnecessary personnel, avoid dust or vapor generation
Protective Equipment: Chemical-resistant gloves, safety goggles, protective clothing, use appropriate mask/respirator
Environmental Precautions: Prevent further leakage, spillage, or entry into drains, surface water, or soil
Clean-up Methods: Absorb liquid or collect solid with inert absorbent (sand, earth, vermiculite), shovel into labeled container, dispose of according to local regulations
Handling: Work in a well-ventilated area, keep containers tightly closed when not in use, avoid breathing vapors or dust, do not eat, drink, or smoke during use
Storage Conditions: Store in a tightly closed container in a cool, dry, well-ventilated place away from incompatible materials (strong oxidizers, acids), keep from heat and ignition sources
Incompatibility: Strong oxidizing agents, acids, acid chlorides
Hygiene Measures: Wash hands, forearms, and face thoroughly after handling, remove contaminated clothing and wash before reuse
Control Parameters: No specific occupational exposure limits established for 3-Aminopyrrolidine
Engineering Controls: Use chemical fume hood for laboratory handling, local exhaust ventilation to reduce vapor or dust levels
Personal Protection: Nitrile or rubber gloves, safety goggles, chemical-resistant apron or lab coat, NIOSH-approved respirator (for high concentrations)
Environmental Controls: Prevent spillage and runoff, use containment methods if handling larger quantities
Appearance: Colorless to pale yellow liquid or crystals
Odor: Ammonia-like, pungent
pH: Alkaline (basic, typical amine pH range)
Melting Point: 13-16°C
Boiling Point: 172-175°C
Flash Point: Not widely reported; estimated >60°C
Evaporation Rate: Not determined
Flammability: Combustible
Vapor Pressure: Low at room temperature
Solubility: Miscible with water, soluble in ethanol and other polar solvents
Partition Coefficient (log Kow): Estimated negative, indicating hydrophilicity
Vapor Density: Heavier than air
Chemical Stability: Stable under normal laboratory conditions
Hazardous Reactions: May react with acids, acid chlorides, or oxidizers to produce harmful gases
Decomposition Products: Nitrogen oxides, carbon oxides, ammonia, irritating fumes
Conditions to Avoid: Excessive heat, exposure to air (long-term), moisture if not intended
Incompatibility: Acidic compounds, strong oxidizing agents, acid chlorides
Likely Routes of Exposure: Inhalation, ingestion, skin or eye contact
Acute Effects: Harmful if swallowed or inhaled, may cause burns or irritation to skin and eyes
Chronic Effects: Prolonged or repeated exposure may cause dermatitis and respiratory tract irritation
Toxicity Data: Oral LD50 (rat): Not widely published, estimated between 200-300 mg/kg
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Other Health Effects: May cause headaches, nausea, dizziness with inhalation; skin absorption possible
Ecotoxicity: Low predicted; specific aquatic toxicity data not available; should avoid uncontrolled release to water
Persistence and Degradability: Expected to degrade by hydrolysis and microbial action
Bioaccumulation: Low potential (hydrophilic, low log Kow)
Mobility in Soil: Likely to be mobile in soil and water due to water solubility
Other Adverse Effects: Spills or improper disposal could impact aquatic environments; treat as hazardous to aquatic life as a precaution
Disposal Methods: Incinerate at appropriate chemical waste facility in accordance with local, regional, and national regulations
Special Precautions: Do not allow chemical or containers to reach drains, water bodies, or open environment
Contaminated Packaging: Dispose of as hazardous waste, ensure packages are empty and rinsed if possible, affix appropriate hazard labeling
UN Number: Not classified as hazardous for transport under most international guidelines (consult latest regulations)
Transport Hazard Class: Not regulated, but best practice to handle as if hazardous; use suitable packaging
Packing Group: Not assigned
Proper Shipping Name: 3-Aminopyrrolidine, Chemical (not otherwise specified)
Special Precautions: Secure containers upright, prevent leakage or exposure during transit, keep away from incompatible substances
Regulatory Status: Not listed as a controlled substance
Inventory Listings: Appears in TSCA (US), REACH (EU), other local chemical inventories depending on jurisdiction
Labeling Requirements: Comply with local regulations for chemical hazards and workplace labeling
Other Regulations: Users must ensure compliance with workplace safety and chemical handling rules under OSHA, WHMIS, or equivalent standards
Safety Assessment Recommendations: Conduct risk assessment for each process, maintain records of use and exposures in workplace settings, provide safety training for staff using 3-Aminopyrrolidine
