Product Name: 3-Aminopyrazine-2-Carboxylic Acid
Chemical Formula: C5H5N3O2
CAS Number: 117824-04-3
Synonyms: Pyrazine-2-carboxylic acid, 3-amino-; 3-Amino-2-pyrazinecarboxylic acid
Recommended Use: Research chemical, synthesis intermediate
Manufacturer/Supplier: Chemical suppliers and research distributors
Contact Details: Emergency phone and address typically provided by manufacturer
Classification: Not classified as hazardous under GHS criteria for most jurisdictions, though dust or powder form may cause irritation to eyes, skin, and respiratory system
Signal Word: Warning
Hazard Statements: May cause minor respiratory irritation, skin or eye irritation upon contact
Pictograms: Exclamation mark (if dust exposure)
Precautionary Statements: Avoid breathing dust, wash skin thoroughly after handling, wear protective gloves and eye protection, avoid release to the environment
Potential Health Effects: Irritation of mucous membranes, eyes, or skin possible; asthmatic individuals may experience symptoms if inhaled
Chemical Name: 3-Aminopyrazine-2-Carboxylic Acid
Concentration: ≥98% (typical for laboratory grade)
Impurities: Trace levels of other pyrazine derivatives possible, exact content depends on lot
Other Components: No additives recognized in analytical grade samples
Inhalation: Move affected person to fresh air, monitor for respiratory distress, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, flush skin with soap and water for several minutes; medical advice for irritation
Eye Contact: Rinse cautiously with water for at least 15 minutes; remove contact lenses, seek ophthalmologist if irritation continues
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, seek immediate medical care in case of pain or persistent discomfort
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: Direct water jets may spread powder
Specific Hazards: May decompose at high temperature, emitting toxic fumes such as nitrogen oxides and carbon oxides
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective gear for chemical fires
Firefighting Instructions: Cool fire-exposed containers with water spray, avoid inhaling smoke, isolate area
Personal Precautions: Use respiratory protection, avoid dust formation, employ suitable gloves and chemical goggles
Environmental Precautions: Prevent entry into drains, waterways, soil
Methods for Cleaning Up: Sweep or vacuum up spilled material carefully without creating dust, transfer to suitable closed containers for disposal, ventilate area, wash spill site after material pick-up is complete
Handling: Wear personal protective equipment, avoid inhaling dust or vapors, prevent contact with eyes or skin, use only in well-ventilated areas, keep away from ignition sources
Storage: Store in tightly closed containers, in a cool, dry, silver-foil-protected place away from light, incompatible chemicals, moisture, and heat sources, use secondary containment for large quantities
Control Parameters: No occupational exposure limit values established
Engineering Controls: Work in fume hood or use local exhaust, maintain good general ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile or PVC), safety goggles, laboratory coat, respirator if ventilatory controls inadequate
Hygiene Measures: Wash hands after handling, remove contaminated clothing, do not eat, drink or smoke in work area, decontaminate equipment and work surfaces after use
Appearance: White to light beige crystalline powder
Odor: Slight chemical or none detectable
Odor Threshold: Not determined
pH: 2.0–2.6 (10 g/L, H2O, 20°C)
Melting Point: Approximately 209-211°C (varies by purity)
Boiling Point: Not easily measurable; decomposes before boiling
Solubility: Sparingly soluble in water, more soluble in methanol and DMSO
Vapor Pressure: Not available; presumed low
Density: About 1.5 g/cm3 (estimate)
Partition Coefficient (log Kow): Data not available
Flash Point: Not applicable
Autoignition Temperature: No data
Explosive Properties: Not classified as explosive
Oxidizing Properties: Not oxidizing under normal laboratory conditions
Chemical Stability: Stable under normal temperature and pressure, degrades with prolonged exposure to light, moisture, or extreme heat
Conditions to Avoid: Strong oxidizers, strong bases, excessive heat, direct sunlight, damp storage
Incompatible Materials: Strong oxidants, strong alkalis, reducing agents
Hazardous Decomposition Products: May emit toxic nitrogen oxides, carbon oxides if combusted or decomposed
Possibility of Hazardous Reactions: No violent reactivity with expected lab reagents but caution near incompatible chemicals
Acute Toxicity: Data limited or not available; analogs suggest low oral and dermal toxicity in rodents
Skin Corrosion/Irritation: May cause mild irritation upon prolonged contact
Serious Eye Damage/Irritation: May produce mild redness or watering
Respiratory Issues: Dust or powder may irritate upper respiratory tract
Germ Cell Mutagenicity, Carcinogenicity: No data available, not recognized as mutagenic or carcinogenic based on available structural analogy
Reproductive Toxicity: No findings available
Target Organ Effects: No organ-specific toxicity identified in literature
Chronic Effects: No long-term studies found for repeated exposure; prudent to minimize chronic exposure
Ecotoxicity: Data unavailable for aquatic or terrestrial environments; analog compounds show low acute toxicity
Persistence and Degradability: Not readily degradable; slow breakdown in soil and water suspected
Bioaccumulation: Low potential for bioaccumulation due to low log Kow, water solubility
Mobility in Soil: Expected to exhibit some mobility in aquatic environments owing to water solubility
Other Adverse Effects: No known ozone depletion or hazardous atmospheric effects
Waste Treatment Methods: Handle and discard as laboratory chemical waste; incineration in permitted facility recommended, follow local, regional, and national waste management regulations
Disposal of Containers: Rinse residue out with a compatible solvent, dispose of containers as hazardous waste
Contaminated Packaging: Empty containers or liners may retain traces, must be managed as hazardous material
UN Number: Not regulated as a dangerous good
Proper Shipping Name: Not classified under ADR, IMDG, IATA
Transport Hazard Classes: None assigned
Packing Group: Not applicable
Environmental Hazards: Not designated as hazardous for transport
Special Precautions: Keep tightly sealed during transport, protect from moisture, store upright
Safety, Health and Environmental Regulations/Legislation: Not listed as a controlled substance under TSCA, REACH, or other common chemical inventories; always check national registers before planning import or commercial use
Labelling Requirements: Laboratory chemicals label with hazard pictograms and warnings in accordance with local industrial hygiene standards
Chemical Safety Assessment: Not performed by producer in most cases due to scale of use; use risk management and common sense based on similar compounds
