Material Safety Data Sheet: 3-Aminohomopiperidine

Identification

Product Name: 3-Aminohomopiperidine
Chemical Formula: C6H14N2
CAS Number: [10500-76-0]
Recommended Use: Laboratory chemical, chemical manufacturing
Supplier Details: Manufacturer or distributor contact info; emergency phone provided
SDS Number: Assigned per batch; reference documentation or packaging

Hazard Identification

Classification: Harmful if swallowed or inhaled, serious eye damage, skin irritation possible
Signal Word: Warning
Hazard Statements: Harmful to mucous membranes, eyes, and skin, causes irritation, may trigger respiratory distress if inhaled in high concentrations, possibility of nervous system effects based on structure, can trigger allergic response in rare cases
Pictograms: Exclamation mark, health hazard symbol
Precautionary Statements: Avoid contact and inhalation, use adequate ventilation, wash hands thoroughly after handling, carry out activities in a fume hood

Composition / Information on Ingredients

Chemical Name: 3-Aminohomopiperidine
Common Names: Homopiperidin-3-amine
Synonyms: 3-Amino-azepane
Concentration: Typically supplied as pure substance, purity levels listed on batch documentation
Impurities: Trace levels (<0.5%) of related cyclic amines

First Aid Measures

Inhalation: Remove person to fresh air, monitor for breathing difficulty, provide artificial respiration if breathing stops, seek medical attention for any persistent symptoms
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for 15 minutes, seek medical advice if irritation develops
Eye Contact: Rinse eyes with gentle stream of water for at least 15 minutes, hold eyelids open, remove contacts only if easy to do, consult a physician
Ingestion: Rinse mouth with water, do not induce vomiting, give water if fully alert, call poison center or doctor immediately

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam
Unsuitable Media: High-pressure water jets; may spread fire
Specific Hazards: Fire releases toxic fumes of nitrogen oxides, may produce irritating vapors, risk of flashback if vapors ignite
Advice for Firefighters: Wear self-contained breathing apparatus, chemical-resistant suit, approach from upwind, keep containers cool with water spray

Accidental Release Measures

Personal Protections: Use chemical-resistant gloves, eye protection, lab coat, NIOSH-approved respirator if adequate ventilation lacking
Environmental Precautions: Prevent spills from entering drains or waterways, block off drains using absorbent materials, notify authorities in case of significant leak
Methods for Clean-Up: Absorb spill with inert material (sand, sodium bicarbonate), scoop up into chemical waste container, ventilate area, avoid generating dust
Decontamination: Wash spill site with soap solution after pick-up

Handling and Storage

Precautions: Use under fume hood, keep containers tightly sealed, transfer using tools not bare hands, do not breathe dust
Storage Requirements: Store in cool, dry, well-ventilated area, keep away from strong acids, bases, oxidizers, use appropriate secondary containment
Incompatibilities: Avoid storing near oxidizing agents, acids, anhydrides
Handling Notes: Avoid contact with eyes and skin, maintain good housekeeping to limit accidental contamination

Exposure Controls and Personal Protection

Engineering Controls: Chemical fume hood, eyewash station, emergency shower in area
Personal Protective Equipment: Nitrile gloves, lab coat, safety glasses with side-shields, NIOSH-certified respirator where airborne concentrations rise
Environmental Monitoring: Use direct-read monitors if available; maintain below recommended occupational exposure limits if established
Exposure Limits: Not established specifically for this compound, follow general controls for amines or similar organic base compounds
Hygiene: Regularly wash hands, avoid eating or drinking in chemical-handling areas, remove contaminated clothing promptly

Physical and Chemical Properties

Appearance: Clear to light yellow liquid or solid, strong amine odor
Melting Point: Typically around 40–45°C (varies with batch)
Boiling Point: 160–180°C
Flash Point: 65°C (closed cup, estimated)
Solubility: Fully miscible in water and many organic solvents
Vapor Pressure: Low at room temperature
Density: Approximately 0.97–1.01 g/cm³
pH: Basic in solution, depends on strength
Molecular Weight: 114.19 g/mol

Stability and Reactivity

Chemical Stability: Stable under standard conditions (25°C, ambient pressure)
Reactivity: Reacts with strong oxidizers and acids, exothermic reactions possible with acid chlorides
Hazardous Reactions: Avoid contact with agents causing amine nitration or oxidation, possible nitrogen oxide release
Decomposition Products: Thermal decomposition releases ammonia, nitrogen oxides
Incompatible Materials: Chlorinating agents, acid anhydrides, oxidizing substances

Toxicological Information

Acute Toxicity: Harmful if swallowed or inhaled, LD50 not thoroughly studied but structure suggests moderate toxicity like other small alkyl amines
Skin Corrosion/Irritation: May cause skin redness, burns with prolonged exposure
Serious Eye Damage/Irritation: Severe irritation, blurred vision, tearing, possible chemical burns
Respiratory Impact: Inhalation may trigger coughing, headache, labored breathing, drowsiness at high exposure
Carcinogenicity: No evidence from animal or epidemiological studies
Mutagenicity: No data available, general caution advised for primary amines
Chronic Exposure: Prolonged exposure may lead to skin sensitization or chronic respiratory complaints

Ecological Information

Persistence and Degradability: Not expected to bioaccumulate, readily broken down by microbes under aerobic conditions
Toxicity to Aquatic Life: Potentially toxic to aquatic organisms, fish and daphnids at elevated levels
Environmental Mobility: Highly soluble in water, may spread if released into aquatic environment, risk of groundwater contamination
Bioaccumulative Potential: Low
Other Adverse Effects: Possibility of eutrophication if large amounts enter watercourses and promote excessive microbial activity

Disposal Considerations

Waste Treatment Methods: Dispose of via licensed chemical waste contractor, follow local environmental regulations
Container Disposal: Triple rinse and puncture before disposal; label as hazardous
Incineration: Suitable in approved facility with proper scrubbing of off-gases
Other Advice: Never pour down drain or into surface water, collect all residual material and contaminated absorbents for disposal

Transport Information

UN Number: UN2810 (for toxic organic liquids, specific assignment depends on jurisdiction)
Proper Shipping Name: Toxic liquid, organic, n.o.s. (3-Aminohomopiperidine)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Label Requirements: Toxic substance label; keep away from incompatible freight
Special Precautions: Seal tightly, use secondary containment, temperature control during shipping above melting point in hot climates

Regulatory Information

TSCA: Listed or under review, consult country-specific chemical inventories
REACH Status: Pre-registered, requires downstream user assessment for safe use in the EU
DSL/NDSL (Canada): Assessment required for commercial import
OSHA Hazard Class: Eye, skin, respiratory irritant
SARA Title III: Not listed for specific reporting, but general SARA guidelines apply
Other Regulations: Always consult local authorities for updates on chemical handling, follow any workplace safety program requirements concerning toxic and irritant organic bases