Material Safety Data Sheet for 3-Acetylpyrrolidine

Identification

Product Name: 3-Acetylpyrrolidine
Chemical Formula: C6H11NO
CAS Number: 7465-78-1
Synonyms: 1-(3-Pyrrolidinyl)ethanone, 3-Pyrrolidinone, acetylpyrrolidine
Recommended Uses: Laboratory chemical, pharmaceutical intermediate, research applications
Manufacturer/Supplier: Contact details provided by your local supplier
Emergency Contact: Use local poison control or emergency number

Hazard Classification: Eye irritation, skin irritation, possible harmful if swallowed or inhaled
GHS Label Elements: Exclamation mark symbol, signal word: Warning
Hazard Statements: Causes skin and eye irritation, may cause respiratory tract irritation, possible central nervous system effects at high exposures
Precautionary Statements: Avoid breathing dust, fumes, gas, mist, vapors or spray, wash skin thoroughly after handling, use only outdoors or in a well-ventilated area
Main Symptoms: Redness, itchiness, burning sensation, dizziness

Inhalation: Move the person to fresh air, keep them at rest in a position comfortable for breathing, seek medical help if symptoms persist or worsen
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, seek medical assistance if irritation continues
Eye Contact: Flush eyes thoroughly for at least 15 minutes, occasionally lifting upper and lower eyelids, remove contact lenses if possible, get medical attention if discomfort persists
Ingestion: Rinse mouth, do not induce vomiting, call poison control, provide medical aid if needed
Most Important Symptoms: Red or itchy skin or eyes, cough, dizziness, nausea if inhaled or ingested

Suitable Extinguishing Agents: Use dry chemical, foam, carbon dioxide, or water spray for small fires, use water spray for larger spills involved in fire
Unsuitable Agents: Direct water jet could spread chemical
Specific Hazards: Vapors can form flammable mixtures with air, burning generates toxic gases such as nitrogen oxides and carbon monoxide
Firefighter Protection: Wear self-contained breathing apparatus and suitable protective clothing
Precautions: Keep containers cool by spraying with water if exposed to fire, avoid inhaling fumes

Personal Precautions: Evacuate area if necessary, wear gloves and tightly fitting safety goggles, use protective respirator for strong fumes
Environmental Precautions: Prevent further leakage or spillage if safe, do not let product enter drains, soil, or waterways
Cleanup Methods: soak up spillage with inert absorbent materials such as dry sand, transfer residue using tools and properly labeled containers, ventilate area well
Decontamination: Wash area of spill with water and mild detergent

Handling: Use chemical-resistant gloves, avoid touching skin or inhaling vapors, operate under fume hood for lab work, avoid sources of ignition and open flames
Storage: Store below 25°C in a tightly sealed original container, keep away from heat sources, incompatible substances such as strong acids or oxidizers, and direct sunlight
Incompatible Materials: Strong oxidizing agents, reducing agents, acids
Special Advice: Label containers clearly, use secondary containment for bulk storage

Occupational Exposure Limits: No established limits; minimize exposure as a precaution
Ventilation: Use fume hood or local exhaust to keep airborne concentrations below acceptable limits
Hand Protection: Nitrile or neoprene gloves
Eye Protection: Tightly-sealed chemical safety goggles
Skin Protection: Lab coat or apron, long pants, closed shoes
Respiratory Protection: NIOSH-approved respirator for high concentrations or accidental releases
Hygiene Measures: Wash hands immediately after handling, do not eat, drink, or smoke while using chemical

Appearance: Colorless to pale yellow liquid
Odor: Faint amine-like or sweet odor
Melting Point: Not well documented; typically below room temperature
Boiling Point: 177-179°C at atmospheric pressure
Solubility: Miscible with water, ethanol, ether
Vapor Pressure: Low at ambient temperature
Density: Approx. 1.05 g/cm³
pH: Not available for pure substance; expected to be neutral to slightly basic in solution
Flash Point: Above 62°C

Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Avoid contact with strong oxidizing and reducing agents, acids, alkalis
Hazardous Reactions: May release toxic vapors if combusted or strongly heated
Decomposition Products: Nitrogen oxides, carbon oxides, other hazardous fumes under fire conditions
Polymerization: Not expected under normal storage

Routes of Exposure: Inhalation, eye, skin contact, ingestion
Acute Effects: Eye and skin irritation, respiratory irritation, gastrointestinal disturbance
Chronic Effects: Data insufficient, repeated exposure could lead to chronic irritation, possible liver or kidney stress
LD50 (oral, rat): Not well established, estimated to be moderate based on similar compounds
Carcinogenicity: No carcinogenic components known
Mutagenicity: Not expected based on current data
Reproductive Effects: No data available for adverse reproductive effects

Aquatic Toxicity: Harmful to aquatic life with long lasting effects based on similar chemical structures
Persistence: Expected to be readily biodegradable
Bioaccumulation: Low potential in aquatic or terrestrial species
Mobility in Soil: Likely mobile; soluble in water
Further Information: Do not discharge into drains or water courses

Waste Handling: Collect in tightly sealed, properly labeled containers; hazardous waste pickup or permitted chemical disposal contractor
Disposal Method: Incinerate in licensed facility, observe local environmental regulations
Precautions: Do not mix with household waste, avoid leaking containers

UN Number: Not assigned for small quantities; treat as chemical for laboratory transport
Proper Shipping Name: 3-Acetylpyrrolidine
Transport Hazard Class: Not classed as hazardous for most shipping regulations but handle as hazardous chemical in bulk
Packing Group: Not regulated
Special Precautions: Keep containers sealed upright, away from incompatible items, handle with care to avoid breakage during transit

Status: Not specifically listed on major chemical regulatory lists (TSCA, REACH, DSL), treat as general laboratory chemical
Labeling Requirements: Use GHS compliant labels featuring chemical name, hazard pictogram, and relevant safety phrases
Other Requirements: Users should check local regulations regarding handling, storage, and disposal; hazardous substance record-keeping recommended