Product Name: 3-(1-Piperazinyl)-1,2-Benzisothiazole
Chemical Formula: C11H13N3S
CAS Number: 84163-13-3
Synonyms: 1,2-Benzisothiazol-3-ylpiperazine, Piperazine-1-yl-benzoisothiazole
Intended Use: Intermediate for pharmaceutical or chemical research
Supplier Details: Manufacturer or distributor address, contact number, and emergency contact
Recommended Restriction: Not intended for food, drug, or household use
Classification: Harmful if swallowed, may cause skin irritation, may irritate eyes and respiratory tract
Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation)
Precautionary Statements: Do not eat, drink, or smoke when using this product, avoid breathing dust or vapors, wash exposed skin thoroughly after handling, wear protective gloves and eye protection
Other Hazards: Not known to exhibit acute toxicity at low exposure, chronic data is limited, environmental impact unclear
Chemical Name: 3-(1-Piperazinyl)-1,2-Benzisothiazole
Concentration: Greater than 98% pure
Impurities: Trace solvents and unreacted intermediates at less than 2%
Additives: None reported in standard preparation
Mixture: Single substance, not a mixture
Inhalation: Move affected person to fresh air, assist breathing if needed, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with running water for at least 15 minutes, seek medical advice for persistent irritation
Eye Contact: Flush eyes with water for a minimum of 15 minutes, lift eyelids occasionally, seek medical attention immediately if irritation continues
Ingestion: Rinse mouth with water, do not induce vomiting, get medical help
Symptoms of Exposure: Irritation of nose, throat, and lungs, reddening of skin, burning sensation in eyes or mucous membranes, possible headaches or nausea if ingested
Advice to Physicians: Symptomatic treatment, no specific antidote known
Suitable Extinguishing Media: Dry chemical, CO2, water spray, or foam
Unsuitable Extinguishing Media: Strong water jet may spread fire
Hazardous Combustion Byproducts: Carbon oxides, nitrogen oxides, sulfur oxides, possibly toxic fumes
Firefighters Protection: Full protective clothing and self-contained breathing apparatus
Fire/Explosion Hazards: Not especially flammable, but thermal decomposition may release hazardous gases, avoid inhalation of smoke
Personal Protection: Wear chemical-resistant gloves, goggles, and suitable clothing to avoid contact
Environmental Precautions: Keep product from entering drains, soil, or water bodies, use absorbents like sand or vermiculite
Cleanup Methods: Collect spilled solid material with a shovel, sweep up residues, avoid raising dust, dispose according to local regulations
Decontamination: Wash site of release with ample water and detergent, ventilate area thoroughly
Handling: Work in a ventilated area, avoid dust formation, prevent contact with skin, eyes, and clothing, use proper PPE
Safe Storage: Store in a tightly closed original container in a cool, dry, well-ventilated area, keep away from incompatible substances such as strong oxidizers or acids
Other Precautions: Keep containers labeled, store away from food and drinks, restrict access to trained personnel
Exposure Limits: No occupational exposure limits assigned for this compound, minimize exposure by procedural controls
Engineering Controls: Local exhaust ventilation, safety shower, eyewash station
Personal Protective Equipment: Suitable chemical-resistant gloves (nitrile or neoprene), lab coat, safety goggles, in case of dust generation use NIOSH-approved respirator
Hygiene Measures: Wash hands after handling, do not eat or drink in working areas, remove contaminated clothing before entering eating areas
Environmental Protection: Prevent spillage into the environment, follow proper waste management procedures
Appearance: Off-white to yellowish solid or powder
Odor: Very mild or no characteristic odor
Melting Point: Approximately 110–115°C
Boiling Point: Decomposes before boiling
Vapor Pressure: Not determined
Solubility: Slightly soluble in water, better solubility in organic solvents like DMSO, DMF, ethanol
Density: Approx. 1.18 g/cm³
pH: Not available
Other Data: No explosive properties, no oxidizing properties, stable under ordinary conditions
Stability: Chemically stable under recommended handling and storage
Reactive With: Strong oxidizers, strong acids
Hazardous Reactions: No hazardous polymerization predicted
Decomposition Products: Thermal breakdown produces carbon oxides, nitrogen oxides, and sulfur oxides
Conditions to Avoid: Direct sunlight, moisture, extremes of temperature, strong oxidizing agents
Acute Toxicity: Oral LD50 data not fully established for humans, based on structure may cause moderate toxicity
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: Irritation, nausea, drowsiness, redness of skin or eyes
Chronic Exposure: Long-term effects not thoroughly studied
Carcinogenicity: Not classified as carcinogen based on current information
Mutagenicity: No mutagenicity records in standard databases
Reproductive Toxicity: No known reproductive effects
Target Organs: Data insufficient, but similar chemicals mainly irritate skin and respiratory tract
Ecotoxicity: Not enough data for precise ecotoxicity, avoid release into soil, waterways, or storm drains
Persistence and Degradability: Degradation products unknown, may persist in environment
Bioaccumulation Potential: Low to moderate based on molecular structure, no fish or aquatic organism data
Mobility in Soil: No available soil mobility studies
Other Adverse Effects: Take extra care with disposal, compound has potential to impact aquatic systems if released in large amounts
Waste Disposal: Dispose as hazardous chemical waste in accordance with local, regional, and national regulations
Contaminated Packaging: Empty containers should be rinsed before disposal or recycling, never reuse unwashed packaging
Methods of Disposal: Incineration preferred for larger quantities, small amounts can go through chemical waste stream after neutralization if allowed by regulations
Precautions: Do not release to environment, avoid direct contact during discard
UN Number: Not assigned
UN Proper Shipping Name: Not regulated as a hazardous material by current transport standards
Transport Hazard Class: Not applicable
Packing Group: Not regulated
Environmental Hazards: No classification for environmental hazard
Special Precautions: Avoid breakage or spillage during transit, keep container tightly closed
TSCA Status: Not listed
DSL/NDSL (Canada): Not listed
REACH (EU): Not registered, potential use limited to research
OSHA Hazards: Irritant based on hazard identification
Label Elements: Contains safety warnings, handling precautions, emergency numbers
Other Regulations: Not considered controlled, but observe all applicable safety, transport, and environmental rules at workplace
Worker Protection Standard: Use recommended personal protective equipment and training
