Product Name: 2-Thiopheneethylamine
Synonyms: 2-(2-Thienyl)ethylamine; 2-Thienylethylamine
Chemical Formula: C6H9NS
CAS Number: 5699-90-7
Recommended Use: Chemical research, industrial synthesis, laboratory reagent
Supplier Details: Always check the most up-to-date contact information from your chemical provider, as these can differ by distributor. For university labs, reach out to your EHS office for official records.
Emergency Contact: Refer to national poison control center; for US, call 1-800-222-1222.
Classification: Flammable liquid, irritant, acute toxicity (oral, dermal, inhalation)
Hazard Statements: Catches fire easily, can cause respiratory irritation, leads to skin and eye irritation, may be harmful if swallowed or inhaled, can cause lasting harm if not handled carefully
Pictogram(s): GHS02 (Flame), GHS07 (Exclamation Mark)
Signal Word: Warning
Precautionary Statements: Avoid breathing vapor or mist, work in well-ventilated space, keep away from sparks, no smoking near material, avoid contact with skin and eyes, wash thoroughly after handling
Chemical Identity: 2-Thiopheneethylamine
CAS Number: 5699-90-7
Concentration: 99% or higher in research grade samples, no major impurities identified for common suppliers
Substance Type: Pure substance — not a formulation or mixture, information applies to the core chemical itself
Inhalation: Move outside to fresh air, check for breathing, give oxygen if breathing is difficult, get medical help straight away
Skin Contact: Take off contaminated clothing, rinse skin with running water for at least 15 minutes, seek medical attention if irritation continues
Eye Contact: Rinse eyes carefully with water for at least 15 minutes, keep eyelids apart and move eyeballs, look for help from an eye doctor if symptoms show up
Ingestion: Rinse mouth with water, do not force vomiting, monitor for symptoms — nausea, dizziness, shortness of breath — get medical help right away
Advice for Doctor: Keep observation up for possible delayed symptoms, help with airway support if patient inhaled fumes, symptomatic support recommended
Suitable Extinguishing Media: Use alcohol-resistant foam, carbon dioxide, dry chemical, or water spray
Unsuitable Media: Direct, heavy water jets could spread burning liquid, stick to misting or wide spray
Specific Hazards: May produce toxic fumes like sulfur oxides, nitrogen oxides, carbon monoxide under fire
Protective Equipment: Use full protective suit and self-contained breathing apparatus, stay upwind and avoid vapor
Firefighting Tips: Cool containers with water even after fire goes out, keep runoff away from drains or waterways, keep all ignition sources out of perimeter
Personal Precautions: Wear gloves, splash-proof goggles, lab coat, and NIOSH-rated respirator
Environmental Precautions: Keep spills out of drains and soil, notify local authorities if large contamination risk
Cleanup Methods: Collect liquid with absorbent (vermiculite, sand), keep chemical wastes in proper labeled containers, ventilate the area, wash site with copious water after cleanup, check all materials and tools for contamination before disposal
Handling Advice: Always work with good air flow, avoid breathing vapors, seal containers tight, keep away from open flames or sparks, don't eat, drink, or smoke near chemicals, wash hands thoroughly before touching eating utensils or facial area
Storage Requirements: Store in cool, dry, and well-ventilated place, away from sunlight, tightly closed in original, compatible containers, separate from strong oxidizers and acids, label containers clearly
Special Storage Needs: Fireproof storage recommended for higher quantities, minimize on-hand storage to what’s needed for immediate work
Engineering Controls: Laboratories should use chemical fume hoods for all manipulations, general room ventilation not enough, fail-safes for spill and splash
Personal Protective Equipment: Nitrile gloves for hand protection, tight-seal eye protection, flame-resistant lab coat
Respiratory Protection: Use half-mask respirator when working outside a fume hood or during spills, cartridge selection based on chemical vapor, check guidance from EHS office
Work Hygiene: Wash hands after working, remove and clean clothing before reuse, restrict access to trained users only
Appearance: Colorless to light yellow oily liquid
Odor: Faint amine-like; sulfurous
Melting Point: About -10°C
Boiling Point: Around 225°C (estimate, may vary depending on source)
Flash Point: 103°C
Solubility: Mixes well with ethanol, ether; slight solubility in water
Density: 1.13–1.16 g/cm³
Vapor Pressure: Low, under standard lab conditions
pH: Not applicable (neutral organic liquid)
Chemical Stability: Stays stable at normal temperatures and pressures, should be protected from moisture and prolonged air exposure
Conditions to Avoid: Heat, flames, ignition sources, direct sunlight, static discharge
Incompatible Materials: Strong oxidizers (nitric acid, peroxides), acids, acid chlorides
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon monoxide or dioxide
Acute Toxicity: May cause irritation to eyes, skin, and respiratory tract, LC50/LD50 data limited; avoid all unnecessary contact
Chronic Effects: Prolonged or repeated exposure might heighten risk for liver, kidney, or nervous system issues
Possible Routes of Entry: Inhalation, skin and eye absorption, ingestion
Symptoms of Overexposure: Giddiness, headache, drowsiness, Nausea, respiratory or eye discomfort
Carcinogenicity: No established classification from NTP, IARC, OSHA, or ACGIH
Ecotoxicity: Harmful to aquatic life if released in bulk, requirements for keeping out of water sources
Mobility: Slow to moderate in soil and groundwater due to partial water solubility
Persistence and Degradability: Not expected to be readily biodegradable; takes time for breakdown in environment
Bioaccumulation: Potential for minor accumulation in aquatic organisms
Other Adverse Effects: Encourage spill prevention; even small lab spills add up in scale over years
Disposal Methods: Collect waste in sealed, labeled bottles as hazardous organic waste, never flush down drain
Contaminated Packaging: Empty containers should be triple-rinsed before discarding or sent for approved chemical recycling
Local Regulations: Follow institutional, state, and national chemical waste handling standards — disposal through licensed waste contractor only
UN Number: Check carrier and DOT guidance; this material is not currently listed on standard UN tables but should be shipped as a hazardous organic liquid
Transport Hazard Class: 3 (Flammable liquid)
Proper Shipping Name: Organic liquid, n.o.s. (contains 2-Thiopheneethylamine)
Packing Group: III (lower danger)
Environmental Hazards: Not listed as marine pollutant, yet spills in transit must be reported, classify as flammable for all ground and air shipments
Transport Precautions: Cushion against shock, do not ship with strong oxidizers, separate small quantity shipping from bulk drums, use tough containers with secondary containment in trucks or planes
Global Inventories: Verify current status in TSCA (US), EINECS (EU), DSL (Canada), ENCS (Japan), other regional lists
SARA Title III (Sections 302/313): Not specifically listed, but any spill must be reported promptly if administered at a large scale
OSHA Standards: Handle using chemical hygiene protocol for hazardous research chemicals
Labeling Requirements: GHS/OSHA compliant with clear identification, hazard pictograms, signal word, and precautions
State and Local Laws: Review state-specific chemical handling rules, keep updated MSDS and emergency procedures readily available for all work with amines and sulfur organics
