Product Name: 2-Thiophen-2-Ylpropanoic Acid
Chemical Formula: C7H8O2S
CAS Number: 58546-89-7
Synonyms: Alpha-Methyl-2-thiopheneacetic acid; 2-(2-Thienyl)propionic acid
Recommended Use: Laboratory research, pharmaceutical intermediate
Supplier Details: Information found on purchase documentation
Emergency Contact: Refer to local guidelines; usually a 24-hour emergency phone line for chemical incidents
Manufacturing Date and Batch Number: Refer to packaging or supplier documentation to trace product information during incidents
GHS Classification: Skin irritation (Category 2), Eye irritation (Category 2A), Acute toxicity - oral (Category 4)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation; Harmful if swallowed; May cause respiratory irritation
Pictograms: Exclamation mark
Routes of Exposure: Eyes, skin, ingestion, inhalation
Symptoms: Redness, itching, burning sensation, coughing, nausea, headache; more severe exposure can cause vomiting or breathing difficulty
Precautionary Statements: Avoid contact with skin and eyes; use only outdoors or in well-ventilated spaces; wash hands thoroughly after handling
Chemical Name: 2-Thiophen-2-Ylpropanoic Acid
Common Name: 2-(2-Thienyl)propionic acid
Purity: 97% or higher as typically supplied for laboratory use
Impurities and Stabilizing Additives: Trace organic solvents depending on batch; check supplier COA for specifics
Formula: C7H8O2S
Molecular Weight: 156.20 g/mol
Chemical Group: Thienylacetic acid derivative
Concentration: Product is provided as pure substance without mixture; laboratory blends will list additional components
Inhalation: Move person to fresh air; keep at rest; seek medical attention if symptoms worsen; respiratory distress requires urgent medical evaluation
Skin Contact: Remove contaminated clothing; rinse exposed area with water for at least 15 minutes; use soap to help remove chemical from skin; seek medical attention if irritation develops or persists
Eye Contact: Rinse cautiously for several minutes; remove contact lenses if present and easy to do; continue rinsing; seek medical advice if irritation continues
Ingestion: Rinse mouth with water; do not induce vomiting unless directed by a medical professional; seek medical attention immediately
Most Important Symptoms: Burning, irritation, redness, nausea; in case of high exposures, treat as potential chemical poisoning
Immediate Care and Special Treatment: Symptomatic treatment in a medical facility may be required; bring MSDS to hospital for chemical-specific handling
Suitable Extinguishing Media: Dry chemical, CO2, foam, or water spray; avoid using strong water jets as chemical can be water-reactive in some forms
Hazards During Fire: Combustion may produce harmful gases such as sulfur oxides, carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective clothing to prevent exposure to fumes
Special Procedures: Remove containers from fire if safe to do so; keep area ventilated; douse small fires with extinguishing medium; stay upwind to avoid fumes
Specific Hazards: Overheating containers may cause rupture or violent reaction due to pressure buildup
Personal Precautions: Restrict access; wear gloves, protective clothing, and safety goggles; ventilate area
Protective Equipment: Nitrile gloves, chemical splash goggles, lab coat, and if required, NIOSH-approved respirator
Environmental Precautions: Prevent product from entering drains, watercourses, or soil to avoid harmful ecological impact; report significant releases to local authorities
Cleanup Methods: Absorb spill with inert material such as sand or vermiculite; collect in sealed container for disposal; decontaminate area with soap and water
Further Handling: Dispose of cleanup materials in accordance with local regulations; ventilation and thorough cleaning reduce future risks
Handling: Avoid skin and eye contact; use laboratory fume hood or exhaust for processing; do not eat, drink, or smoke in areas where product is handled
Storage Conditions: Store in tightly sealed container; keep in a cool, dry, and well-ventilated place; protect from heat, direct sunlight, and incompatible substances (like strong oxidizers)
Container Materials: Use chemically resistant bottles such as glass or HDPE; keep away from unsupported metals
Storage Temperature: Ambient room temperature offers optimal stability; refrigeration may be necessary for longer-term storage as per supplier recommendations
Exposure Limits: Not established by OSHA, ACGIH, or NIOSH; minimize all unnecessary exposure
Ventilation: Use local exhaust or fume hood; never process in enclosed or poorly ventilated spaces
Personal Protective Equipment: Splash goggles, nitrile gloves, lab coat, long pants, closed-toe shoes; if there’s risk of inhalation, use a half-face or full-face respirator suitable for organic vapors
Hygienic Measures: Wash hands thoroughly after handling; do not touch face, eyes, or mouth before washing; change contaminated clothing immediately
Emergency Eye Wash and Shower: Access should be available in work area in case of accidental eye or skin contact
Physical State: Solid
Appearance: Off-white to pale beige crystalline powder
Odor: Slight, characteristic sulfurous smell
pH: 2-4 (1% aqueous solution)
Boiling Point: Information partial or not available; decomposition likely before boiling
Melting Point: 61–64°C
Solubility: Moderately soluble in water, more soluble in ethanol, acetone
Density: 1.19 g/cm³ at 25°C
Vapor Pressure: Data not available; considered low at room temperature
Partition Coefficient (log Kow): Not experimentally established
Evaporation Rate: Non-volatile solid; negligible rate
Flammability: Not classified as highly flammable but combustible under fire conditions
Other Important Details: Decomposition produces toxic fumes, particularly under fire or improper heating
Chemical Stability: Stable under standard laboratory conditions; degradation may occur with improper storage or prolonged exposure to air
Conditions to Avoid: Excessive heat, moisture, strong oxidizing conditions; exposure to inert environments helps preserve integrity
Incompatible Materials: Strong oxidizers, strong acids, alkalis; reactive metals
Hazardous Decomposition Products: Under heating or combustion, releases sulfur oxides, carbon monoxides, and potentially toxic organic fragments
Polymerization: Product does not tend to polymerize under standard conditions
Acute Toxicity: LD50 (oral, rat): estimated between 300-2000 mg/kg; harmful if ingested
Skin Corrosion/Irritation: Moderate risk; may cause irritation, redness, swelling, itching
Serious Eye Damage/Irritation: Causes irritation; exposure can result in tearing, redness, pain
Respiratory Sensitization: May lead to coughing, respiratory discomfort, or aggravated symptoms in sensitive individuals
Chronic Effects: Limited chronic toxicity data; safe laboratory practices reduce long-term risk
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No data supporting classification as a carcinogen or mutagen; not listed by IARC, NTP, OSHA
Other Health Effects: Extensive contact or inhalation can cause headache, nausea, dizziness; gastrointestinal symptoms likely after accidental ingestion
Ecotoxicity: Harmful to aquatic organisms; avoid release to the environment
Persistence and Degradability: Moderate; environmental breakdown influenced by microbial activity and photolysis, but persistence possible in low-oxygen soils
Bioaccumulative Potential: Limited data; likely low to moderate based on structure and water solubility
Mobility in Soil: Moderate; run-off possible after spillage, particularly in high-rainfall settings
Other Adverse Effects: Significant spills contaminate waterways and disrupt animal and plant life; strict spill containment and environmentally conscious disposal protect local ecosystems
Disposal Method: Collect and place in tightly sealed, labeled hazardous waste containers for chemical incineration at licensed facility
Uncleaned Packaging: Rinse with appropriate solvent (water, ethanol) before disposal; follow institutional guidelines for label removal and waste characterization
Sewage Disposal: Never dispose of down drain or in regular trash
Local Regulations: Follow national and local regulations for disposal of hazardous chemicals; check for special labeling or export restrictions
Contaminated Materials: Decontaminate glassware and tools using mild detergent and copious clean water; conduct disposal under fume hood for safety
UN Number: Not assigned
Transport Hazard Class: Not classified as hazardous under most transport regulations; laboratory quantities transported under packing group III protocols
Packing Group: Group III (lowest hazard substances)
Environmental Hazards: Not classified as marine pollutant but large spills are harmful
Special Precautions: Ship in segregated packaging, secure against shifting, and protect from sunlight or moisture; always provide MSDS documentation during transit
Safety, Health, and Environmental Regulations: Product not listed on major regulatory inventories as a controlled substance; standard chemical hygiene applies
Right-to-Know Information: Some states (California, New Jersey) require specific labeling for laboratory chemicals
OSHA Status: Not specifically regulated; general laboratory hygiene rule applies
Hazard Symbols: GHS exclamation mark
International Inventories: Verify registration status in local chemical inventories (TSCA, EINECS/ELINCS, DSL, AICS)
Other Regulatory Details: Always check up-to-date local rules for research use, commercial transactions, and shipping/export
