Product Name: 2-Thienylacetic Acid
Chemical Formula: C6H6O2S
CAS Number: 1478-61-1
Synonyms: 2-Thiophenylacetic Acid, α-Thienylacetic Acid
Recommended Use: Chemical intermediate, research, and laboratory reagent
Supplier Information: Contact details of the manufacturer or distributor including address, phone number, and emergency contact are required on the label
Emergency Contact: Local poison control center or manufacturer’s emergency phone
GHS Classification: Acute Toxicity (Oral) Category 4, Skin Irritation Category 2, Eye Irritation Category 2A
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust or fumes, wash hands thoroughly after handling, wear appropriate protective equipment such as gloves and eye protection, do not eat, drink, or smoke while using
Other Hazards: Dust may form explosive mixtures with air, irritates respiratory tract if inhaled at high concentrations
Chemical Name: 2-Thienylacetic Acid
Concentration: ≥99% (as supplied)
Impurities: Typically contains less than 1% unidentified organic impurities and possible trace synthesis byproducts, all of which are not considered to alter the classification of the substance
Inhalation: Remove exposed individual to fresh air, keep at rest, seek medical attention if symptoms persist, monitor breathing
Skin Contact: Immediately flush contaminated area with water for several minutes, remove contaminated clothing, consult physician if irritation develops or persists
Eye Contact: Rinse cautiously with water for at least 15 minutes while holding eyelids open, remove contact lenses if present and easy to do, seek medical guidance if eye irritation occurs
Ingestion: Rinse mouth with water, do not induce vomiting, never give anything by mouth to an unconscious person, get medical advice
Symptoms: Burning sensation, rash or redness, nausea, headache, blurred vision or irritation; seek further medical help for delayed or ongoing effects
Suitable Extinguishing Media: Use alcohol-resistant foam, dry chemical, water spray, or carbon dioxide to extinguish
Unsuitable Extinguishing Media: Direct streams of water may cause spread of chemical fire
Specific Hazards: Release of hazardous gases such as carbon oxides and sulfur oxides may occur during combustion
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Recommendations: Avoid inhalation of combustion products, keep containers cool with water spray if exposed to fire, evacuate area if necessary due to toxic fumes
Personal Precautions: Restrict access to area, use personal protective equipment, avoid generating dust, ventilate area
Environmental Precautions: Prevent further leakage or spillage if possible, prevent entry into drains, soil, and waterways
Cleanup Methods: Sweep up and place in a suitable, labeled container for disposal, use water spray to reduce dust, wash spill site after material pickup is complete
Disposal: Dispose according to local, national, and international regulations, do not sweep into public sewer systems or open environment
Safe Handling: Avoid contact with skin, eyes, and clothing, do not breathe dust, use proper protective equipment, maintain good industrial hygiene by washing hands before breaks and at end of work
Conditions for Safe Storage: Store in a tightly closed, clearly labeled container, place in a cool, dry, and well-ventilated area away from sources of ignition and incompatible materials
Incompatibilities: Strong oxidizers, strong bases, strong acids, and reducing agents
Specific Storage Requirements: Protect from moisture, keep container away from foodstuffs and out of reach of children
Exposure Limits: No established occupational exposure limits noted for 2-Thienylacetic Acid
Engineering Controls: Operate in a fume hood or with adequate local exhaust ventilation to minimize exposure to dust and vapors
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), safety goggles or face shield, lab coat or apron, respiratory protection if dust is generated or concentrations are high
Hygiene Measures: Wash hands and face thoroughly after handling, avoid eating or drinking in work area, do not reuse contaminated clothing until washed
Appearance: White to off-white crystalline powder
Odor: Weak, characteristic, sulfurous
Melting Point: 58 - 64°C
Boiling Point: No data available
Solubility: Moderately soluble in water, soluble in ethanol, methanol, and organic solvents
pH: Not applicable (non-aqueous solution), acidic in water
Vapor Pressure: Negligible at room temperature
Density: Approximately 1.3 g/cm³
Partition Coefficient (Log Kow): 1.33 (estimated)
Flash Point: 170°C (closed cup; estimated)
Auto-Ignition Temperature: Data not available
Decomposition Temperature: May decompose when heated strongly, releasing irritating fumes
Chemical Stability: Stable under normal ambient and anticipated storage conditions
Reactivity: Not reactive under recommended handling and storage conditions
Hazardous Reactions: Strong oxidizing agents may cause violent reaction
Conditions to Avoid: Heat, sparks, open flames, and other sources of ignition
Incompatible Materials: Avoid contact with strong acids, bases, oxidizers, and reducing agents
Decomposition Products: Carbon monoxide, carbon dioxide, sulfur oxides, and organic compounds of unknown toxicity when burned or decomposed at high temperatures
Acute Toxicity: Harmful if swallowed, toxicological data (oral LD50 in rats): 540 mg/kg estimated
Skin Corrosion/Irritation: Causes irritation based on analogy to other thiophene carboxylic acids
Serious Eye Damage/Irritation: Irritating to eyes
Respiratory or Skin Sensitization: Prolonged or repeated exposure may cause skin and respiratory sensitization
Carcinogenicity: No evidence found; not listed by IARC, NTP, or OSHA
Mutagenicity: No data available
Reproductive Toxicity: No available reproductive data; caution advised
Chronic Effects: Prolonged exposure could cause dermatitis or respiratory issues in sensitive individuals
Routes of Exposure: Ingestion, skin and eye contact, inhalation of dust
Ecotoxicity: Limited information; possible toxicity to aquatic life suggested for structurally related thiophene compounds
Persistence and Degradability: Expected to be somewhat biodegradable in soil and water, breakdown may proceed slowly
Bioaccumulative Potential: Limited likelihood of significant bioaccumulation; log Kow reflects moderate mobility
Mobility in Soil: Moderately mobile, potential to leach in soils with low organic matter
Other Adverse Effects: No evidence of ozone depletion or endocrine disruption; proper disposal helps prevent environmental release
Waste Treatment Methods: Collect and containerize material for disposal by incineration in an approved facility or other chemically acceptable procedure matching local regulations
Contaminated Packaging: Handle packaging as hazardous waste; ensure containers are free from residue before recycling or disposal
Precautions for Disposal: Do not dispose in household waste or sewer, comply with all applicable local, state, and national waste management regulations
UN Number: Not classified as hazardous for transport under UN guidelines
Proper Shipping Name: 2-Thienylacetic Acid
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Special Transport Precautions: Package securely to prevent leaks or spillage; keep away from incompatible substances; ensure compliance with all national and international transport regulations
Environmental Hazards: Not classified as marine pollutant or environmentally hazardous substance under transport rules
International Inventory: Listed in TSCA (USA), EINECS/ELINCS (EU), DSL (Canada) and other chemical inventories
OSHA Status: Not specifically regulated under OSHA hazardous substances standard
SARA Title III: Not subject to reporting under Sections 302, 304, or 313
REACH: Exempted as intermediate or registered for specific use, check for most up-to-date status
Labeling Requirements: Label in accordance with GHS and local chemical control laws, including hazard pictograms and signal words
Other Regulations: Users should confirm requirements in their operating jurisdiction, ensure compliance with all workplace safety and environmental protection rules
