Material Safety Data Sheet: 2-Thenoic Acid

Identification

Product Name: 2-Thenoic Acid
Synonyms: Thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid
Chemical Formula: C5H4O2S
Molecular Weight: 128.15 g/mol
CAS Number: 527-72-0
Recommended Use: Research, chemical synthesis, pharmaceutical intermediate
Supplier Details: Chemical manufacturer or distributor contact, address, emergency telephone

Hazard Identification

Classification: Eye Irritant (Category 2A), Skin Irritant (Category 2), Harmful if swallowed (Category 4)
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, may be harmful if swallowed, may cause respiratory irritation
Pictogram: GHS07 (exclamation mark)
Precautionary Statements: Wash skin thoroughly after handling, wear protective gloves/eye protection, avoid breathing dust or fumes, use only outdoors or in well-ventilated area

Composition / Information on Ingredients

Chemical Name: 2-Thenoic Acid
Concentration: ≥99%
CAS Number: 527-72-0
Impurities: Trace amounts of related thiophene derivatives

First Aid Measures

Inhalation: Move the exposed person to fresh air, monitor breathing, offer oxygen if breathing is difficult
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing and launder before reuse, seek medical attention if irritation develops
Eye Contact: Rinse with plenty of water for at least 15 minutes, lift eyelids occasionally, seek immediate medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, get medical attention
Important Notes: Give symptomatic and supportive treatment, medical attention recommended for overexposure

Fire-Fighting Measures

Extinguishing Media: Dry chemical, CO2, alcohol-resistant foam, or water spray
Specific Hazards: Dusts may form explosive mixtures with air, combustion produces carbon oxides, sulfur oxides, irritating fumes
Protective Equipment: Wear self-contained breathing apparatus, full protective clothing
Special Procedures: Keep containers cool with water spray, avoid breathing combustion products, remove all sources of ignition

Accidental Release Measures

Personal Precautions: Evacuate personnel, ventilate area, wear gloves, goggles, and appropriate protective clothing
Environmental Precautions: Prevent runoff to sewers and waterways, inform relevant authorities in case of environmental contamination
Cleanup Methods: Collect material with non-sparking tools, avoid generating dust, sweep up and place in suitable container for disposal, wash spill site after material pick-up

Handling and Storage

Handling: Handle in a chemical fume hood, avoid contact with skin, eyes, and clothing, avoid inhalation of dust, observe good laboratory hygiene
Storage: Store in tightly closed container, keep in a dry, well-ventilated place, protect from moisture, segregate from incompatible materials like oxidizers and bases
Other Requirements: Ensure access to eyewash stations and safety showers in working area

Exposure Controls and Personal Protection

Engineering Controls: Use fume hood, adequate mechanical exhaust, local ventilation
Eye Protection: Chemical splash goggles or safety glasses
Skin Protection: Lab coat, chemical-resistant gloves, long sleeves
Respiratory Protection: NIOSH/MSHA approved respirator if risk of dust inhalation exists
Hygiene Measures: Avoid eating, drinking, or smoking during use, wash hands after handling

Physical and Chemical Properties

Appearance: White to light tan crystalline powder
Odor: Slight odor typical of thiophenes
pH: Not available
Melting Point: 140-143°C (284-289°F)
Boiling Point: Decomposes before boiling
Solubility: Slightly soluble in water, soluble in ethanol and ether
Vapor Density: Not applicable (solid)
Vapor Pressure: Negligible at ambient temperature
Density: Approx. 1.45 g/cm³
Flash Point: Not available
Partition Coefficient (log Pow): Not available
Auto-Ignition Temperature: Not determined

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Incompatible Materials: Strong oxidizing agents, strong bases
Conditions to Avoid: Moisture, heat, open flames, ignition sources
Hazardous Decomposition Products: Produces carbon oxides, sulfur oxides under fire conditions
Possibility of Hazardous Reactions: May react with incompatible materials, no known hazardous polymerizations

Toxicological Information

Acute Toxicity: Data limited, oral LD50 in rats >2,000 mg/kg, low acute oral toxicity
Skin Irritation: May cause irritation or redness
Eye Irritation: Risk of irritation and possible corneal injury
Respiratory Irritation: Dust inhalation may lead to coughing, shortness of breath
Chronic Effects: No adequate long-term studies, no evidence of mutagenicity, carcinogenicity, or reproductive toxicity documented for this compound

Ecological Information

Ecotoxicity: Data scarce; potential low aquatic toxicity based on related thiophene acids
Persistence and Degradability: Likely biodegradable over standard timescales
Bioaccumulative Potential: Expected low, log Kow unknown
Mobility in Soil: May be mobile due to water solubility
Other Adverse Effects: Should avoid uncontrolled releases into environment, follow best chemical disposal practices

Disposal Considerations

Waste Disposal: Dispose via licensed chemical waste contractor in accordance with local and national regulations
Contaminated Packaging: Triple-rinse and dispose as hazardous waste
Physical/Chemical Properties Impeding Disposal: None identified
Special Precautions: Avoid release to environment, do not attempt incineration without proper filtration

Transport Information

UN Number: Not assigned
Proper Shipping Name: Not regulated for transport by land, air, or sea
Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions: Avoid shipment with incompatible materials, handle packages carefully to avoid spills or dust formation

Regulatory Information

TSCA: Listed
DSL/NDSL (Canada): Included
REACH (Europe): Exempted as research chemical, not registered for industrial use
SARA Title III: Not listed as hazardous
California Proposition 65: Not listed
Other Regulations: Local occupational exposure limits may apply, always consult regional legislation for chemical handling and use