Chemists have followed 2-Pyrrolidin-1-ylethanol through decades of lab notebooks, patent filings, and refinements in synthetic methods. Its story begins in postwar chemical research, fuelled by rising demands from both the pharmaceutical and specialty chemical sectors. Early synthetic attempts focused on N-alkylation reactions of pyrrolidine with haloethanols under basic conditions. This discovery made headway in the 1960s and 70s, at a time when organic synthesis chased after intermediates suited for new drugs and advanced materials. Over time, industrial processes moved from exploratory small-batch setups to larger-scale production, optimizing yields and purity thanks to improvements in purification and reaction controls. Demand from the flavors, fragrances, and active ingredient segments gradually shaped the market, drawing more attention to safety records and process repeatability. Today's production lines grew from that legacy, blending old chemistry with newer green protocols and stricter regulatory compliance.
2-Pyrrolidin-1-ylethanol serves as a hard-working intermediate, often mentioned in stories of drug development, coatings chemistry, and specialty solvent production. Its versatility draws from both the alcohol and the amine groups, making it valuable where molecular scaffolds need fine-tuned polarity or specific reactivity. The molecule's structure—pyrrolidine tethered by an ethyl chain to a terminal hydroxyl—lets it fit neatly into a range of chemical transformations fielded by research and manufacturing labs. The chemical's appeal relies partly on this flexibility and partly on the growing need for customizable intermediates in a world that prizes unique molecules for targeted applications. The roll-out of new therapies and materials routinely sees 2-pyrrolidin-1-ylethanol as a featured player, not just as a derivative but as a building block shaping bigger and more complex products.
2-Pyrrolidin-1-ylethanol appears as a clear, colorless to pale yellow liquid at room temperature, with a weak amine-like odor that can linger if handled in a poorly ventilated space. It registers a boiling point in the 100–110°C range at reduced pressure and features significant water solubility, thanks to the hydrophilic character of the alcohol group. A molecular weight close to 115 g/mol makes it manageable in dense reaction mixtures, while its polarity and hydrogen bonding potential open the door for wide miscibility with a variety of organic solvents. The molecule features both nucleophilic amine and electrophilic alcohol regions, often inviting reactions with acids, anhydrides, alkylating agents, and other partners. The dual-reactive nature seldom goes unnoticed by chemical engineers, who look for intermediates that unlock downstream modifications without introducing unwanted complexity.
Producers label commercial-grade 2-pyrrolidin-1-ylethanol with a high purity threshold, typically aiming above 98%. Analytical techniques include NMR, GC-MS, and IR spectroscopy to confirm both purity and identity, with specific reference to melting point (if solid at lower temperatures), refractive index, and water content. Each drum or bottle carries UN-compliant safety labeling referencing hazards, handling recommendations, and storage needs. UN numbers and GHS hazard pictograms reflect known irritancy and toxicity risks—especially for eyes and skin—and provide first aid directives that echo regulatory standards adopted across continents. Storage containers use HDPE or glass, clearly marked to withstand mildly basic amine vapors. Inventory systems in most facilities enter detailed batch numbers and manufacturing dates, keeping traceability on par with standards needed for regulated sectors like pharmaceuticals.
Chemists favor the N-alkylation route, where pyrrolidine reacts with 2-chloroethanol (or similar haloethanols) under mild base, such as sodium carbonate. The reaction calls for careful temperature management in a dry solvent to curb byproduct formation. Extraction with non-polar solvents, followed by distillation under reduced pressure, raises product yields into industrially attractive ranges. Variations sidestep chlorinated substrates by reaching for ethylene oxide or other less hazardous ethylene donors, guided by a desire for fewer hazardous byproducts and less demanding waste disposal. Improvements over the years reduced unwanted polymerization and improved scalability, finding a balance between cost and safety. Some laboratories prefer catalytic hydrogenation pathways, starting from pyrrolidone derivatives, though these require added investment in catalyst recovery and reactor maintenance. No single synthesis dominates outright, but all demand precise execution and a close eye on both throughput and waste reduction.
2-Pyrrolidin-1-ylethanol opens up a world of chemical creativity with both its nucleophilic nitrogen and hydroxyl group. In pharmaceutical research, acylation and alkylation of the nitrogen yield new scaffolds for active molecules. The alcohol moiety gets converted into esters, ethers, or oxidized to yield aldehydes and acids—expanding the range of building blocks from a single starting point. Under strong acid catalysis, ring-closure and rearrangement pathways offer access to rare cyclic species, some of which get tested for medicinal or materials science potential. The molecule's susceptibility to both electrophilic and nucleophilic substitution turns it into a reliable probe for synthetic method development. Skilled chemists exploit this dual reactivity to build libraries of analogs in drug design, especially in search of improved pharmacokinetic traits or novel receptor ligands.
In catalogs and research papers, 2-pyrrolidin-1-ylethanol wears many names: N-(2-Hydroxyethyl)pyrrolidine, 1-(2-Hydroxyethyl)pyrrolidine, and N-(β-Hydroxyethyl)pyrrolidine. Suppliers might refer to CAS Number 1723-99-1 or simply list it under "2-HE Pyrrolidine." Cross-referencing synonyms helps avoid miscommunication in procurement, especially where language differences or regional conventions complicate ordering. Product codes line up on safety data sheets and technical documents to streamline logistics, keeping inventory managers and lab techs in sync. Variant names sometimes highlight the functional group's positions (like hydroxyethyl-pyrrolidine), ensuring that synthetists know exactly what structure to expect on delivery.
Working with 2-pyrrolidin-1-ylethanol calls for personal protective gear: gloves built to resist both solvents and mild bases, protective eyewear to block splashes, and well-ventilated hoods as standard equipment. Vapor and skin irritation risks show up in both lab and production environments, demanding induction and routine safety audits. Facilities store the compound away from oxidizers, acids, and ignition sources since both amines and alcohols can react vigorously under certain conditions. Labels reference regulatory guidelines from OSHA, REACH, and globally harmonized systems, helping to standardize the safe handling procedures wherever the material finds use. Emergency showers, spill kits, and MSDS binders stay within arm’s reach in every facility that takes worker and environmental safety seriously. Disposal routes follow local regulations for amine and alcohol waste, with solvent recycling added to minimize environmental impact.
2-Pyrrolidin-1-ylethanol answers the call across a range of fields. In pharmaceuticals, medicinal chemists build drug candidates with enhanced solubility or improved receptor selectivity. Coatings engineers find value in its solubilizing power, blending it into formulations that need both flexibility and toughness. In analytical chemistry, its dual-functionality makes it ideal as a chiral auxiliary or as a linker in solid-phase synthesis. The fragrance industry borrows it for aroma raw materials, shaping new odor profiles with synthetic precision. The compound even crops up in surface modification of polymers, helping materials scientists tailor interface performance or compatibility with additives. Researchers value this chemical for precisely these reasons—its role as a flexible tool for building out both research models and final products.
Interest in 2-pyrrolidin-1-ylethanol remains high at research benches worldwide because its structure sits at the crossroads of amine and alcohol reactivity. Academic labs thrive on this feature, driving the push for novel synthetic techniques, catalyst systems, and green chemistry routes. Funding agencies support programs that seek to move away from hazardous starting materials, while corporate R&D groups test its derivatives for new roles as corrosion inhibitors, plasticizers, and pharmaceutical intermediates. Software-aided molecular modeling unlocks more sophisticated uses, mapping out possibilities in peptide synthesis and supramolecular assembly. Collaborative patents flow from these efforts, feeding both academic publications and commercial pipelines. The challenge lies in keeping innovation steady while monitoring for unexpected toxicities or reactivity issues at scale.
Toxicologists keep a close watch on pyrrolidine derivatives because systemic effects in mammals often pop up after prolonged or high-level exposure. Standard testing finds eye and skin irritation possible, especially in concentrated form or with repeated contact. Metabolic breakdown pathways in animal studies suggest moderate to low acute toxicity, though subtle nervous system effects sometimes surface after high-dose exposures. In vitro, the chemical interrupts cell membrane function at elevated concentrations, drawing caution for large-scale industrial handling. Environmental toxicity data show rapid biodegradation in aerobic soils and water, but aquatic species still protest at runoff levels above regulatory limits. Continued monitoring at both production and application sites ensures environmental compliance, and periodic updates to safety data sheets reflect any revelations from animal or cell-based tests.
Rising demand for selective building blocks in both old and emerging sectors means 2-pyrrolidin-1-ylethanol will keep earning its spot in catalogues and research feeds. Synthetic chemists continue digging for greener preparation methods, aiming to cut hazardous waste and energy bills. Application prospects depend heavily on further findings from toxicity research and regulatory reviews, especially in fields that touch human health and the environment. Ongoing collaborations between industry and academia promise a steady supply of new derivatizations, paving the way for better polymers, cleaner agrochemicals, and medicines with higher precision. In a global innovation race, the spotlight shines bright on compounds that bring both versatility and manageable risk, and this molecule delivers exactly that blend for now and the foreseeable future.
Years in a chemical lab taught me to respect small molecules that look simple but serve as workhorses behind the scenes. 2-Pyrrolidin-1-ylethanol fits this bill. Chemists love using it as a starting ingredient to build up larger, more complex molecules. Its structure, with both a hydroxyl group and a nitrogen ring, gives it the ability to react in multiple directions and creates room for creativity in pharmaceutical and fine chemical synthesis.
The real benefit for research labs comes from how this compound helps chemists save steps in building medicines or specialty materials. By tying together a nitrogen-based ring and an alcohol, 2-Pyrrolidin-1-ylethanol offers pathways to link up other groups, sometimes in one pot. This shortcut matters. Time, safety, and cost all improve when a chemist can set up a reaction using fewer steps—less waste, fewer risks, and real savings. So, even though you never see this substance in your medicine cabinet, it hides behind the drugs that land there.
If you peek into the development of new medicines, you’ll find that 2-Pyrrolidin-1-ylethanol acts as part of key intermediates. Drug companies value chemical building blocks with versatility, and this one helps unlock new beta-blockers, antifungals, and antiviral molecules. Its structure lets scientists modify it into new forms by attaching different groups. Once, during a custom synthesis run, I watched the team use this compound to help solve a bottleneck in making a promising antibiotic candidate. Its flexibility opened paths that would otherwise have closed, and the project found new life.
This compound doesn’t just play a role in making drugs. Its mix of properties makes it handy for tweaking other substances, serving as a solvent or stabilizer when none of the common types fit the bill. Some folks in chemical manufacturing reach for 2-Pyrrolidin-1-ylethanol when they need to adjust reactivity or solubility without throwing the entire process off balance. For example, it’s used to modify resin systems, which changes how paints or adhesives handle drying and sticking. Sometimes, resin suppliers will rely on it for tailored performance where cheap, standard ingredients fall short.
The flexibility of this compound also shows up in research labs outside pharmaceuticals. Academic projects turning out catalysts, sensors, or advanced polymers sometimes depend on 2-Pyrrolidin-1-ylethanol to bridge gaps that other alcohols or amines can’t. From my grad school days, I remember a project tweaking the wetting properties of new coatings. We hit a block until someone suggested adding a small amount of this compound to the formulation. It made the coating more durable and easier to apply, reminding me that sometimes modest tweaks cause major shifts.
Respect for chemicals never goes out of style. 2-Pyrrolidin-1-ylethanol, like many lab staples, needs careful storage and proper ventilation during use. While it isn’t the most hazardous, gloves and goggles remain a must, and staying updated with safety data sheets keeps everyone on track. These best practices don’t just matter for personal safety—they anchor trust in lab and factory operations. From a regulatory perspective, clear labeling and tracking serve as guardrails to reduce risks both in small batches and industrial runs.
As new industries look for safer solvents and greener chemistry, 2-Pyrrolidin-1-ylethanol gives researchers one more option. Interest keeps rising around reducing waste stream impact and using substances that allow for safer, high-yield transformations. Continued exploration and substitution, guided by fresh data and transparent testing, could push this compound into new roles—especially in processes demanding precision but with lower environmental costs.
Chemistry often feels layered, but sometimes it helps just to visualize a molecule and see how it fits together. 2-Pyrrolidin-1-ylethanol catches your attention right off the bat through its name—it’s a combination of a pyrrolidine ring and an ethanol group. That little bit of information already hints at its chemical makeup.
2-Pyrrolidin-1-ylethanol features two main parts. Imagine a five-membered ring, packed with four carbons and one nitrogen—this is your pyrrolidine. Chemistry textbooks describe it as a saturated ring, but in practical day-to-day work, you’ll notice it brings some stability and flexibility when introduced into molecules.
Then, connected to the nitrogen atom of the ring, there’s an ethanol chain. Ethanol brings in one more carbon and an -OH (hydroxyl) group. So, the molecule sticks together as a two-carbon chain coming off the nitrogen, with its terminal carbon holding the oxygen and hydrogen of the alcohol group.
If you want to sketch it on paper, you’d start with the pyrrolidine ring, tag a nitrogen onto one vertex, and then snake the two-carbon ethanol side chain out of the ring from that nitrogen. The -OH group sits at the end. In terms of text representation, chemists go with this condensed formula:
C6H13NO
Or sometimes it’s written as HOCH2CH2N(C4H8) to emphasize the ethanol and pyrrolidine parts. Its structural formula appears like this:
N—(CH2)4—CH2—CH2—OH
Clarity about molecular structure matters in far more ways than just on paper. From my time working alongside formulation scientists, one truth stands firm: slip-ups or misreads in structure resonate up and down a project, from synthesis through product application.
If the pyrrolidine isn’t in the right spot, or if the ethanol side chain flips somewhere it shouldn’t, the compound’s chemical traits shift—solubility, reactivity, and interaction with other molecules all change. The -OH group on 2-Pyrrolidin-1-ylethanol means it blends water-friendly traits with the unique behavior of a cyclic amine. That has real consequences in medicinal chemistry, where adding or moving a single atom can spell the difference between a brilliant solution and a flop in bioactivity.
Sourcing reliable molecular data stands out as one obvious need. I’ve seen chemical information sites dish out poor representations, which confuses students and throws off newcomers. Better standardized graphical depictions and greater transparency in reference materials could clear up frequent miscommunication.
Those who work with the substance in the lab should confirm everything via up-to-date spectroscopy and analytical chemistry. NMR scanning picks up little deviations that structure diagrams might miss. Combining software modeling and hands-on lab work tightens up accuracy.
Building bridges between well-trained chemists and those new to the field lifts overall confidence and safety when working with molecules like 2-Pyrrolidin-1-ylethanol. Sharing verified models, instead of leaning on old textbook mistakes, helps everyone move forward together.
Most people would never think about 2-Pyrrolidin-1-ylethanol on their daily commute, yet this chemical shows up in more than a lab. You’ll find it in research work, some pharmaceutical manufacturing, even specialty coatings. As with any substance that makes its way into workplaces and storage rooms, it’s worth asking: What does it mean for health and safety? How toxic is it, and are there situations where those risks grow?
Safety Data Sheets from chemical suppliers, along with publicly available research, give this compound a clear warning: it can cause irritation to the skin, eyes, and respiratory tract. If you breathe its vapors or get it on bare skin, the reaction can range from mild redness to coughing and discomfort—and, in a busy work setting, that’s rarely good news.
I spent a few years supporting a college chemistry department, mixing chemicals and managing inventories. Whenever I handled unfamiliar organics, even just opening a bottle, the sharp scents and a tingle on the fingertips kept me alert. Small exposures have a way of sneaking up. 2-Pyrrolidin-1-ylethanol left a twinge in my nose that reminded me not to drop my guard. So many health incidents start with an “it’s probably fine” attitude, ending in surprise emergency visits.
Looking up toxicology reports, there’s limited evidence about chronic or long-term effects, but lack of data isn’t the same as safety. Most regulatory sources still label it as hazardous, not out of fear but because its chemical relatives show potential risks—some related compounds have been flagged for similar irritancy and absorption into the body. Until thorough, independent research fills in the gaps, treating this liquid with caution fits best practices.
Walk into any research facility, and the difference between a well-run and a careless lab comes down to habits: wearing gloves, using goggles, and keeping spills small and contained. It’s tempting to cut corners on ventilation or storage, especially when you’re up against a project deadline, but that’s when mistakes happen.
2-Pyrrolidin-1-ylethanol isn’t among the infamous toxins that demand headlines, but its risks show up most in poor handling. Direct splashes sting. Inhaled vapors can create headaches or worse if exposure runs long. In one case I remember, a co-worker forgot their gloves and brushed the liquid while reorganizing shelves. Itched for hours—a fast reminder that chemical safety doesn’t take breaks.
Regulations set by agencies like OSHA recommend clear labeling, restricted access, and emergency procedures like eyewash stations near where chemicals get used. These measures are not bureaucratic overreach—they’re the result of too many accidents that hurt real people.
Chemistry at any scale blends knowledge with habit. Training and vigilance keep accidents in check. It’s smart to check the latest research, even ask suppliers for updated hazard assessments, instead of coasting on old assumptions. In companies where ‘just in time’ means acting fast, employees trust leadership more if protective gear and up-to-date safety guidance are right there and not just buried in binders.
Chemical safety culture starts in the day-to-day: regular audits, clear procedures, and speaking up when a step is missed. Focusing on these builds trust and reduces risk, whether in a research setting, a small production line, or a storage room full of bottles—especially for substances like 2-Pyrrolidin-1-ylethanol, whose full health profile isn’t yet written.
2-Pyrrolidin-1-ylethanol enters many labs and factories as a modest liquid, clear or sometimes pale yellow, carrying a mild, recognizable odor. On the surface, it blends in among countless organic solvents and reagents. Digging a bit deeper, its chemical structure suggests routes to pharmaceuticals, agrochemicals, and sometimes specialty polymers. Working with it carries unique responsibilities, better learned before mistakes turn minor spills into hazardous events.
I’ve watched solvents and small molecules, like this one, degrade quickly when someone gets lax about the basics. 2-Pyrrolidin-1-ylethanol stays stable in cool, dry, dark spaces. Steady temperature makes a difference. Chemical bonds can break down if bottles ride out temperature swings near lab windows or beside radiators. So, placing it away from heat sources and sunlight protects purity and lengthens shelf life. A fridge might seem like overkill, but even a basic lab cabinet with exhaust does the job if temperatures stay under 25°C.
Moisture is another silent enemy. Just a leaky cap, a humid storeroom, or a spill next to a sink opens doors to slow reactions—not always visible, but sometimes producing acidic fumes or forming layers in the bottle. I’ve seen stickiness or yellowing in forgotten flasks, a sign the container let too much air or water vapor inside. Tight seals save a lot of hassle. Always close the cap tight, wipe down the neck and threads after every pour, and label the date when the bottle gets opened. For larger stocks, splitting into smaller bottles keeps the main supply from constant exposure.
Shelving plays a surprisingly big role. The right shelf supports glass containers and keeps acids, bases, and reactive metals well away. Grouping 2-Pyrrolidin-1-ylethanol with other amines or similar organics reduces mix-ups. Mixing incompatible chemicals on a shelf can set up tiny disasters—especially if accidents turn a cracked bottle into a chemistry experiment. In our lab, separating oxidizers and strong acids from every storage area with solvents became standard after a spill sent two staff hurrying to the eyewash.
Opening a bottle and pouring out a bit always needs proper gloves—nitrile fits best for most people—and splash goggles, even for small volumes. Spills sting and vapors can irritate eyes or skin, especially in crowded labs. Funnels minimize drips. In a manufacturing setting, I’ve watched process operators rely on fume hoods and sealed transfer lines. In smaller operations, working in a well-ventilated space keeps vapors from building up. Never leave the bottle open, even for a few minutes, since air and moisture sneak in quickly.
Organizations like OSHA and the European Chemicals Agency publish data that underlines the importance of controlling exposure. 2-Pyrrolidin-1-ylethanol hasn't earned a notorious reputation like some high-profile chemicals, but repeated skin contact or breathing its vapors brings risk. Health and safety briefings usually point to safety data sheets, but reading between the lines, real-world observations tell you disrespect for the basics—labeling, secondary containment, routine checks—triggers more incidents than rare incompatibilities or technical hazards.
Working with this compound gets safer with a few habits: double-check those labels, keep supplies off the benches unless needed, document all transfers, and don’t improvise with containers. If you run a bigger operation, periodic training and an up-to-date chemical inventory count as core investments—costly if skipped, easy to justify after a minor emergency.
A small bottle of 2-Pyrrolidin-1-ylethanol promises useful results, but only to those who respect the basic rules. Lab work or chemical processing builds on habits that get reinforced by accidents avoided, and good storage and careful handling always prove their importance with time.
2-Pyrrolidin-1-ylethanol isn’t one of those chemicals that gets highlighted in mainstream news. Still, anyone working in research, pharmaceuticals, or fine chemical synthesis will recognize it. I remember the first time I needed this compound for a project—tracking it down took more effort than jotting down a CAS number and clicking ‘order now’. Sourcing specialty chemicals requires more than just luck; you want quality, compliance, and reliable supply.
To find verified suppliers, I always start with established chemical distributors. Companies like Sigma-Aldrich, Thermo Fisher Scientific, and Alfa Aesar typically list 2-Pyrrolidin-1-ylethanol, though stock can fluctuate. Each of these distributors keeps an updated online catalog that gives purity, available grades, storage data, and safety information. Before placing an order, I contact their sales department to confirm inventory, shipping times, and, most importantly, compliance with local regulations.
Some niche or regional suppliers also carry this compound. For researchers outside North America or Europe, it pays to check with firms like TCI Chemicals (Tokyo Chemical Industry) or regional specialty suppliers connected to universities and R&D labs. These vendors often provide smaller amounts suited for bench-scale experiments.
Packaging matters more than it first appears. My experience taught me to look beyond price and check container types and closure systems. 2-Pyrrolidin-1-ylethanol commonly ships in amber glass bottles, usually starting at 25-gram or 100-gram sizes for lab use. Bulk orders for industrial projects sometimes use sealed metal cans or high-density polyethylene containers. Amber glass limits light exposure and helps prevent decomposition, especially during long transit or storage.
Larger pack sizes—like 500 grams or up to several kilograms—aren't always listed online. I’ve had to request custom packing based on project demands. Some vendors offer UN-rated drums with tamper-evident seals, which ensures both compliance and product stability in bulk scenarios.
I learned early that cutting corners with chemicals rarely saves trouble. Buying from verified suppliers ensures each batch comes with a certificate of analysis, which states purity, origin, and lot number. This document becomes vital if a result gets questioned or if regulators check records. Anyone tempted by fly-by-night vendors online risks getting subpar product, mislabeled material, or even legal headaches.
Import rules can tie up otherwise simple orders. Some countries treat precursor chemicals, including 2-Pyrrolidin-1-ylethanol, with suspicion. It pays to ask the supplier about up-to-date export documentation and shipping partners who understand the rules in both origin and destination countries. Delays from customs clearances often trace back to missing or incorrect paperwork.
Solid scientific work relies on transparency and traceable materials. In the early days of chemical research, uneven supplies created endless frustration. Thankfully, today’s suppliers offer traceability, digital access to documentation, and responsive customer service. Sticking with suppliers who value quality and safety makes research smoother—more than once, a well-packaged shipment meant the difference between staying on schedule and a month-long delay.
Anyone looking for 2-Pyrrolidin-1-ylethanol today won’t need to settle for mystery bottles or questionable sources. Responsible vendors put clear product data, safe packaging, and credible paperwork front and center. Those details matter, whether the job is routine or pioneering something new.
| Names | |
| Preferred IUPAC name | 2-(Pyrrolidin-1-yl)ethan-1-ol |
| Other names |
2-(1-Pyrrolidinyl)ethanol 2-Pyrrolidinoethanol 1-(2-Hydroxyethyl)pyrrolidine |
| Pronunciation | /tuː pɪˌrɒlɪˈdiːn wʌn ˈɪl ˈɛθənɒl/ |
| Identifiers | |
| CAS Number | 3433-80-5 |
| 3D model (JSmol) | `3D model (JSmol)` string for **2-Pyrrolidin-1-Ylethanol** (also known as 2-(Pyrrolidin-1-yl)ethanol) is: ``` CCN1CCCC1 ``` (Note: This is the **SMILES** string that can be used for 3D modeling in JSmol or similar viewers.) |
| Beilstein Reference | 81168 |
| ChEBI | CHEBI:34409 |
| ChEMBL | CHEMBL14733 |
| ChemSpider | 11078 |
| DrugBank | DB09475 |
| ECHA InfoCard | Renata; 14,0060 |
| EC Number | 225-118-5 |
| Gmelin Reference | 78138 |
| KEGG | C06083 |
| MeSH | D053211 |
| PubChem CID | 7508 |
| RTECS number | UE3675000 |
| UNII | 5K7C4TQS2S |
| UN number | UN2810 |
| CompTox Dashboard (EPA) | DTXSID5034685 |
| Properties | |
| Chemical formula | C6H13NO |
| Molar mass | 115.17 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Odor | amine-like |
| Density | 1.032 g/mL at 25 °C (lit.) |
| Solubility in water | miscible |
| log P | -0.36 |
| Vapor pressure | 0.0725 mmHg at 25°C |
| Acidity (pKa) | 15.1 |
| Basicity (pKb) | pKb = 5.93 |
| Magnetic susceptibility (χ) | -54.8·10^-6 cm³/mol |
| Refractive index (nD) | 1.464 |
| Viscosity | 23 mPa·s (25 °C) |
| Dipole moment | 2.53 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 274.6 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -258.7 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -3973.8 kJ/mol |
| Pharmacology | |
| ATC code | N07BX02 |
| Hazards | |
| Main hazards | Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
| GHS labelling | GHS07, GHS05 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | H302, H315, H319, H335 |
| Precautionary statements | P280, P305+P351+P338, P337+P313 |
| NFPA 704 (fire diamond) | 2-1-0 |
| Flash point | 86 °C |
| Autoignition temperature | 235 °C |
| Explosive limits | Explosive limits: 1.2–9.5% (in air) |
| Lethal dose or concentration | LD50 (oral, rat) = 3,636 mg/kg |
| LD50 (median dose) | LD50 (median dose) of 2-Pyrrolidin-1-Ylethanol: "500 mg/kg (Rat, oral) |
| NIOSH | SN 2100000 |
| PEL (Permissible) | PEL (Permissible Exposure Limit) for 2-Pyrrolidin-1-Ylethanol: Not established |
| REL (Recommended) | 5 mg/m³ |
