Material Safety Data Sheet (MSDS) for 2-Propyl Pyrazine

Identification

Chemical Name: 2-Propyl Pyrazine
Synonyms: Pyrazine, 2-propyl-; 2-n-Propylpyrazine
CAS Number: 18138-41-7
Molecular Formula: C7H10N2
Molecular Weight: 122.17 g/mol
Recommended Use: Used in fragrances, flavoring, and laboratory chemicals
Supplier: [Insert manufacturer or distributor information]
Contact Details: [Insert emergency contact number and address for supplier]

Hazard Identification

Classification: Irritant for skin, eyes, and respiratory tract
GHS Label: Exclamation mark (irritant)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation; may cause respiratory discomfort if inhaled
Precautionary Statements: Avoid contact with skin and eyes; do not breathe vapor or dust; wear appropriate protective gear
Potential Health Effects: Redness and discomfort in exposed areas; headache and nausea from fumes
Environmental Effects: May cause minor aquatic toxicity if spilled in large quantities

Composition / Information on Ingredients

Main Component: 2-Propyl Pyrazine
Chemical Formula: C7H10N2
Concentration: More than 98% pure
Impurities: Trace organic solvents or by-products; varies based on supplier

First Aid Measures

Eye Contact: Flush eyes with plenty of clean water for at least 15 minutes; remove contact lenses if present
Skin Contact: Wash exposed skin with soap and water; remove contaminated clothing
Inhalation: Move person to fresh air immediately; loosen tight clothing; seek medical advice if symptoms persist
Ingestion: Rinse mouth with water; do not induce vomiting; get medical attention
Notes for Physician: Show this safety data sheet; treat symptomatically

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, or water spray
Unsuitable Extinguishing Media: Strong water jet
Specific Hazards: Vapors may form explosive mixtures with air; combustion releases carbon oxides and nitrogen oxides
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective gear
Advice for Firefighters: Move containers from fire area if possible; cool with water spray; avoid inhaling combustion products

Accidental Release Measures

Personal Protection: Wear gloves, goggles, and protective clothing
Environmental Precautions: Prevent entry into waterways, sewers, and soil
Containment Procedures: Absorb with inert material (e.g., sand or vermiculite); scoop solid spill into covered containers
Cleaning Up: Wash spill site with water and detergent after material pickup is complete

Handling and Storage

Safe Handling: Use in well-ventilated areas; avoid inhalation or skin contact; keep away from heat or ignition sources
Equipment: Use spark-proof tools and explosion-proof equipment
Storage Conditions: Keep tightly closed in a cool, dry place; store in original container; avoid direct sunlight and moisture
Incompatibility: Store separately from strong oxidizers, acids, and alkalis
Packaging Materials: Use amber glass or high-density polymer containers for extended stability

Exposure Controls and Personal Protection

Ventilation: Use local exhaust or adequate general ventilation
Personal Protection: Wear chemical splash goggles, protective gloves (nitrile recommended), and long-sleeved clothing
Respiratory Protection: Use NIOSH-approved respirators if vapor or dust is present above recommended levels
Hygiene Measures: Wash thoroughly after handling; avoid eating or drinking near chemical use
Exposure Limits: No established occupational exposure limits; minimize exposure as much as possible

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Nutty, roasted, earthy
Melting Point: -17 °C
Boiling Point: 185-187 °C
Flash Point: Above 63 °C (closed cup)
Solubility: Slightly soluble in water; soluble in alcohols, esters, oils
Vapor Pressure: Low at room temperature
Density: 0.97 g/cm³ at 20 °C
pH: Not applicable (neutral organic compound)
Viscosity: Low at room temperature
Partition Coefficient (log Kow): Estimated at 1.62

Stability and Reactivity

Chemical Stability: Stable under normal conditions of storage and use
Hazardous Reactions: No hazardous polymerization expected
Incompatible Materials: Strong oxidizing agents, acids, and bases
Decomposition Products: Combustion may create carbon monoxide, carbon dioxide, and nitrogen oxides
Conditions to Avoid: Extreme heat, direct sunlight, and open flames
Storage Life: Up to two years if kept sealed and away from incompatible substances

Toxicological Information

Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Effects: Eye and skin irritation, headache or dizziness from high vapor concentrations
Chronic Effects: No long-term data available; experimental data suggest low toxicity for repeated exposure
LD50 (Oral, Rat): Estimated above 2000 mg/kg
Sensitization: No evidence for sensitizing properties in available research
Carcinogenicity: Not listed as carcinogen by IARC, NTP, or OSHA
Mutagenicity: No reported mutagenic effects
Reproductive Toxicity: No reproductive toxicity found in available animal studies

Ecological Information

Persistence and Degradability: Expected to be biodegradable over time in soil and water environments
Bioconcentration Potential: Low risk for bioaccumulation
Ecotoxicity: Slightly harmful to aquatic species at high concentrations; fish LC50 (estimated) above 100 mg/L
Mobility in Soil: Moderately mobile in soil based on estimated log Kow and solubility
Other Adverse Effects: Releases to environment should be avoided to reduce risk to aquatic systems

Disposal Considerations

Disposal Methods: Dispose of contents and container through a licensed waste disposal contractor
Contaminated Packaging: Clean and recycle or dispose as hazardous waste
Recommendations: Do not flush into drains or natural waterways; incineration in approved facility is recommended
Regulatory Requirements: Check local, state, and national regulations before disposal

Transport Information

UN Number: Not regulated
Proper Shipping Name: Not classified as dangerous for transport
Packaging Group: Not applicable
Transport Labels: None required
Special Precautions: Keep containers securely closed and upright during transport; avoid stacking heavy loads on top

Regulatory Information

Listing Status: Not specifically listed under US TSCA, EU REACH, or Australia AICS
SARA Section 302/304 – Extremely Hazardous Substances: Not designated
SARA Section 311/312 – Hazard Categories: Immediate health hazard (irritation)
SARA Section 313 – Toxic Chemicals: Not regulated
California Proposition 65: Not included
Other Regulations: Observe all relevant federal, state, and local regulations for chemical handling
Label Requirements: Follows GHS standards for hazard communication and precautionary measures