Product Name: 2-Piperidin-2-ylethanol
Synonyms: 2-Hydroxyethylpiperidine, 2-(2-Hydroxyethyl)piperidine
CAS Number: 52706-40-6
Recommended Use: Chemical intermediate, laboratory reagent
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GHS Classification: Acute toxicity – Oral (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A)
Label Elements: Warning symbol, exclamation mark
Hazard Statements: Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: Avoid inhaling dust/vapors. Wash hands thoroughly after handling. Wear protective gloves and eye protection.
Physical Hazards: No significant physical hazards identified.
Health Hazards: May cause irritation to respiratory system, eyes, and skin. Ingestion may cause gastrointestinal discomfort.
Environmental Hazards: Toxic to aquatic life with long lasting effects.
Chemical Name: 2-Piperidin-2-ylethanol
Synonyms: 2-Hydroxyethylpiperidine
CAS Number: 52706-40-6
Concentration: ≥98%, single component
Impurities: No hazardous impurities at significant concentrations
Inhalation: Move to fresh air. Give artificial respiration if breathing has stopped. Seek medical help for symptoms like coughing or dizziness.
Skin Contact: Rinse skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Immediate washing reduces risks of chemical burns or irritation.
Eye Contact: Rinse cautiously with water for 15 minutes while holding eyelids open. Remove contact lenses if present. Seek prompt medical advice for redness, pain, or vision changes.
Ingestion: Rinse mouth thoroughly. Do not induce vomiting without medical advice. Call a poison center or doctor if discomfort develops.
General Advice: Call a physician if feeling unwell or symptoms persist. Always have access to eye wash stations and emergency showers in areas where this compound is used.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide if fire occurs nearby.
Unsuitable Extinguishing Media: Do not use strong water jets.
Specific Hazards: On decomposition, releases vapors such as nitrogen oxides, carbon monoxide, carbon dioxide.
Protective Equipment: Wear self-contained breathing apparatus and full protective gear.
Special Procedures: Cool exposed containers with water spray. Prevent runoff from entering drains or watercourses.
Combustion Products: Toxic gases may be released during fires; ensure responders are aware of this risk.
Personal Protection: Avoid dust or vapor formation. Ensure adequate ventilation. Wear appropriate personal protective equipment.
Environmental Precautions: Prevent further leakage or spillage if safe. Prevent entry into waterways, sewers, and confined spaces.
Containment and Cleanup: Use inert absorbent material like sand or vermiculite to soak up spilled material. Sweep up and place in a suitable closed container for disposal. Clean contaminated surfaces with water and detergent to eliminate residue.
Emergency Procedures: Evacuate unnecessary personnel. Ventilate affected area. Use non-sparking tools for clean-up.
Safe Handling: Avoid breathing dust, vapor, mist, or spray. Use only with adequate ventilation. Avoid contact with skin, eyes, and clothing. Do not eat, drink, or smoke while using this chemical.
Storage Conditions: Store tightly closed in a cool, dry, well-ventilated area. Keep container away from incompatible materials such as strong oxidizers or acids. Avoid temperature extremes.
Incompatible Materials: Strong acids, strong oxidizing agents
Workplace Hygiene: Wash thoroughly after handling, especially before eating or drinking. Remove contaminated clothing promptly.
Occupational Exposure Limits: No specific occupational exposure limits established. Use common workplace threshold limits for similar organic amines as guidance.
Engineering Controls: Use mechanical exhaust or local ventilation to minimize exposure to vapors or dust.
Personal Protective Equipment (PPE): Wear chemical-resistant gloves, safety goggles, lab coats, and appropriate respiratory protection if ventilation is insufficient.
Environmental Controls: Prevent product from reaching drains or water bodies during use or cleaning.
Hygiene Measures: Wash hands and face before breaks and at end of work. Provide eyewash stations and safety showers.
Appearance: Colorless to pale yellow liquid
Odor: Faint, amine-like
Melting Point: 25–28°C
Boiling Point: 254°C at 760 mmHg
Flash Point: 117°C (closed cup)
Solubility: Miscible with water
Relative Density: 1.04 g/cm³
Vapor Pressure: 0.018 mmHg at 25°C
Partition Coefficient: log Kow estimated 0.3
pH: Not available
Vapor Density: Not available
Viscosity: Not established
Evaporation Rate: Not available
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Generally unreactive with common materials, but can undergo exothermic reactions with strong oxidizers.
Conditions to Avoid: Heat, flame, other sources of ignition, contact with incompatible chemicals.
Incompatible Materials: Strong acids, oxidizing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide may form upon combustion or thermal decomposition.
Polymerization: No dangerous polymerization expected.
Routes of Exposure: Inhalation, ingestion, skin and eye contact.
Acute Toxicity (Oral): LD50 (rat) >200 mg/kg
Skin Corrosion/Irritation: Causes skin irritation.
Eye Damage/Irritation: Causes serious eye irritation.
Respiratory Sensitization: Not classified as respiratory sensitizer.
Skin Sensitization: No known skin sensitizing effects.
Germ Cell Mutagenicity: Not classified.
Carcinogenicity: No components listed as carcinogenic by IARC, NTP, or OSHA.
Reproductive Toxicity: No conclusive data on reproductive effects.
STOT – Single/Repeated Exposure: May irritate respiratory system at high concentrations.
Aspiration Hazard: Not established.
Aquatic Toxicity: Data not available, but similar compounds show moderate toxicity to aquatic organisms.
Persistence and Degradability: Not expected to be readily biodegradable.
Bioaccumulative Potential: Low, based on low log Kow.
Mobility in Soil: High mobility expected due to water solubility.
Other Adverse Effects: May cause harmful short-term effects to aquatic life if released in large quantities.
Precautions: Avoid uncontrolled release to water bodies or sewage systems.
Disposal Methods: Dispose of in accordance with local, regional, national, and international regulations. Incinerate in an approved facility if possible.
Contaminated Packaging: Triple rinse containers, then offer for recycling or dispose of as hazardous waste.
Special Precautions: Do not discharge into the environment. Consult waste management professionals to determine proper routes of disposal.
UN Number: Not regulated for transport under current international guidelines.
Proper Shipping Name: Not classified as dangerous good.
Transport Hazard Classes: Not applicable
Packing Group: Not assigned
Marine Pollutant: Not identified as marine pollutant
Special Precautions for User: Avoid transport with food and feedstuffs. Ensure containers are tightly sealed and labeled.
Environmental Hazards: Prevent release during transport to minimize risk of environmental impact.
US TSCA Inventory: Listed or in compliance
EU REACH Status: Registered or pre-registered substances
OSHA Hazard Communication: Classified as hazardous
SARA Title III Section 313: Substance not subject to reporting
California Proposition 65: This compound is not listed
Canadian WHMIS Classification: Classified as hazardous based on available information
Other Regulations: Comply with all applicable workplace, health, and safety regulations governing handling and use of chemicals
