Product Name: 2-Piperazin-1-ylethanol
Chemical Formula: C6H14N2O
CAS Number: 103-76-4
Synonyms: 1-(2-Hydroxyethyl)piperazine, 2-(1-Piperazinyl)ethanol
Recommended Use: Intermediate for pharmaceuticals, corrosion inhibitors, synthesis applications
Manufacturer Information: Supplier details available on packaging and invoice
Emergency Phone: Contact local poison control or the supplier’s emergency line
GHS Classification: Skin irritation (Category 2), Serious eye damage/eye irritation (Category 1)
Signal Word: Danger
Hazard Statements: Causes skin irritation, causes serious eye damage
Pictograms: GHS07 (Exclamation mark), GHS05 (Corrosion)
Precautionary Statements: Wear gloves/eye protection; wash hands thoroughly after handling; if in eyes, rinse cautiously with water for several minutes and seek medical attention
Other Hazards: May be harmful if inhaled or swallowed, possible respiratory tract irritation
Chemical Identity: 2-Piperazin-1-ylethanol
Purity: >98%
Impurities: Water (<1%), minor synthetic byproducts (<0.5%)
Ingredient Listing: 2-Piperazin-1-ylethanol — 100% by weight
Inhalation: Move person to fresh air, provide oxygen if breathing is difficult, seek medical advice
Skin Contact: Wash with soap and plenty of water for at least 15 minutes, remove contaminated clothing and shoes, medical attention required for persistent irritation
Eye Contact: Rinse immediately with copious amounts of water for at least 15 minutes, hold eyelids apart, seek immediate medical assistance
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting unless directed by medical personnel, seek immediate medical advice
Most Important Symptoms: Burning sensation, redness, pain, possible vision impairment
Notes to Physicians: Treat symptoms, provide supportive care, consider delayed effects from chemical exposure
Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Hazards from Combustion: Emits toxic fumes including nitrogen oxides and carbon monoxide
Protective Equipment: Self-contained breathing apparatus, full protective gear
Special Procedures: Prevent run-off from entering waterways, use water spray to cool fire-exposed containers, remain upwind, avoid breathing vapors
Personal Precautions: Wear chemical-resistant gloves, goggles, protective clothing
Environmental Precautions: Prevent further leakage or spillage, do not allow product to enter drains, surface water, or soil
Methods for Cleanup: Absorb with inert material (sand, earth, vermiculite), place in suitable closed container for disposal, ventilate area well
Additional Advice: Remove all ignition sources, avoid breathing dust, vapor, or mist, evacuate nonessential personnel from affected area
Safe Handling: Handle in a chemical fume hood, avoid contact with skin, eyes, and clothing, practice good industrial hygiene
Storage Conditions: Store in tightly sealed containers in a cool, dry, well-ventilated area, away from oxidizers, acids, or incompatible substances
Other Precautions: Keep away from sources of ignition, take precautionary measures against static discharge, keep out of direct sunlight and moisture
Occupational Exposure Limits: No specific regulatory values, avoid unnecessary exposure
Engineering Controls: Use adequate exhaust ventilation, ensure eyewash stations and safety showers nearby
Personal Protective Equipment: Chemical splash goggles, impervious gloves (nitrile or neoprene), flame-retardant lab coat, closed shoes
Respiratory Protection: Use approved respirator if airborne exposure risk exists
Hygiene Measures: Wash hands after handling, avoid eating, drinking, or smoking during use, launder contaminated clothing before reuse
Appearance: Colorless to pale yellow liquid
Odor: Mild, amine-like
Molecular Weight: 130.19 g/mol
Boiling Point: ~287°C
Melting Point: -3°C
Flash Point: 151°C
Solubility: Soluble in water, alcohol, and organic solvents
Vapor Pressure: <0.01 mmHg at 20°C
Density: 1.03 g/cm3 at 20°C
pH: 11.5 (100 g/L in water at 20°C)
Chemical Stability: Stable under normal temperature and pressure
Incompatible Materials: Strong oxidizers, acids, acyl chlorides
Hazardous Decomposition: Releases carbon monoxide, carbon dioxide, nitrogen oxides on burning
Polymerization: Will not occur under recommended usage and storage conditions
Conditions to Avoid: Excessive heat, exposure to moisture, contact with incompatible substances
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Oral LD50 (rat) >2000 mg/kg; Dermal LD50 (rabbit) >2000 mg/kg
Skin Effects: Irritation, possible burns
Eye Effects: Serious eye damage, pain, redness
Inhalation Effects: May cause respiratory tract irritation, cough
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity from available studies
Sensitization: Not expected to cause skin or respiratory sensitization
Ecotoxicity: Low toxicity to aquatic organisms, limited data on chronic exposure
Mobility: Fully miscible in water, potential for groundwater contamination
Persistence and Degradability: Biodegradable under aerobic conditions, breakdown expected over weeks
Bioaccumulation: Low potential for bioaccumulation in aquatic or terrestrial species
Other Information: Avoid uncontrolled release to the environment, recommended to keep out of water courses, drains, and soil
Waste Handling: Place in clearly labeled and tightly closed container, avoid release into environment
Disposal Methods: Incinerate under controlled conditions in approved facility, follow local, regional, and national regulations
Contaminated Packaging: Rinse thoroughly before disposal, dispose as hazardous waste
Additional Advice: Contact certified chemical waste disposal contractor for guidance on proper destruction and decontamination
UN Number: Not regulated as hazardous for transport under ADR, IATA, or IMDG
Proper Shipping Name: 2-Piperazin-1-ylethanol
Transport Hazard Class: Not classified as dangerous
Packing Group: None assigned
Special Precautions: Avoid leaks or spills in transit, keep containers upright and secure, protect from physical damage
TSCA: Registered and listed under US Toxic Substances Control Act
REACH Status: Pre-registered in Europe; further inquiries through supplier
SARA Title III (Sections 302/304, 311/312): Not listed as an extremely hazardous substance, not subject to reporting thresholds
WHMIS (Canada): D2B – Toxic material causing other toxic effects
Other Local, State, Federal Regulations: Users should consult with local environmental, health, and safety authorities, product not currently subject to specific federal workplace exposure limits in most jurisdictions
