Material Safety Data Sheet: 2-Phenylpyrrolidine

Identification

Product Name: 2-Phenylpyrrolidine
Synonyms: N/A
Chemical Formula: C10H13N
CAS Number: 4545-34-0
Recommended Use: Laboratory research, chemical synthesis
Manufacturer: Chemical supply firms, university laboratories
Contact Information: Check the supply label for the latest phone numbers and addresses
Emergency Phone: National poison control or the local emergency service always works best for fast help

Hazard Identification

Classification: Skin irritant, eye irritant, hazardous to aquatic life
Label Elements: Pictograms might include exclamation mark, fish and tree
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, harmful if inhaled, potentially toxic to aquatic ecosystems, long term exposure brings chronic health concern
Precautionary Statements: Wear gloves, goggles, work in a well-ventilated place
Other Hazards: Avoid breathing vapor, mist or dust

Composition / Information on Ingredients

Chemical Name: 2-Phenylpyrrolidine
CAS Number: 4545-34-0
Concentration: 100% pure substance
Impurities: Trace levels from synthesis, usually negligible for hazard considerations

First Aid Measures

Eye Contact: Rinse right away with gently flowing water, lift eyelids to wash under the lids, remove contact lenses if easy to do so, keep washing at least 15 minutes
Skin Contact: Wash with soap and plenty of water, remove contaminated clothing and shoes, seek medical advice if redness or irritation happens
Inhalation: Move outside, open air helps dilute exposure, seek fresh air and watch for trouble breathing, call medical help if symptoms persist
Ingestion: Rinse mouth, do not induce vomiting unless told by a professional, get medical attention right away
Notes for Physician: Treat symptomatically, monitor airways, support respiration as needed

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, alcohol-resistant foam
Unsuitable Extinguishing Media: Straight-stream water sprays can spread burning chemical
Specific Hazards: Burning releases toxic fumes (nitrogen oxides, carbon monoxide)
Special Protective Equipment: Firefighters wear self-contained breathing apparatus plus full protective gear
Advice: Keep containers cool by spraying with water, avoid breathing smoke

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, lab coat, avoid inhaling vapors and dust
Environmental Precautions: Block spills from flowing outside or into drains
Cleanup Methods: Use inert absorbent (like sand or vermiculite), scoop into secure container, ventilate the place, wash area after picking up residue
Disposal: Collect waste in labeled, sealed containers for hazardous disposal

Handling and Storage

Safe Handling: Open container in fume hood, keep lids tightly closed, use neat dispensing tools
Avoid: Direct skin, eye, and lung contact; rough handling might tip containers
Storage Conditions: Seal jars tightly, store in cool, dry locker marked for hazardous chemicals, shade from direct sunlight, lock away from food and incompatible materials
Incompatibles: Oxidants, acids, acid chlorides

Exposure Controls and Personal Protection

Engineering Controls: Fume hood use, air extraction keeps vapors low
Personal Protective Equipment: Gloves (nitrile), snug goggles or face shield, long sleeves or lab coat, closed shoes
Respiratory Protection: Mask with suitable filter for chemicals, always use in well-ventilated spot
Hygiene Measures: Wash hands after handling, keep workspace tidy, never eat or smoke in lab
Monitoring: Use leak alarm or air monitors for regular large-scale work

Physical and Chemical Properties

Appearance: Colorless to light yellow oily liquid
Odor: Slight amine scent
Molecular Weight: 147.22 g/mol
Boiling Point: Around 260°C
Melting Point: Below room temperature
Solubility: Partly mixes into water, dissolves well in organics (alcohol, ether, chloroform)
Vapor Pressure: Low at normal temperatures
Flash Point: About 130°C
Partition Coefficient: Log Kow around 2-3 (expected for aromatic amine)
pH: Not available as pure substance
Other Information: Not explosive, not an oxidizer

Stability and Reactivity

Chemical Stability: Lasts for years if kept sealed, stable in typical lab storage
Reactivity: Will not react under normal lab use
Conditions to Avoid: Excess heat, open flames, prolonged air or moisture
Incompatible Materials: Strong acids, oxidizing agents, acid chlorides
Hazardous Products: Burning or breakdown gives toxic gases, especially nitrogen oxides and carbon oxides
Polymerization: No risk of sudden polymerization under normal use

Toxicological Information

Routes of Exposure: Lungs, skin, eyes, mouth
Acute Effects: Causes irritation, redness, and swelling at contact points
Chronic Effects: Regular skin contact risks dermatitis, inhalation exposure over time might damage upper airways
LD50 (rat, oral): Data not specific, typical for aromatic pyrrolidines, oral toxicity expected in gram amounts
Sensitization: Can leave allergies after repeated contact
Carcinogenicity: Not on IARC or NTP lists, similar compounds sometimes linked with increased risk. No direct evidence, but take extra care
Mutagenicity: Not specifically tested, but closely related chemicals raise suspicion
Other Health Effects: Large doses might impact liver or kidney

Ecological Information

Aquatic Toxicity: Harms aquatic wildlife even at low concentrations
Persistence and Degradability: Slow to break down in river water or soil
Bioaccumulative Potential: Tends to build up in living creatures
Mobility in Soil: Moves through loose sand or soil, might reach roots or groundwater
Other Information: Avoid any release to streams, treat rinses and spills as hazardous

Disposal Considerations

Disposal Method: Send liquid or contaminated solids as hazardous waste, keep labeled, follow local hazardous chemical disposal steps
Container Rinsing: Use smallest water amount, treat rinsate as chemical waste, don’t rinse down regular drain
Incineration: Only in certified chemical incinerators
Local Regulations: Contact waste authorities to check requirements
Precaution: Never reuse empty containers for food or drink, triple rinse and deface label before disposal

Transport Information

UN Number: Not officially assigned as of latest data
Proper Shipping Name: 2-Phenylpyrrolidine
Class: Not routinely regulated as dangerous for global shipping, but some countries request handling as hazardous constituent
Packing Group: Usually III (least dangerous in class), but check local shipment laws
Environmental hazards: Mark package if shipping near water or through fragile habitats
Transport Precautions: Label all packages, seal tightly, protect from rough handling, ship with full hazard documents

Regulatory Information

OSHA: Not set for Permissible Exposure Limit, treat as hazardous
TSCA: Listed in US Toxic Substances Act registry
EINECS/ELINCS: Registered in European chemical registry
REACH: Not registered for mass manufacture in European Union as of now
SARA Title III: Not specifically listed, but report large spills or emergency releases
California Prop 65: Not on restricted list, but similar aromatics have restrictions
Workplace: Post right-to-know signs, train chemical handlers, update chemical inventory yearly