Product Name: 2-Morpholinoethanol
Synonyms: N-(2-Hydroxyethyl)morpholine; HE-Morpholine
Chemical Formula: C6H13NO2
Molecular Weight: 131.17 g/mol
CAS Number: 622-40-2
Recommended Use: Used as a chemical intermediate, solvent, and auxiliary in industrial and research applications.
Supplier Details: Manufacturer or distributor information should be consulted directly from the source or product packaging for emergency contact and address.
Hazard Classification: Acute toxicity (Oral, Dermal, Inhalation), Skin irritation, Eye damage, Specific Target Organ Toxicity (Single Exposure).
Label Elements: Pictograms: GHS07 (Exclamation Mark), GHS05 (Corrosive).
Signal Word: Warning
Hazard Statements: Harmful if swallowed, Causes skin irritation, Causes serious eye damage, May cause respiratory irritation.
Precautionary Statements: Avoid breathing vapors, wash skin thoroughly after handling, use only outdoors or in well-ventilated area, wear protective gloves and eye/face protection, in case of inadequate ventilation, wear respiratory protection.
Symptoms of Exposure: Burning sensation, coughing, nausea, vomiting, skin reddening, and severe eye damage.
Chemical Name: 2-Morpholinoethanol
CAS Number: 622-40-2
Concentration: >99% (by weight)
Impurities: None identified at reportable concentrations (trace process impurities depend on supplier’s manufacturing standards).
Inhalation: Move person to fresh air, monitor breathing, seek immediate medical attention if symptoms persist.
Skin Contact: Remove contaminated clothing, rinse skin with plenty of running water for minimum 15 minutes, seek medical advice for prolonged irritation.
Eye Contact: Rinse cautiously with water for several minutes, remove contacts if present and easy to do, continue rinsing, get urgent ophthalmologic care due to risk of irreversible damage.
Ingestion: Rinse mouth, do not induce vomiting, never give fluids to unconscious person, call for medical help immediately.
Notes for Doctors: Treat symptomatically with focus on potential corrosive and systemic effects, monitor respiratory and cardiovascular function.
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide.
Special Hazards: May emit toxic fumes of carbon monoxide, nitrogen oxides, and other organic vapors upon combustion.
Protective Equipment: Full protective clothing including self-contained breathing apparatus for firefighters.
Advice for Firefighters: Stay upwind of fire, cool containers with water if exposed to flames, avoid inhaling smoke or fumes.
Additional Precautions: Avoid runoff into drains and watercourses.
Personal Precautions: Evacuate area, ventilate, use protective equipment as necessary to avoid skin and eye contact.
Environmental Precautions: Prevent further leakage if it is safe to do, restrict release into sewers, soil, and waterways.
Methods for Clean-Up: Absorb spill with inert material (like sand or vermiculite), place in chemical waste container, ensure area is ventilated, dispose according to local regulations.
Decontamination: Wash residual area with water and suitable cleaning agents, avoid sources of ignition.
Handling: Use only with adequate ventilation, wear appropriate skin and eye protection, avoid ingestion and inhalation, prevent contact with skin and eyes, wash hands thoroughly after handling.
Storage Conditions: Store in tightly closed container, out of direct sunlight, at a cool, dry, and well-ventilated spot, remove sources of ignition, keep away from incompatible substances such as strong acids, strong bases, oxidizers.
Special Precautions: Use spill trays for liquid storage, avoid damage to containers, maintain chemical inventory management.
Engineering Controls: Operate in a fume hood or with local exhaust, keep airborne concentration below recommended limits.
Exposure Limits: Occupational exposure limits have not been set for 2-Morpholinoethanol, general chemical hygiene is required.
Respiratory Protection: Wear approved respirator if exposure is possible above airborne exposure limits.
Skin Protection: Chemical-resistant gloves (nitrile or neoprene), lab coat or apron.
Eye Protection: Safety goggles with side shields, face shield recommended for high-risk operations.
Other Protection: Emergency eye wash and safety shower in work area, avoid unnecessary exposure.
Appearance: Clear, colorless to pale yellow liquid.
Odor: Slight amine-like.
Melting Point: -3 °C
Boiling Point: 242 °C
Flash Point: 120 °C (closed cup)
Auto-ignition Temperature: 275 °C
Upper/Lower Explosion Limits: Lower explosive limit: 1.3%, Upper explosive limit: 7.9% (by volume in air).
Vapor Pressure: 0.01 mmHg (20 °C).
Solubility: Miscible with water and most solvents.
Viscosity: Approx. 23 mPa·s (20 °C)
pH: Weakly basic (in water solution)
Chemical Stability: Stable under normal temperature and recommended storage conditions.
Possible Reactions: Reacts with strong oxidizing agents, acids, acid chlorides, acid anhydrides.
Conditions to Avoid: Heat, open flames, sources of ignition.
Hazardous Decomposition: Carbon monoxide, carbon dioxide, nitrogen oxides, other organic compounds.
Polymerization: Does not occur under recommended conditions.
Acute Toxicity: Oral LD50 (rat): 1630 mg/kg, Dermal LD50 (rabbit): >2000 mg/kg, Inhalation LC50 (rat): data not established.
Skin Irritation: Causes irritation, redness, possible blistering on prolonged contact.
Eye Damage: Causes severe irritation, potential for eye damage.
Respiratory Sensitization: May cause coughing and respiratory tract irritation.
Chronic Effects: Extended exposure can cause dermatitis and possible liver or kidney effects.
Carcinogenicity, Mutagenicity, Reproductive Hazard: Not classified by IARC, ACGIH, NTP, or OSHA as carcinogen; no studies indicating mutagenic or reproductive toxicity in animals.
Ecotoxicity: Moderately toxic to aquatic organisms, LC50 (fish, 96hr): 215 mg/L (Species: Leuciscus idus).
Persistence and Degradability: Readily biodegradable by aquatic and soil microorganisms.
Bioaccumulation Potential: Log Kow: -1.15 (low potential for bioaccumulation).
Mobility in Soil: High water solubility suggests large mobility in the environment.
Other Adverse Effects: Avoid material discharge to stormwater and natural waters.
Waste Handling: Dispose of unused product and contaminated packaging through a licensed hazardous waste disposal contractor.
Disposal Methods: Follow local, regional, and national guidelines for disposal of hazardous chemical waste, do not discharge to drains.
Container Handling: Rinse empty containers with copious amounts of water, remove or obliterate labels before disposal, triple rinse when possible.
UN Number: Not regulated by DOT, ADR, IMDG, or IATA for transport in most concentrations.
Proper Shipping Name: 2-Morpholinoethanol
Transport Hazard Class: Not classified as dangerous for transport.
Packing Group: Not assigned.
Environmental Hazards: Not a marine pollutant.
Special Transport Precautions: Use suitable containers, avoid spillage during loading and unloading, comply with standard transport practices for industrial chemicals.
TSCA Status: Listed on the US Toxic Substances Control Act Inventory.
EINECS/ELINCS Status: Listed (EINECS Number: 210-730-4).
REACH Status: Registered under EU REACH regulations.
SARA 313: Not subject to reporting requirements.
California Proposition 65: Not listed as a carcinogen or reproductive toxin.
Other Regulations: Comply with workplace safety, environmental protection, and transportation guidelines in all applicable local, state, national, and international laws.
