Chemical Name: 2-Morpholinoethanesulphonic Acid
Synonyms: MES, 2-Morpholinoethane sulfonic acid
CAS Number: 4432-31-9
Molecular Formula: C6H13NO4S
Molecular Weight: 195.24 g/mol
Product Use: Buffering agent in biochemistry, laboratory research
Supplier Details: Name, address, contact phone number from supplier’s documentation
Emergency Phone: Provided by manufacturer or regional poison center
GHS Classification: Not classified as hazardous according to GHS criteria
Hazard Statements: Not regarded as a health or physical hazard under normal handling
Pictogram: None assigned
Signal Word: None required
Precautionary Statements: Avoid inhalation of dust, contact with eyes and skin. Typical good laboratory hygiene prevents most issues.
Health Hazards: May cause mild irritation to eyes, skin, or respiratory tract if exposed to high concentrations
Environmental Hazards: Not expected to pose significant risks without large accidental releases
Chemical Identity: 2-Morpholinoethanesulphonic Acid
Concentration: Typically >99% when supplied as analytical grade
Impurities: Trace manufacturing byproducts possible, less than 1%
Other Ingredients: None declared when supplied in pure form
Inhalation: Remove to fresh air. Seek medical attention if breathing becomes difficult.
Skin Contact: Wash with plenty of water and soap. Remove contaminated clothing.
Eye Contact: Rinse cautiously with water for at least 15 minutes. Remove contact lenses if present.
Ingestion: Rinse mouth with water. Get medical advice if feeling unwell.
Symptoms: Expect mild irritation to eyes and mucous membranes as main risk.
Medical Attention: Provide symptomatic treatment based on individual response.
Suitable Extinguishing Media: Use carbon dioxide, dry chemical powder, foam, or water spray depending on size of fire
Specific Hazards: Under fire, may produce irritating sulfur oxides and nitrogen oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Special Precautions: Avoid runoff from fire control entering drains or water bodies
Combustion Products: Sulfur oxides, nitrogen oxides, carbon oxides
Personal Precautions: Avoid producing dust. Use gloves, goggles, and dust mask. Ensure adequate ventilation.
Environmental Precautions: Avoid releasing large amounts into sewers, soil, or waterways.
Containment: Sweep up and collect as much as possible using clean tools. Place material in suitable container for disposal.
Cleanup Methods: Wash contaminated area with plenty of water after removal.
Handling: Avoid inhaling dust or allowing contact with skin and eyes. Use in a well-ventilated area. Employ practices minimizing dust generation.
Hygiene Measures: Wash hands after use. Prohibit eating, drinking, or smoking around open product.
Storage Conditions: Keep container tightly CLOSED. Store in a cool, dry, well-ventilated place, away from incompatible substances such as strong oxidizers.
Packaging Materials: Prefer plastic or glass containers. Label containers properly.
Occupational Exposure Limits: No specific limits assigned. Consider working below typical nuisance dust limits (10 mg/m³ total dust, 3 mg/m³ respirable fraction).
Engineering Controls: Use local exhaust or mechanical ventilation to reduce airborne exposure. Employ enclosures and process controls where necessary.
Respiratory Protection: Dust mask or respirator for dusty conditions.
Hand Protection: Chemical-resistant gloves such as nitrile or latex.
Eye Protection: Safety glasses or goggles.
Skin Protection: Standard laboratory clothing.
Environmental Exposure Controls: Minimize environmental release. Treat effluent in accordance with local regulations.
Appearance: White crystalline powder
Odor: Odorless
Melting Point: 300°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Highly soluble in water
pH (1% solution): About 5.5–6.7
Vapor Pressure: Negligible at ambient temperature
Specific Gravity: 1.438 (water = 1)
Partition Coefficient (log Kow): Data not available
Flash Point: Not flammable
Explosive Properties: Not explosive
Autoignition Temperature: Not self-igniting
Chemical Stability: Stable under standard laboratory conditions
Reactivity: No hazardous reactions expected with typical substances
Incompatible Materials: Strong oxidizing agents may react with MES
Conditions to Avoid: Extreme heat, incompatible chemicals
Hazardous Decomposition Products: May release sulfur oxides, nitrogen oxides, carbon monoxide, carbon dioxide if heated to decomposition
Polymerization: Not known to occur
Acute Toxicity: Oral LD50 (rat) > 5000 mg/kg
Skin Irritation: Minimally irritating based on similar compounds
Eye Irritation: May cause mild mechanical irritation
Inhalation: Dust may cause mild irritation to mucous membranes
Chronic Effects: No known evidence of long-term adverse effects at low levels
Carcinogenicity: Not listed by IARC, NTP, OSHA as carcinogenic
Sensitization: No evidence from available data.
Other Health Effects: Handle with care as with all laboratory chemicals
Ecotoxicity: Low risk in small quantities; high concentrations may affect aquatic systems
Persistence/Degradability: Readily biodegradable under environmental conditions
Bioaccumulation: Not likely due to high water solubility
Mobility in Soil: High, potential for leaching to groundwater if released in significant quantities
Other Adverse Effects: Minimal environmental hazard if treated through standard wastewater systems
Product: Dispose of in accordance with local, regional, and national regulations. Small amounts can go with laboratory waste if allowed.
Contaminated Packaging: Triple-rinse containers before disposal or recycling. Follow label requirements.
Special Precautions: Do not release untreated product into sewers or natural water bodies.
UN Number: Not regulated as hazardous for ground, air, or water shipment
UN Proper Shipping Name: Not classified for transport
Transport Hazard Class: None assigned
Packing Group: None assigned
Environmental Hazards: Not classified as a marine pollutant
Special Precautions for Transport: Protect containers from damage and moisture. Avoid contaminating public waterways during transport.
OSHA Status: Not listed as hazardous under OSHA Hazard Communication Standard
SARA Title III (Sections 302/311/312/313): Not subject to reporting
TSCA Inventory: Listed
REACH Status: Registered or exempted for laboratory use
WHMIS Classification: Not subject to Canadian WHMIS requirements
Other Regulations: Follow all international, national, and local legislation relating to chemical safety
