Product Name: 2-Methyl-5-Nitroimidazole
CAS Number: 431-03-8
Synonyms: 2-Methyl-5-nitro-1H-imidazole; MNZ
Recommended Use: Chemical synthesis, laboratory reagent
Manufacturer: Contact information as per local supplier’s label
Emergency Telephone: As displayed on supplier label, local poison control
Address: Refer to manufacturer or supplier documentation
Hazard Classification: Acute toxicity (oral, dermal), Eye irritation, Skin irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, skin contact causes irritation, may cause eye irritation, possible mutagenic effects
Precautionary Statements: Avoid breathing dust, avoid skin and eye contact, wear gloves and goggles, wash thoroughly after handling
Chemical Name: 2-Methyl-5-Nitroimidazole
Concentration: ≥98%
Molecular Formula: C4H5N3O2
Impurities: Trace contaminants related to synthesis route, typically below detectable limits
Other Ingredients: None expected in analytical-grade material
Inhalation: Remove to fresh air, keep at rest, monitor breathing, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin with plenty of water and mild soap, consult a doctor for persistent redness or discomfort
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses, keep eyes open during rinsing, seek advice if irritation continues
Ingestion: Rinse mouth, drink water if conscious, do not induce vomiting, get immediate medical help
Most Important Symptoms: Headache, nausea, irritation, redness, coughing if inhaled, eye watering if splashed
Note to Physician: Treat symptomatically and provide supportive care
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide
Unsuitable Extinguishing Media: Strong water jets may spread material
Hazardous Combustion Products: Nitrogen oxides, carbon monoxide, carbon dioxide, irritating fumes
Special Protective Equipment: Firefighters use self-contained breathing apparatus and chemical protective clothing
Specific Hazards: Combustible dust, dust can form explosive mixtures with air
Personal Precautions: Wear gloves, eye protection, and dust mask; avoid contact and breathing dust
Environmental Precautions: Prevent entry into drains, soil, surface water; notify authorities in case of large release
Method of Cleanup: Scoop spilled material into containers using non-sparking tools, ventilate area, wash residue with water and detergent
Handling: Use in a ventilated area, use local exhaust, handle with chemical-resistant gloves and safety glasses, avoid dust buildup, ground containers when dispensing
Storage: Store in tightly sealed container, cool, dry, well-ventilated place, avoid exposure to sunlight and moisture, keep away from food and drink, label clearly
Engineering Controls: Use fume hood or sufficient ventilation to control airborne levels
Personal Protective Equipment: Safety goggles, chemical-resistant gloves, lab coat, dust mask or respirator as needed
Exposure Limits: No OSHA PEL or ACGIH TLV established; minimize exposure as a precaution
Hygiene: Wash hands after handling, do not eat or drink near product, launder contaminated clothing before reuse
Appearance: Yellow to tan crystalline powder
Odor: Odorless or faint chemical smell
Odor Threshold: Not available
pH: Not available
Melting Point: 165-169°C
Boiling Point: Not applicable, decomposes
Flash Point: None established, not flammable in solution
Solubility: Soluble in water, ethanol, DMSO; low solubility in organic solvents like ether
Partition Coefficient (log Kow): Not determined
Vapor Pressure: Negligible at room temperature
Density: 1.37 g/cm³ (estimated)
Decomposition Temperature: Above 170°C
Evaporation Rate: Not applicable
Chemical Stability: Stable under recommended handling and storage conditions
Conditions to Avoid: High temperature, sunlight, moisture, open flames
Incompatible Materials: Strong oxidizers, reducing agents, strong acids or bases
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides, irritating or toxic gases on combustion or decomposition
Polymerization: Will not occur
Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: Moderate toxicity if swallowed; data indicate LD50 (oral, rat) between 300–2000 mg/kg
Symptoms: Headache, dizziness, nausea, irritation to eyes, skin, mucous membranes
Chronic Effects: Repeated exposure can cause liver changes, methemoglobinemia, possible mutagenicity
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Sensitization: Not classified as skin sensitizer, but prolonged contact may aggravate sensitive skin
Other Data: No evidence for reproductive toxicity at low doses, handle with caution
Persistence and Degradability: Moderately persistent in environment, partial biodegradation expected
Bioaccumulation Potential: Low tendency to bioaccumulate in aquatic organisms
Ecotoxicity: Toxic to aquatic life at high concentrations; data on fish: LC50 (96h, fish) > 100 mg/L
Mobility in Soil: Mobile in water, risk of contamination in groundwater if spilled
Additional Remarks: Do not allow uncontrolled release into environment, collect and dispose responsibly
Product Disposal: Dispose through licensed chemical waste contractor, do not drain or landfill untreated
Container Disposal: Triple rinse and dispose as hazardous waste or follow local regulations
Special Precautions: Label all waste, minimize dust generation, use compatible containers for collection
UN Number: Not classified as hazardous for transport based on available data
Proper Shipping Name: Chemical not regulated for transport (ADR, IMDG, IATA)
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Keep containers tightly closed, transport according to regulations, shield from moisture
EU Regulation: Not listed for special restriction, handle as potentially harmful substance
OSHA Status: Not specifically regulated in the US
WHMIS Classification (Canada): Not classified, general laboratory chemical
SARA Title III: Not reportable under Section 313
Inventory Status: Listed on major chemical inventories (TSCA, EINECS)
Other Regulation: Follow national and local chemical safety, waste, and transport laws, obtain guidance for large quantities or industrial use
