Product Name: 2-Methyl-4-Nitroimidazole
Chemical Formula: C4H5N3O2
CAS Number: 1656-61-5
Synonyms: 4-Nitro-2-methylimidazole
Recommended Use: Laboratory chemical, research and development applications
Supplier Details: Manufacturer and distributor contact information on request
Emergency Contact: Chemtrec: 1-800-424-9300 (USA)
Classification: Acute toxicity (oral, dermal, inhalation); Eye irritation; Skin irritation
GHS Label Elements: Signal word: Danger; Pictograms: Skull and crossbones, exclamation mark
Hazard Statements: Harmful if swallowed, in contact with skin or inhaled; Causes skin and serious eye irritation; May cause respiratory irritation
Precautionary Statements: Avoid breathing dust; Wash thoroughly after handling; Wear protective gloves, clothing, and eye/face protection; Use only in well-ventilated area
Other Hazards: May form hazardous decomposition products; Dust may cause explosion in confined space
Chemical Name: 2-Methyl-4-Nitroimidazole
Percentage: Pure compound (≥ 98%)
CAS Number: 1656-61-5
Molecular Weight: 127.10 g/mol
Impurities: No significant impurities affecting classification reported
General Advice: Remove from exposure and seek medical attention. Show this sheet to attending physician
Inhalation: Move person to fresh air immediately. Keep comfortable for breathing. Seek medical attention if symptoms occur
Skin Contact: Remove contaminated clothing. Wash skin with soap and water for at least 15 minutes. Get medical attention for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical help if irritation persists
Ingestion: Rinse mouth. Do not induce vomiting. Seek medical attention or contact poison center if the individual feels unwell
Suitable Fire Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical or carbon dioxide
Specific Hazards: Emits toxic fumes containing nitrogen oxides, carbon oxides when heated to decomposition
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Explosion Hazard: Dust accumulation may form explosive mixtures with air
Advice for Firefighters: Evacuate area, control runoff, prevent leakage into sewage, use water spray to cool unopened containers
Personal Precautions: Evacuate non-essential personnel, ventilate area, avoid breathing dust, wear personal protective equipment
Environmental Precautions: Prevent substance from entering drains, surface water, and soil
Spill Clean-up Methods: Sweep or scoop up and place in appropriate closed container for waste disposal. Clean spill area thoroughly, ventilate area. Dispose of according to local regulations
Additional Advice: Avoid raising dust during clean-up. Use non-sparking tools. Decontaminate surfaces with soap and water
Safe Handling: Use in ventilated area. Avoid breathing dust, vapors, or spray. Avoid contact with eyes, skin, and clothing. Wear appropriate PPE
Hygiene Practices: No eating, drinking, or smoking in work area. Wash thoroughly after handling
Conditions for Safe Storage: Keep container tightly closed and dry in a cool, well-ventilated area. Store away from incompatible materials such as strong oxidizers and acids
Incompatibilities: Avoid excessive heat, direct sunlight, sources of ignition, oxidizing agents, strong acids
Occupational Exposure Limits: None established for this specific substance; follow general dust exposure guidelines (OSHA PEL: 15 mg/m³ total dust, 5 mg/m³ respirable fraction)
Engineering Controls: Local exhaust ventilation, process enclosure, or other engineering controls to keep airborne levels below recommended limits
Personal Protective Equipment: Chemical-resistant gloves (nitrile), safety goggles, lab coat or apron, and dust mask or respirator (NIOSH-approved) where risk of exposure exists
Environmental Controls: Minimize release to the environment through source control and spill management
Appearance: Yellow crystalline powder
Odor: No significant odor
pH: Not available
Melting Point: 186–190 °C
Boiling Point: Data not available
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not classified as flammable, but dust may be explosible
Vapor Pressure: Not available
Vapor Density: Not available
Relative Density: Not available
Solubility: Soluble in water
Partition Coefficient (log Pow): Data not available
Decomposition Temperature: Not specified
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions
Reactivity: No hazardous reactivity under normal conditions
Hazardous Reactions: May react with strong oxidizing agents or acids
Conditions to Avoid: Strong heat, open flames, incompatible materials
Incompatible Materials: Oxidizers, strong acids
Hazardous Decomposition Products: Emits toxic gases such as nitrogen oxides, carbon monoxide, carbon dioxide
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin; LD50 (oral, rat): >100 mg/kg (estimated, not empirically reported)
Irritation: Causes skin and serious eye irritation
Sensitization: Not reported
Chronic Effects: Information on long-term effects limited; potential for mutagenicity or reproductive toxicity not adequately studied
Carcinogenicity: Not classified by IARC, NTP, or OSHA
Other Data: Symptoms may include coughing, irritation, redness, nausea
Ecotoxicity: Data on acute and chronic aquatic toxicity not available; presumed harmful to aquatic life based on structure
Persistence and Degradability: Potential for persistence due to nitro group, environmental degradation likely slow
Bioaccumulation Potential: No data; likely low due to hydrophilicity
Mobility in Soil: Some mobility expected, avoid contamination of ground and surface waters
Other Adverse Effects: Avoid uncontrolled release, may impact aquatic organisms with prolonged exposure
Waste Treatment Methods: Collect and transfer to a properly labeled and approved chemical waste disposal facility
Chemical Waste Disposal: Follow federal, state, and local environmental control regulations. Do not discharge to drains, surface water, or soil
Contaminated Packaging: Containers should be emptied and triple-rinsed; dispose in accordance with official requirements
Special Precautions: Avoid formation of dust; ensure waste containers tightly closed and clearly labeled
UN Number: Not regulated as dangerous goods under current transport regulations (US DOT, IATA, IMDG)
Proper Shipping Name: Not regulated
Transport Hazard Class: None
Packing Group: None
Marine Pollutant: No
Special Precautions: Prevent container damage and spillage during transport, keep away from incompatible substances
Inventory Status: Listed or exempt on TSCA, EINECS/ELINCS, DSL, and other major chemical inventories
US Regulations: Not listed as a specifically regulated substance under SARA Title III, CERCLA, or RCRA
EU Regulations: Not classified as a dangerous substance under current directives, but standard controls for laboratory chemicals apply
Workplace Labeling: GHS-compliant labeling required, hazard pictograms and warning statements advised
Additional Notes: Safety data reviewed periodically for compliance and accuracy in alignment with local, state, and international legislation
