Material Safety Data Sheet – 2-Methyl-3-Methylthio Pyrazine

1. Identification

Product Name: 2-Methyl-3-Methylthio Pyrazine
Chemical Formula: C6H8N2S
CAS Number: 28583-20-4
Synonyms: 2-Methyl-3-(methylthio)pyrazine
Manufacturer: (Insert company name and address)
Recommended Use: Food flavoring, fragrance compound
Restrictions: Avoid use in pharmaceuticals or medical applications unless specifically evaluated for such purposes

2. Hazard Identification

GHS Classification: Not classified as hazardous according to GHS standards
Route of Exposure: Eyes, skin, inhalation, ingestion
Signal Word: None
Hazard Statements: May cause mild irritation to skin, eyes, or respiratory tract, especially in sensitive individuals
Precautionary Statements: Prevent contact with skin and eyes, avoid inhaling dust or vapor, use in well-ventilated environments
Pictograms: None required under typical use

3. Composition / Information on Ingredients

Chemical Identity: 2-Methyl-3-Methylthio Pyrazine
Concentration: 100%
Impurities: None expected at significant levels
Molecular Weight: 140.20 g/mol
Other Names: Flavor ingredient, pyrazine derivative

4. First Aid Measures

Inhalation: Move exposed person to fresh air and keep comfortable, seek medical attention if respiratory symptoms develop
Skin Contact: Remove contaminated clothing, wash skin thoroughly with plenty of soap and water, consult a doctor if irritation persists
Eye Contact: Rinse immediately with water for at least 15 minutes, hold eyelids apart, seek medical help for persistent discomfort
Ingestion: Rinse mouth with water, give small amount of water to drink, do not induce vomiting, consult a physician if symptoms occur

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Media: High volume water jet may spread material
Hazardous Combustion Products: Emits toxic fumes of nitrogen oxides, carbon oxides, and sulfur oxides in the event of fire
Protective Equipment: Firefighters should wear self-contained breathing apparatus and standard protective gear
Specific Hazards: Product may create hazardous decomposition byproducts if involved in fire

6. Accidental Release Measures

Personal Precautions: Avoid direct contact, ventilate affected area, use protective gloves and eyewear
Environmental Precautions: Prevent large spills from entering drains, water courses, or soil
Methods for Cleanup: Absorb material with inert substrate such as sand or earth, scoop up used absorbent and transfer to suitable waste container, wash area with water and detergent

7. Handling and Storage

Handling: Work with good ventilation, avoid inhaling dust or vapor, do not expose to open flame or high heat, wear personal protective equipment as appropriate
Storage Conditions: Store in tightly closed containers in cool, dry, and well-ventilated areas, protect from light, moisture, and incompatible materials like strong oxidizers
Other Notes: Keep out of reach of children, label containers clearly, maintain inventory of stored quantities for quick response

8. Exposure Controls / Personal Protection

Occupational Exposure Limits: No specific exposure limits established
Engineering Controls: Use mechanical ventilation, local exhaust, or process enclosure to minimize airborne concentrations
Personal Protective Equipment: Nitrile gloves, chemical safety goggles, protective clothing as needed, NIOSH-approved respirator in case of insufficient ventilation or high vapor concentrations
Hygiene Measures: Wash hands thoroughly after handling, keep food and drink away from work areas, remove contaminated clothing and wash before reuse

9. Physical and Chemical Properties

Appearance: Pale yellow liquid or solid (crystalline)
Odor: Potent roasted, nutty, and sulfurous aroma
Odor Threshold: 0.01-0.1 parts per billion
pH: Not applicable
Melting Point: 41-43 °C
Boiling Point: Approx. 209 °C
Flash Point: >100 °C (closed cup)
Evaporation Rate: Not available
Flammability: Not highly flammable, avoid ignition sources
Vapor Pressure: Negligible at room temperature
Vapor Density: Heavier than air
Solubility: Slightly soluble in water, soluble in alcohol, ether, and organic solvents
Partition Coefficient: log Kow approx. 1.6
Viscosity: Not determined
Decomposition Temperature: Not available

10. Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling practices
Reactive Hazards: Reacts with strong oxidizers and acids
Conditions to Avoid: Heat, open flame, incompatible chemicals
Hazardous Decomposition: Nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide
Polymerization: Polymerization not expected under normal use

11. Toxicological Information

Routes of Exposure: Skin, eyes, ingestion, inhalation
Acute Effects: Mild skin and eye irritation in sensitive users
Chronic Effects: No reliable data for long-term health impacts, avoid prolonged or repeated exposure
Sensitization: No data, treat as sensitizer in occupational settings
Carcinogenicity: Not listed as carcinogen by IARC, OSHA, NTP
LD50 (oral, rat): Not determined, estimated to be greater than 500 mg/kg based on similar compounds
Potential Symptoms: Irritation of respiratory tract, headache, nausea if frequent exposure occurs

12. Ecological Information

Toxicity to Aquatic Life: Not well studied, low solubility in water suggests limited immediate risk, but avoid bulk release
Persistence/Degradability: Readily degradable under aerobic conditions over time
Bioaccumulation: Log Kow below 2, not expected to bioaccumulate significantly
Mobility in Soil: Moderately mobile due to low water solubility
Other Information: Prevent entry into waterways or sewers, as effects on aquatic organisms remain largely uncharacterized

13. Disposal Considerations

Waste Treatment Methods: Dispose of small quantities as chemical waste in accordance with local and national regulations, avoid disposal to municipal sewers
Container Disposal: Triple rinse, dispose of via licensed hazardous waste contractor
Special Precautions: Label all containers clearly, avoid disposing with regular household garbage, consult regulatory agencies for bulk disposal

14. Transport Information

UN Number: Not regulated for transport
Proper Shipping Name: 2-Methyl-3-Methylthio Pyrazine
Transport Class: Non-hazardous under ADR, IMDG, IATA regulations
Packing Group: Not applicable
Labels: No special labels needed under standard transport
Other Requirements: Prevent leaks from containers, store upright, separate from food products during shipment

15. Regulatory Information

Inventory Listings: Listed or exempted from major chemical inventories (TSCA, EINECS, DSL)
Safety Regulations: Subject to general safety measures under workplace safety rules, not targeted by specific hazard legislation
Labeling Requirements: Follow common workplace labeling with name, hazard statement if needed, manufacturer contact
Other Notes: Product use in food governed by national food safety laws, consult authorities if using in products for export