Product Name: 2-Methyl-3-Methoxy Pyrazine
CAS Number: 28525-93-5
Synonyms: 2-Methyl-3-Methoxypyrazine, Methyl Methoxypyrazine
Formula: C6H8N2O
Molecular Weight: 124.14 g/mol
Supplier/Manufacturer: [Enter actual contact details depending on supply chain]
Recommended Use: Lab chemical, flavor ingredient
Emergency Contact: [Facility-specific phone number]
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Acute toxicity oral (Category 4)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, harmful if swallowed, may cause respiratory discomfort
Pictograms: Exclamation mark
Precautionary Statements: Wear gloves/protective clothing/eye protection, avoid inhalation and ingestion, wash after handling, seek medical advice if feeling unwell
Potential Health Effects: Irritates eyes, skin, and respiratory tract; inhalation can cause throat and lung discomfort
Environmental Impact: May be harmful to aquatic life with long lasting effects; minimize release to environment
Chemical Name: 2-Methyl-3-Methoxy Pyrazine
CAS Number: 28525-93-5
Concentration: >99%
Impurities: Less than 0.5% related pyrazine derivatives
Additives: None known
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, seek medical advice if irritation persists
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing and wash before reuse, seek medical attention for persistent irritation
Inhalation: Move person to fresh air, keep comfortable for breathing, seek immediate medical advice if symptoms develop
Ingestion: Rinse mouth with water, do not induce vomiting, consult a physician or contact poison control
Most Important Symptoms: Irritated eyes or skin, difficulty breathing, gastrointestinal upset upon ingestion
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, or alcohol-resistant foam
Unsuitable Media: Direct water jet on burning substance may spread flames
Hazardous Combustion Products: Oxides of carbon and nitrogen, possible toxic fumes
Firefighting Equipment: Self-contained breathing apparatus, full protective gear
Special Advice: Control run-off water to prevent environmental contamination, approach fire from upwind
Personal Precautions: Use proper personal protective equipment, avoid inhaling vapors or dust, ventilate area well
Environmental Precautions: Prevent product entering drains or watercourses, contain spill using inert materials like sand
Cleanup Methods: Scoop up with non-sparking tools, sweep and place in a chemical waste container for disposal, wash spill area with water and detergent, avoid generating dust or aerosols
Handling: Wear protective gloves and safety goggles, use in a well-ventilated area or fume hood, avoid inhaling fumes, don’t eat or drink during use, practice good hygiene
Storage Conditions: Store in tightly closed containers, keep in a cool, dry, well-ventilated space, protect from light and heat sources, keep away from strong oxidizers, label storage area clearly, restrict access to trained personnel only
Engineering Controls: Local exhaust ventilation, fume hood usage, eye wash stations and safety showers nearby
Personal Protective Equipment: Protective gloves (nitrile recommended), safety goggles, lab coat, respiratory protection if ventilation inadequate
Exposure Limits: No specific occupational exposure limits established; minimize exposure as a precaution
Hygiene Measures: Remove contaminated clothing, wash hands and face after handling, avoid work practices that create dust or aerosols
Appearance: Clear to pale yellow liquid or crystalline solid
Odor: Strong, earthy, bean-like, pyrazine aroma
Odor Threshold: Extremely low — detectable in parts per trillion for sensitive individuals
pH: Not available
Melting Point: 14-16 °C
Boiling Point: 140-145 °C at 14 mm Hg
Flash Point: >70 °C (closed cup)
Evaporation Rate: Not determined
Solubility: Soluble in ethanol, slightly soluble in water
Vapor Pressure: Low
Density: ~1.12 g/cm³
Stability: Stable under normal conditions, avoid excessive heat long-term
Partition Coefficient: Not available
Chemical Stability: Stable at room temperature under recommended storage conditions
Possibility of Hazardous Reactions: No dangerous reactions under normal use
Conditions to Avoid: Excessive heat, flame, light, open containers
Incompatible Materials: Strong oxidizing agents, acids
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, possible toxic organic fumes at high temperatures
Acute Toxicity: May cause moderate symptoms if ingested (nausea, gastric discomfort); oral LD50 (rat) estimated >200 mg/kg
Skin Corrosion/Irritation: Mild irritant, repeated exposure causes redness and dryness
Serious Eye Damage/Irritation: May cause conjunctivitis, burning, watering
Respiratory Effects: Inhalation may cause cough, sore throat, headache
Skin Sensitization: Not a known sensitizer
Chronic Effects: No long-term data available; minimize repeated exposure
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not classified as carcinogenic, mutagenic, or toxic for reproduction by OSHA, NTP, IARC
Other Relevant Effects: Strong odor can trigger headaches or nausea in sensitive individuals
Aquatic Toxicity: Moderately toxic to aquatic organisms, may disrupt the behavior of sensitive species at low concentrations
Persistence and Degradability: Expected to degrade slowly in the environment, limited data on biodegradation
Bioaccumulative Potential: Low due to rapid biological breakdown
Mobility in Soil: Likely to leach slowly, low volatility in open settings
Other Adverse Effects: Don’t discharge large quantities to drains, water bodies, or soil; follow best practice for chemical disposal to avoid unnecessary contamination
Waste Disposal Methods: Gather waste into properly labeled, sealable chemical containers, consult local chemical disposal company or hazardous waste facility; incinerate at an approved site if available
Contaminated Packaging: Rinse and dispose containers according to local or national regulations, avoid re-using chemical bottles
Environmental Precautions: Do not flush into surface water, sewer, or soil
UN Number: Not assigned
UN Proper Shipping Name: Not regulated for transport under most codes
Transport Hazard Class: Not classified as hazardous for road, rail, air, or sea transport
Packing Group: Not applicable
Special Precautions for Transport: Use spill-proof containers, segregate from food and feedstuff cargos, transport upright and secure to prevent accidental damage or leakage
Environmental Hazards: Not considered marine pollutant, but prudent to contain and label shipments
Safety, Health and Environmental Regulations: Check national and local inventories, some regions list as flavoring agent subject to use limitations
OSHA Hazards: Irritant
TSCA Status: Listed on US Toxic Substances Control Act Inventory
Other Regulatory Listings: Reach registration not required under <1 tonne/year in the EU; not listed as a controlled substance
Labeling Requirements: Signal word “Warning,” hazard statements and pictograms per international GHS guidelines
Restrictions: Avoid non-industrial exposure, keep out of reach from unauthorized users
Reference Documents: SDS available through product supplier, consult workplace chemical safety coordinator for location-specific rules
